The risk of AIDS-defining events is decreasing over time in the German HIV-1 Seroconverter Cohort

BMC Infectious Diseases

Table 2 Adjusted Hazard Ratios of progression to first AIDS-defining event in the German HIV-1 Seroconverter Cohort, 2010

	HR†	95%CI		p-value
Calendar Period
Pre-1997	2.6	1.6	4.8	0.000
1997-2000	1.0	1.0	1.0	-
2001-2004	0.7	0.4	1.2	0.191
2005-2006	1.3	0.8	2.2	0.316
2007-2010	0.5	0.3	0.8	0.007
Sex, women	1.2	0.6	2.3	0.544
Age (per 10years increase in age)	1.3	1.1	1.5	0.001
HIV exposure category
men who have sex with men	1.0	1.0	1.0	-
Injecting drug users	1.4	0.8	2.7	0.229
heterosexuals	0.8	0.4	1.5	0.479
people from high endemic country	2.3	1.0	5.3	0.053
others*	1.1	0.2	8.0	0.910
unknown	1.6	0.6	4.4	0.340
Short HIV test interval ‡	1.3	1.0	1.8	0.056

* Occupational and blood transfusion.
†adjusted for calendar period, sex, age at seroconversion, HIV exposure category, short HIV test interval.
‡defined as 3months between last negative and first positive HIV test, or with laboratory evidence of seroconversion.
HR: Hazard Ratio; CI, confident interval.

ISSN: 1471-2334