In-vitroanalysis of the microbicidal activity of 6 contact lens care solutions

BMC Infectious Diseases

Table 1 Contact lens care solutions

trade name	manufacturer/ distributor	active ingredient	MMRDT	overnight	inactivation solution
AOSEPT PLUS	Ciba Vision	3.0% H₂O₂	6 h	8 h	Eye See neutralising solution*
BlueVision	Ciba Vision	3.0% H₂O₂	6 h	8 h	Eye See neutralising solution*
Easy Sept	Bausch & Lomb	3.0% H₂O₂	6 h	8 h	Eye See neutralising solution*
Oxysept Comfort	AMO	3.0% H₂O₂	6 h	8 h	Eye See neutralising solution*
Optifree Replenish	Alcon	0.001% polyquad (polyquaternium-1), 0.0005% aldox (myristamidopropyl dimethylamine)	6 h	8 h	IA II**
Solocare Aqua	Ciba Vision	0.0001% polyhexanide	4 h	8 h	IA II**

MMRDT - manufacturer’s minimum recommended disinfection time.
* Eye See neutralising solution, Lapis Lazuli Int. NV: catalase, 0.01% EDTA, 0.002% merthiolate, isotonic buffer solution.
** inactivation solution II: 3% TSB (Roth, Karlsruhe, Germany), 3% polysorbate 80 (Serva, Heidelberg, Germany), 3% saponin (Fluka, Buchs, Switzerland), 0.1% L-histidine (Serva, Heidelberg, Germany), 0.1% L-cysteine (Merck, Darmstadt, Germany) in 1 L deionised water.

ISSN: 1471-2334