Figure 4

Histoplasma capsulatum . A: H. capsulatum can be observed in the plasma of histocytes and multinuclear giant cells and there were clear haloes around the bacteria. Hematoxylin & eosin x400. B: H. capsulatum can be clearly demonstrated in red by periodic acid-Schiff (PAS) stain (arrows): the shapes of the spores are round or oval, mostly of identical appearance. There are empty halos around the bacteria. PAS x400.