Table 1 Baseline Characteristics
Hematology UHBS | ICU UMCU | INV UHBS | ||
|---|---|---|---|---|
Group 1a | Group 1b | Group 2 | Group 3 | |
Patients | ||||
Screened patients; n | 34 | 33 | 184 | 25 |
Included patients (≥ 3RS); n(%) | 33 (97) | 21 (64) | 25 (14) | 22 (88)a |
Age, years; median (IQR) | 55 (48-63) | 53 (43-59) | 55 (44-66) | 69 (50-78) |
Male sex; n (%) | 18 (55) | 11 (52) | 19 (76) | 13 (59) |
Hospitalization during the previous year; n (%) | ||||
- At the same institution | 14 (42) | NA | 10 (40) | 11 (50) |
- At another hospital | 13 (39) | NA | NA | 4 (18) |
Death at end of follow-up, n (%) | 6 (18) | 12 (36) | 10 (40) | 7 (32) |
Episodes of hospitalization | 43 | NA | 29 | 22 |
Duration of hospitalization, days; median (IQR) | ||||
- Hematology/ICU | 27 (11-40) | NA | 28 (18-48) | NA |
- Any ward | 33 (19-53) | NA | 60 (42-78) | NA |
Referral from another ward in the hospital, n (%) | 2 (5) | NA | 16 (55) | NA |
Antibiotic treatment, n (%) | 34 (79) | NA | 28 (97) | NA |
- Duration, days; median (IQR) | 25 (15-38) | 20 (14-33) | ||
- Antibiotics at admission, n (%) | 14 (33) | 6 (21) | ||
- Days to start since admissionb, | 6 (4-11) | 2 (2-4) | ||
median (IQR) | ||||
Rectal swabs; n | 152 | 67 | 113 | 22 |
median per hospitalization (IQR) | 3 (2-4) | 3 (2-3)c | 3 (3-5) | 1 |
swabs containing E. faecium | 59 | 24 | 62 | 21 |
E. faecium isolates; n | 287 | 107 | 335 | 120 |
ARE; n (% of all isolates) | 157 (55) | 25 (23) | 288 (86) | 88 (73) |
- MT159 | 85 (30) | 25 (23) | 151 (45) | 73 (61) |
- MT1 | 17 (6) | 0 | 19 (6) | 10 (8) |
- MT 10 | 0 | 0 | 24 (7) | 0 |
- MT12 | 10 (3) | 0 | 47 (14) | 0 |
- MT 282 | 19 (7) | 0 | 0 | 5 (4) |
- other ARE | 26 (9)d | 0 | 47 (14)e | 0 |
MT159 in first swab, n (%) | 3 (7) | 3 (14)f | 5 (17) | NA |
MT159 acquisition during hospitalization, n (%) | 3 (7) | 1 (5) | 9 (31) | NA |