Molecular epidemiology and transmission dynamics of Mycobacterium tuberculosis in Northwest Ethiopia: new phylogenetic lineages found in Northwest Ethiopia

Table 2 Discriminatory capacities of spoligotyping and MIRU-VNTR 24-loci, alone or in combination for M. tuberculosis isolates from Ethiopia

Genotyping method	No. of different patterns	No. of isolates with unique pattern	No. of clusters	No. of isolates in clusters	Clustering rate (%)	RTI (%)	HGDI
Spoligotyping	69	43	26	201	82.4	64.8	0.88
MIRU-VNTR 24-loci	161	124	37	120	49.2	34.0	0.97
MIRU-VNTR 24-loci + Spoligotyping	170	134	36	110	45.1	30.3	0.97

HGDI= Hunter-Gastone discriminatory index, highest degree for HGDI is 1 that shows highest discriminatory power of a method, RTI= Recent transmission index.

ISSN: 1471-2334