Table 1 Pregnant women with C. burnetii infection contracted during pregnancy.
Trimester of Exposure | Cases [n] | Clinical signs of Q fever (n) | antibiotic treatment (n) | Gestational week at delivery | Condition of the infant (n) | PCR on placenta positive | culture on placenta positive | PCR on colostrum/ milk positive | PCR on amniotic fluid positive | Ph1-IgG > 1:800 |
|---|---|---|---|---|---|---|---|---|---|---|
1 | 3* | fever (1), none (2) | Until delivery: | 40 | syndactyly2 (1), well3 (1) | 0/2 | 0/1 | 0/1 | 0/2 | 1 |
 · Clarithromycin (1) | ||||||||||
 · Trimethoprim-Sulfamethoxazol (1) | ||||||||||
 · (Sulfadiazin + Pyrimethamin for 2 weeks); Trimethoprim-Sulfamethoxazol + Pyrimethamin 1 (1) | ||||||||||
2 | 4 | none (4) |  · Trimethoprim-Sulfamethoxazol for one week (2) | 40 | RAD (1), well (3) | 0/4 | 0/3 | 1/3 | 0/3 | 1 |
 · Clarithromycin after delivery (1) | ||||||||||
|  |  |  |  · Trimethoprim-Sulfamethoxazol for four weeks (1) | |||||||
3 | 4 | pneumonia**(1), fever (1), none (2) |  · Erythromycin/Clarithromycin for three weeks (1) | 35-40 | RDS (1), well (3), Oligoamnios (1) | 0/2 | 0/2 | 0/1 | 0/14 | 0 |
 · without (2) | ||||||||||
 · Amoxicillin followed by Imipenem (1) |