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Table 2 Demographics of the unexposed individuals

From: High background rates of positive tuberculosis-specific interferon-γ release assays in a low prevalence region of UK: a surveillance study

  

Unexposed, age-matched individuals

  

TSpot positive n=13

TSpot negative n=136

Odds ratio

Univariate P

  

n

%

n

%

  

Age (years), median (range)

64

(45-87)

70

(25-93)

 

0.81

Male, n (%)

5

(38)

70

(52)

 

0.36

Ethnicity, n (%)

      

  White Caucasian

13

(100)

136

(100)

  

Country of birth

      

  UK born

9

(69)

126

(93)

0.18

0.006

  Other

4

(31)†

10

(7.4)

  

  Years since immigration, median (range)

43

(21-62)

52

(8-61)

  

Ever visited a high prevalence country, n (%)

4

(31)

47

(35)

 

0.84

  Years since last visit, median (range)

8.5

(0-40)

5.5

(0-60)

  

Ever resident in a high prevalence area >6/52, n (%)

2

(15)

27

(20)

 

0.64

Occupation: healthcare, prison, lab n (%)‡

4

(31)

18

(13)

 

0.09

BCG (history or scar), n (%)

      

  Yes

7

(54)

66

(49)

 

0.73

  No

4

(31)

44

(33)

  

  Unknown

2

(15)

26

(19)

  

Medical history, n (%)

      

  Comorbidity known to be associated with TB§

0

(0)

21

(16)

 

0.22

  Immunosuppresive medications

4

(31)

12

(9.2)

4.6

0.015

  Ever known to be exposed to TB

4

(31)

26

(19)

 

0.32

  Ever had treatment for tuberculosis

2

(15)

2

(1.5)

12

0.003

  1. † Germany (2), South Africa (1), Hong Kong (1).
  2. ‡ Percentages are those of those with valid data.
  3. § Diabetes mellitus (17), chronic renal failure (3), haematological malignancy (2), gastric surgery (1).
  4. Systemic steroids (12), methotrexate (4), hydroxychloroquine (2), anti-TNF alpha (2), sulfasalzine (1).