Figure 4

Comparison of activation levels of antigen-specific populations between HIV ⁺ and HIV ^- donors. Antigen-specific responses (depicted in Figure 3) were assessed for expression of the activation markers CD38 and HLA-DR. (a) Activation levels for each combination of cytokines are depicted for the five persistent viral antigens and one non-persistent bacterial antigen. (b) Average activation levels for all cells responding to each antigen. The table below depicts the number of donors responding to each antigen by the three combinations of cytokines. Unpaired 2-tailed t-tests compared activation levels between HIV⁺ and HIV^- donors.