Variable | Post-index (Cox) | |
---|---|---|
Hazard ratio (95% CI) | P-value* | |
Palivizumab non-compliance (ref. compliance) | 2.007 (1.392 - 2.894) | <0.001 |
Chronic lung disease | 2.035 (1.262 - 3.281) | 0.004 |
Congenital heart disease | 1.24 (0.778 - 1.978) | 0.366 |
33-36 wGA (ref. < 33 wGA) | 0.983 (0.634 - 1.522) | 0.937 |
Unknown wGA (ref. < 33 wGA) | 1.966 (1.206 - 3.206) | 0.007 |
Male gender (ref. female) | 1.152 (0.841 - 1.578) | 0.378 |
Geographic region – Northeast (ref. South) | 0.813 (0.469 - 1.407) | 0.459 |
Geographic region – Midwest (ref. South) | 1.226 (0.854 - 1.759) | 0.269 |
Geographic region – West (ref. South) | 0.862 (0.526 - 1.414) | 0.557 |
Index year – 2004 (ref. 2003) | 1.027 (0.618 - 1.706) | 0.919 |
Index year – 2005 (ref. 2003) | 0.893 (0.528 - 1.513) | 0.675 |
Index year – 2006 (ref. 2003) | 0.724 (0.415 - 1.262) | 0.254 |
Index year – 2007 (ref. 2003) | 0.827 (0.463 - 1.476) | 0.520 |
Index year – 2008 (ref. 2003) | 0.922 (0.534 - 1.591) | 0.769 |
Birth number – multiple birth (ref. single birth) | 0.418 (0.267 - 0.655) | <0.001 |
Birth number – unknown (ref. single birth) | 0.656 (0.313 - 1.373) | 0.263 |
Pre-index palivizumab use | 0.507 (0.276 - 0.933) | 0.029 |
NICU hospitalization at birth (ref. no NICU) | 1.354 (0.807 - 2.274) | 0.251 |
Unknown NICU hospitalization at birth (ref. no NICU) | 0.875 (0.312 - 2.457) | 0.800 |
Pre-index ambulatory visit | 0.677 (0.162 - 2.827) | 0.593 |
Pre-index emergency department visit | 1.746 (1.231 - 2.477) | 0.002 |
Pre-index inpatient hospitalization | 1.258 (0.387 - 4.085) | 0.703 |
Pre-index RSV-related hospitalization | 3.059 (1.574 - 5.942) | 0.001 |
Any pre-index comorbid condition | 2.003 (1.411 - 2.843) | <0.001 |
Low birth weight (<2500 g) | 0.906 (0.598 - 1.373) | 0.643 |
Birth month: May (ref. Sept) | 1.019 (0.587 - 1.769) | 0.947 |
Birth month: June (ref. Sept) | 0.7 (0.394 - 1.244) | 0.224 |
Birth month: July (ref. Sept) | 0.794 (0.456 - 1.384) | 0.416 |
Birth month: August (ref. Sept) | 0.713 (0.405 - 1.256) | 0.242 |