Table 5 Number of positive samples and median Crossing point (Cp) values of all bacteria detected by Septifast PCR, grouped into severe sepsis/septic shock and non-severe sepsis cases
Species identified by Septifast | Severe sepsis/septic shock | Non severe sepsis | P-value for comparison between groups | ||
|---|---|---|---|---|---|
No. of cases | Cp median (range) | No. of cases | Cp median (range) | ||
Gram positive bacteria | 17 | 16.7 (7.3-21.7) | 25 | 19.9 (8.8-22.2) | 0.007 |
Staphylococcus aureus | 8 | 16.8 (10.4-21.7) | 16 | 20.3 (13.0-22.2) | 0.045 |
Streptococcus speciesa | 5 | 16.6 (14.7-16.8) | 8 | 18.5 (17.0-19.9) | 0.002 |
Enterococcus faecalis | 2 | 18.1 (17.1-19.2) | 1 | 8.8 | NRb |
Streptococcus pneumoniae | 2 | 13.5 (7.3-19.8) | 0 | NR | |
Gram negative bacteria | 13 | 17.1 (11.2-24.3) | 44 | 21.9 (8.5-25.0) | 0.004 |
Escherichia coli | 8 | 16.4 (13.7-22.6) | 25 | 21.0 (17.8-25.0) | 0.006 |
Klebsiella pneumoniae/oxytoca | 2 | 14.1 (11.2-17.0) | 11 | 22.8 (20.9-25.0) | NR |
Enterobacter cloacae/aerogenes | 2 | 23.6 (23.0-24.3) | 3 | 20.5 (8.5-25.0) | NR |
Pseudomonas aeruginosa | 1 | 21.6 | 4 | 23.2 (19.2-25.0) | NR |
Serratia marcescens | 0 | 1 | 23.3 | NR | |
Total | 30 | 16.9 (7.3-24.3) | 69 | 20.9 (8.5-25.0) | <0.001 |