Figure 4
From: Factors affecting immunogenicity of BCG in infants, a study in Malawi, The Gambia and the UK
Concentrations of plasma zinc (Zn 2+ ), CRP and IFN-γ in Malawian infants. Zinc deficiency was not detected in the majority of the Malawian infants although 6 of 63 infants showed zinc deficiency (< 65 μg/dL). Levels of CRP greater than 10 mg/L were detected in 8 Malawian infants. The median IFN-γ responses to M. tb PPD were different between early vaccinated infants with rainy (n = 40) and dry season (n = 23) of birth (P < 0.001, Mann Whitney test) while the plasma zinc and CRP concentrations were unaffected by season of birth (P > 0.05, Mann Whitney test). The median levels of zinc, CRP and IFN-γ are indicated in red.