Table 2 Univariate conditional logistic analysis of risk factors for cryptococcal meningitis among patients with meningitis and encephalitis
Factors | Case [no.(%)] (n = 13) | Control [no.(%)] (n = 52) | P value | OR (95%CI) |
|---|---|---|---|---|
Gender | ||||
Female | 9 (21.4) | 51 (55.4) | Reference | |
Male | 14 (78.6) | 41 (44.6) | 0.190 | 1.81 (0.75-4.38) |
Age, years | ||||
0-5 | 4 (17.4) | 36 (39.1) | Reference | |
5-10 | 6 (26.1) | 29 (31.5) | 0.612 | 1.51 (0.31-7.35) |
10-15 | 9 (39.1) | 21 (22.8) | 0.033 | 4.36 (1.12-9.81) |
15-17 | 4 (17.4) | 6 (6.5) | 0.029 | 5.53 (1.19-25.79) |
Geographic location | ||||
Urban areas | 6 (26.1) | 32 (34.8) | Reference | |
Rural areas | 17 (73.9) | 60 (65.2) | 0.384 | 1.75 (0.54-5.66) |
Time from illness onset to hospitalization (days) | ||||
1-10 | 2 (8.7) | 35 (38.0) | Reference | |
10-20 | 3 (13.0) | 24 (26.1) | 0.398 | 2.22 (0.35-14.15) |
20-30 | 12 (52.2) | 17 (18.5) | 0.004 | 11.39 (2.20-59.02) |
≥30 | 6 (26.1) | 16 (17.4) | 0.055 | 5.05 (0.96-26.84) |
Contact with birds/droppings or saprophytes* | ||||
No | 5 (21.7) | 56 (60.9) | Reference | |
Yes | 18 (78.3) | 36 (39.1) | 0.001 | 9.32 (2.54-34.23) |
Underlying disease† | ||||
No | 17 (73.9) | 80 (87.0) | Reference | |
Yes | 6 (26.1) | 12 (13.0) | 0.160 | 2.05 (0.75-5.58) |