Dynamics of ampicillin-resistant Enterococcus faecium clones colonizing hospitalized patients: data from a prospective observational study

Table 4 Invasive Infections with E. faecium

	ARE n = 16	ASE n = 6	p-value
Source of microbiological sample
- blood, n (%)	14 (88)	6 (100)	0.519
- abscess-drainage, n (%)	2 (12)	0
Polymicrobial infection, n (%)	5 (31)	4 (67)	0.155
Underlying disease, n (%)
Hematological malignancy	5 (31)	1 (17)
Hepatobiliary disease	2 (13)	5 (83)
Intestinal disease (M. Crohn)	1 (6)	0	0.031
Vascular graft	3 (19)	0
Other^a	5 (31)	0
Clinical presentation, n (%)
CVC-related infection	5 (31)	0
CVC colonization	4 (25)	1 (17)
Infection of vascular prosthesis	3 (19)	0	0.046
Cholangitis	2 (13)	5 (83)
Other^b	2 (13)	0
Days since admission, median (IQR)	20 (10-29)	3 (1-11)	0.089
Hospitalization on Intensive Care, n (%)	9 (56)	2 (33)	0.318
Death, n (%)	6 (38)	1 (17)	0.35

CVC central venous line; IQR interquartile range, ^a chronic obstructive pulmonary disease (2), intravenous drug use (1), lung cancer (1), spondylodiscitis (1); ^b intraabdominal abscess/peritonitis (1), unknown (1)

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