Skip to main content

Table 7 Positive predictive values of Crossing point (Cp) values with different cut-off limits for detection of severe sepsis/septic shock, for blood samples with a positive SeptiFast test for Gram-negative bacteria

From: Quantitative data from the SeptiFast real-time PCR is associated with disease severity in patients with sepsis

Cut-off Cp value

Escherichia coli(n = 33)

Klebsiella pneumoniae/oxytoca(n = 13)

Gram-negative bacteria, other* (n = 11)

Gram-negative bacteria total (n = 57)

<15.0

100% (3/3)

100% (1/1)

0% (0/1)

80% (4/5)

<17.5

100% (5/5)

100% (2/2)

0% (0/1)

88% (7/8)

<20.0

37% (5/11)

100% (2/2)

0% (0/2)

47% (7/15)

<22.5

30% (7/23)

29% (2/7)

20% (1/5)

29% (10/35)

<25.0

30% (8/27)

22% (2/9)

33% (3/9)

29% (13/45)

>25

24% (8/33)

15% (2/13)

27% (3/11)

23% (13/57)

  1. For samples that were positive for Gram-negative bacteria with Cp >25 (n = 12) the result is presented as >25 by the software, and not with continuous variables.
  2. Data is presented as percentages (No. of SeptiFast positive samples from patients with severe sepsis /No. of SeptiFast positive samples in total, according to cut-off).
  3. *Including: Enterobacter cloacae (n = 5), Pseudomonas aeruginosa (n = 5), and Serratia marcescens (n = 1).