From: Profile of infective endocarditis observed from 2003 - 2010 in a single center in Italy
No. (%) of patients | p | ||||
---|---|---|---|---|---|
Characteristic | TOTAL | Native valve | Prosthetic valve | ||
(189 events, 166 patients) | (118 events, 111 patients) | (71 events, 55 patients) | |||
Age (years), median [IQR] | 57 [43–72] | 53 [42–71] | 66 [50–75] | 0.01 | |
Male gender | 104 (63%) | 72 (65%) | 32 (58%) | 0.4 | |
Time from onset of symptoms to admission | |||||
< 7 days | 69 (37%) | 41 (35%) | 28 (39%) | ||
>7 and ≤21 days | 42 (22%) | 25 (21%) | 17 (24%) | ||
> 21 days | 55 (29%) | 34 (29%) | 21 (30%) | 1 | |
NA | 23 (12%) | 18 (15%) | 5 (7%) | ||
Co-morbidities | |||||
Cancer | 14 (7%) | 13 (11%) | 1 (1%) | 0.01 | |
Hypertension | 39 (21%) | 21 (18%) | 18 (25%) | 0.2 | |
Acute/chronic renal failure | 17 (9%) | 6 (5%) | 11 (15%) | 0.02 | |
Ischemic cardiopathy | 21 (11%) | 9 (8%) | 12 (17%) | 0.05 | |
Diabetes mellitus | 29 (15%) | 17 (14%) | 12 (17%) | 0.6 | |
COPD | 9 (5%) | 4 (3%) | 5 (7%) | 0.2 | |
CLD | 55 (29%) | 41 (35%) | 14 (20%) | 0.03 | |
HIV infection | 35 (19%) | 27 (23%) | 8 (11%) | 0.05 | |
CD4 cells/μL [IQR] | 268 [145–353] | 248 [124–313] | 447 [348–1814] | 0.008 | |
HIV-RNA cp/mL (n 22) | |||||
<10000 | 14 (40%) | 8 (30%) | 6 (75%) | ||
10000-100000 | 5 (14%) | 4 (15%) | 1 (13%) | 0.11 | |
>100000 | 4 (11%) | 4 (15%) | 0 | ||
NA | 12 (34%) | 11 (41%) | 1 (13%) | ||
HAART at IE | |||||
No | 21 (60%) | 15 (56%) | 6 (75%) | 0.2 | |
Yes | 14 (40%) | 12 (44%) | 2 (25%) | ||
Data are median [interquartile range] or numbers (%). |