Figure 3From: Rapid and accurate detection of RMP- and INH- resistant Mycobacterium tuberculosisin spinal tuberculosis specimens by CapitalBio™ DNA microarray: A prospective validation study Hybridization pattern of spinal tuberculosis specimens with the DNA microarray. a. Hybridization pattern of the M. tuberculosis strain identification (white frame) b. RMP resistance with the rpoB 531 (TCG->TTG) mutation, the hybridization signal of probe TCG531TTG (solid rectangle) being higher than corresponding wild-type probe (dashed rectangle) c. RMP resistance test: rpoB 516 (GAC->GTC) mutation, the hybridization signal of probe GAC516GTC (solid rectangle) being higher than corresponding wild-type probe (dashed rectangle) d, e. INH resistance test: katG 315 (AGC->ACC) mutation, the hybridisation signal of probe katG AGC315ACC (solid rectangles) were higher than corresponding wild-type probe (dashed rectangles) e. INH resistance test: inhA-15 C-T mutation, the hybridisation signal of probe inhA 15C→T (solid rectangles) were higher than corresponding wild-type probe (dashed rectangles).Back to article page