Detection of P. aeruginosa harboring bla CTX-M-2, bla GES-1 and bla GES-5, bla IMP-1 and bla SPM-1causing infections in Brazilian tertiary-care hospital

Polotto, Milena; Casella, Tiago; de Lucca Oliveira, Maria Gabriela; Rúbio, Fernando G; Nogueira, Mauricio L; de Almeida, Margarete TG; Nogueira, Mara CL

doi:10.1186/1471-2334-12-176

Table 1 Antimicrobial susceptibility of carbapenem resistant P. aeruginosa *

From: Detection of P. aeruginosa harboring bla _CTX-M-2, bla _GES-1 and bla _GES-5, bla _IMP-1 and bla _SPM-1causing infections in Brazilian tertiary-care hospital

Isolate					Antimicrobials (zone diameter – mm)									DDST	blagenotype
No	Date	Unit	Infection site	CAZ	FEP	TZP	IPM	MEM	ATM	GEN	AK	CIP	LEV
				R ≤ 14	R ≤ 14	R ≤ 17	R ≤ 13	R ≤ 13	R ≤ 15	R ≤ 12	R ≤ 14	R ≤ 15	R ≤ 13
				S ≥ 18	S ≥ 18	S ≥ 18	S ≥ 16	S ≥ 16	S ≥ 22	S ≥ 15	S ≥ 17	S ≥ 21	S ≥ 17
Pa01	06/2009	CI	Urinary tract	6	6	6	10	8	10	6	6	6	6	N	bla _{CTX-M 2}
Pa02	06/2009	G-ICU	Lung	18	6	6	6	6	17	6	6	6	6	N	bla _IMP-1, bla _{CTX-M 2}
Pa03	06/2009	S-ICU	Urinary tract	20	6	18	6	13	12	6	15	6	6	P	bla _IMP-1
Pa04	06/2009	G-ICU	Lung	6	6	6	12	14	16	6	19	6	6	N	-
Pa05	07/2009	E-ICU	Blood	6	6	19	6	6	22	6	18	6	6	N	bla _SPM-1
Pa06	07/2009	E-ICU	Lung	6	6	10	11	14	14	12	16	6	6	N	-
Pa07	07/2009	N-Dep	Lung	6	6	6	6	6	16	6	6	6	6	N	-
Pa08	07/2009	C-Dep	Urinary tract	6	6	6	6	16	8	6	6	6	6	N	-
Pa10	07/2009	Outpatient	Urinary tract	6	6	13	6	6	23	6	15	6	6	N	bla _{CTX-M 2}
Pa11	07/2009	G-ICU	Lung	6	6	14	6	6	22	6	18	6	6	P	bla _SPM-1
Pa12	08/2009	E-ICU	Lung	6	6	16	6	6	19	6	21	6	6	P	bla _SPM-1
Pa14	08/2009	C-Dep	Urinary tract	6	6	6	10	15	10	6	18	6	6	N	-
Pa17	08/2009	P-ICU	Lung	17	6	16	13	17	16	6	6	6	6	N	bla _{CTX-M 2}
Pa18	08/2009	E-ICU	Lung	6	6	6	6	6	12	6	17	6	6	P	bla _SPM-1
Pa19	08/2009	P-ICU	Lung	6	6	6	6	6	14	19	23	23	10	N	-
Pa22	08/2009	SW	Skin	19	6	16	6	18	8	6	6	6	6	N	bla _{CTX-M 2}
Pa24	08/2009	C-Dep	Urinary tract	6	6	6	6	6	6	6	18	6	6	N	-
Pa27	08/2009	G-ICU	Catheter tip	6	6	10	10	15	8	6	19	6	6	N	-
Pa28	08/2009	G-ICU	Urinary tract	6	6	6	6	6	14	6	13	6	6	P	bla _SPM-1
Pa29	09/2009	C-Dep	Lung	23	6	17	6	22	12	6	6	6	6	N	-
Pa30	09/2009	P-ICU	Eyes	6	6	18	6	6	9	17	23	22	13	N	-
Pa31	09/2009	P-ICU	Abdominal	6	6	6	6	6	19	19	20	15	6	N	-
Pa32	09/2009	C-Dep	Lung	6	6	12	6	19	13	6	6	6	6	N	-
Pa33	09/2009	P-ICU	Lung	6	6	6	6	6	13	19	22	20	6	N	-
Pa34	09/2009	C-ICU	Bone	6	6	6	6	6	12	6	6	6	6	N	-
Pa35	09/2009	C-ICU	Lung	18	6	21	6	6	6	6	12	26	30	N	-
Pa36	09/2009	N-Dep	Lung	6	6	18	6	13	6	6	6	17	25	N	-
Pa37	09/2009	S-ICU	Urinary tract	6	6	14	6	6	20	6	20	6	6	P	bla _SPM-1
Pa39	09/2009	G-ICU	Catheter tip	25	6	14	6	24	21	6	6	6	6	N	-
Pa40	09/2009	P-ICU	Urinary tract	6	6	19	6	6	9	14	20	31	27	N	-
Pa41	09/2009	E-ICU	Lung	20	15	6	6	18	23	6	6	6	6	N	-
Pa42	09/2009	N-ICU	Eye	6	6	25	14	16	23	6	20	30	28	N	-
Pa43	10/2009	S-ICU	Lung	6	6	6	6	14	12	6	18	6	6	N	-
Pa44	10/2009	G-ICU	Lung	17	6	20	10	11	15	16	18	23	18	N	-
Pa45	10/2009	E-ICU	Skin	21	6	15	10	11	10	6	6	6	6	N	-
Pa47	11/2009	SW	Urinary tract	6	15	10	6	6	23	6	23	6	6	P	bla _SPM-1
Pa49	10/2009	N-ICU	Urinary tract	6	6	27	6	6	23	6	6	33	30	P	bla _IMP-1
Pa50	10/2009	SC	Bone	6	6	6	6	12	10	6	15	6	6	N	-
Pa51	10/2009	S-ICU	Urinary tract	6	6	6	6	19	18	6	6	6	6	N	-
Pa53	10/2009	C-UTI	Lung	20	6	18	6	6	14	6	6	6	6	N	bla _IMP-1, bla _{CTX-M 2}
Pa54	10/2009	E-ICU	Urinary tract	6	6	6	6	6	17	6	16	6	6	P	bla _SPM-1
Pa55	11/2009	ER	Urinary tract	6	6	6	6	6	17	6	6	6	6	N	bla _{CTX-M 2}
Pa57	11/2009	S-ICU	Urinary tract	26	6	6	6	6	25	6	6	6	6	N	bla _{CTX-M 2}
Pa58	11/2009	E-ICU	Urinary tract	6	6	6	6	6	21	6	18	6	6	P	bla _SPM-1
Pa59	11/2009	E-ICU	Lung	6	6	22	6	6	21	14	17	20	20	P	bla _IMP-1 , bla _GES-1
Pa60	11/2009	ER	Lung	6	6	10	12	6	8	6	6	6	6	N	bla _IMP-1, bla _{CTX-M 2}
Pa61	11/2009	N-Dep	Blood	6	6	6	6	6	10	6	6	6	6	N	bla _{CTX-M 2}
Pa62	11/2009	E-ICU	Lung	6	6	6	13	6	11	6	6	6	6	P	bla _IMP-1
Pa63	11/2009	E-ICU	Lung	6	6	15	6	6	6	6	19	6	6	N	-
Pa64	11/2009	N-Dep	Tendon	6	6	6	6	6	12	6	6	6	6	N	bla _GES-5
Pa65	11/2009	S-ICU	Lung	6	6	6	6	6	11	6	6	6	6	N	-
Pa66	11/2009	C-ICU	Lung	6	6	15	6	6	14	13	20	30	25	N	-
Pa67	11/2009	ER	Urinary tract	6	6	6	6	6	15	13	6	6	6	N	-
Pa69	11/2009	E-ICU	Lung	6	6	6	19	6	6	21	6	20	6	P	bla _SPM-1
Pa70	11/2009	E-ICU	Lung	6	6	6	6	11	11	12	6	6	6	N	-
Pa71	11/2009	E-ICU	Lung	6	6	6	6	6	6	6	6	6	6	N	bla _{CTX-M 2}

CAZ , ceftazidime; FEP , cefepime; TZP ,piperacillin-tazobactam; IMP , imipenem; MEM , meropenem; ATM , aztreonam, GEN , gentamicin, AK , amikacin; CIP ,ciprofloxacin; LEV , levofloxacin; ^† DDDS , double disc synergy test to detect MBL production , N , negative, P , positive, ER , emergence room; E-ICU , emergence intensive care unit; G-ICU , geral intensive care unit; S-ICU , semi-intensive care unit; C-ICU , cardiology intensive care unit; P-ICU , pediatrics intensive care unit, N-ICU , neonatal intensive care unit N-Dep , neurology department; C-Dep , cardiology department; SC , surgical ward, CI , cancer institute; R , resistant; S , susceptible.

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ISSN: 1471-2334

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