Figure 3From: Natural antibody response to Plasmodium falciparum merozoite antigens MSP5, MSP9 and EBA175 is associated to clinical protection in the Brazilian Amazon Percentage of recognition of different proteins by plasmas from asymptomatic (“A”) and symptomatic patients (“S”) from the same area. The tested antigens are shown on the x-axis while the percentages of plasmas with positive recognition (RI > 1) per clinical group are shown on the y-axis. The reactivity index RI was calculated by dividing OD values from sample plasmas against given antigens by the a media plus 2 standard deviations of OD values obtained with the same antigens recognized by 13 malaria-naïve subjects (see also Methods). Statistical differences are indicated as asterisks and were found for the MAD20-type sequence of MSP1 block 2: S > A (p = 0.0206), MSP5: A > S (p = 0.0069) and MSP9: A > S (p = 0.0047).Back to article page