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Table 2 Human papillomavirus genotype-specific prevalences among invasive cervical cancer cases, meta-analytical estimates of relative oncogenic potentials

From: Comparing human papillomavirus prevalences in women with normal cytology or invasive cervical cancer to rank genotypes according to their oncogenic potential: a meta-analysis of observational studies

HPV-

Prevalence*

 

Cases†, n

Pooled OR

95% CI

Studies‡, n

Cochran’s Q -test P

I2statistic, %

Between-study variance

 

n

(%)

6

17

(0.8)

2,208

0.08

0.04, 0.16

18

0.162

24.8

0.438

11

17

(1.1)

1,554

0.11

0.06, 0.19

15

0.407

4.1

0.049

16

1,680

(57.9)

2,902

 

Reference

27

   

18

372

(12.8)

2,902

0.63

0.51, 0.78

27

0.425

2.6

0.009

30

2

(0.5)

430

0.13

0.03, 0.60

3

0.881

0.0

0.000

31

122

(4.4)

2,745

0.22

0.14, 0.35

24

<0.001

55.9

0.696

33

128

(4.7)

2,728

0.22

0.12, 0.38

24

<0.001

65.1

1.152

34

1

(0.2)

666

0.21

0.06, 0.80

5

0.791

0.0

0.000

35

67

(2.7)

2,450

0.12

0.08, 0.17

21

0.408

4.0

0.032

39

24

(1.2)

2,017

0.17

0.09, 0.30

19

0.169

23.7

0.372

40

2

(0.2)

991

0.13

0.04, 0.45

8

0.197

28.9

0.889

42

3

(0.2)

1,573

0.05

0.02, 0.15

11

0.102

37.2

1.345

44

3

(0.4)

729

0.14

0.03, 0.66

5

0.147

41.1

1.324

45

119

(4.8)

2,464

0.35

0.22, 0.55

23

0.054

34.4

0.358

51

54

(2.7)

1,971

0.10

0.05, 0.20

19

0.014

46.3

0.901

52

96

(4.0)

2,394

0.16

0.11, 0.23

21

0.293

12.7

0.091

53

22

(1.1)

1,981

0.07

0.04, 0.12

16

0.380

6.4

0.075

54

1

(0.1)

1,263

0.06

0.02, 0.16

9

0.580

0.0

0.000

56

22

(1.0)

2,303

0.09

0.05, 0.16

20

0.278

14.2

0.230

58

127

(4.7)

2,685

0.24

0.15, 0.38

22

<0.001

56.8

0.583

59

24

(1.1)

2,218

0.17

0.09, 0.31

16

0.537

0.0

0.000

61

2

(0.2)

1,130

0.05

0.02, 0.14

8

0.739

0.0

0.000

62

1

(0.2)

558

0.07

0.02, 0.23

6

0.420

0.0

0.000

66

16

(0.7)

2,181

0.08

0.05, 0.14

18

0.799

0.0

0.000

67

4

(0.3)

1,342

0.21

0.06, 0.67

10

0.181

28.6

1.020

68

8

(0.5)

1,661

0.07

0.04, 0.14

14

0.439

0.8

0.013

69

9

(1.3)

672

0.28

0.09, 0.92

5

0.249

25.8

0.473

70

6

(0.4)

1,496

0.07

0.03, 0.14

11

0.565

0.0

0.000

71

1

(0.1)

672

0.03

0.01, 0.13

4

0.527

0.0

0.000

73

8

(0.7)

1,151

0.16

0.06, 0.41

10

0.617

0.0

0.000

74

1

(0.4)

264

0.10

0.00, 3.41

2

0.051

73.8

4.874

81

1

(0.1)

1,257

0.04

0.02, 0.10

11

0.966

0.0

0.000

82

4

(0.4)

892

0.13

0.04, 0.36

7

0.939

0.0

0.000

  1. *HPV prevalence among cases, with no distinction between simple and multiple infections, across the studies that reported counts of the HPV genotypes under consideration. †Number of cases tested for the given HPV genotype. ‡Number of studies included in each meta-analysis. Abbreviations: HPV human papilloma virus, OR odds ratio, CI confidence interval.
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BMC Infectious Diseases

ISSN: 1471-2334

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