Infection rate of Eperythrozoon spp. in Chinese population: a systematic review and meta-analysis since the first Chinese case reported in 1991

Table 2 Overall Eperythrozoon infection rate by selected variables

Variable		Number of countributing studies	Total tested	Eperythrozoon positive	Crude infection rate (95% CI)	OR/Adjusted OR by area (95% CI)	Heterogeneity chi-square	Pvalue	Publication bias
Gender	Male	8	7129	2933	41.14	Ref.	—	—	None
	Male				(40.00 - 42.28)
	Female	8	7408	3127	42.21	1.03	26.02	<0.01
	Female				(41.09 - 43.33)	(0.86 - 1.24)
Age of enrolled population (yrs)	≤19	4	1771	1342	75.78	Ref.	—	—	†
	≤19				(73.78 -77.77)
	20-39	5	9288	1738	18.71	0.55	67.52^#	<0.01
	20-39				(17.92 -19.51)	(0.48 - 0.64)
	40-59	5	9330	1310	14.04	0.59	47.20 ^#	<0.01
	40-59				(13.34 -14.75)	(0.50 - 0.68)
	≥60	5	3459	411	11.88	0.80	5.80^#	0.02
	≥60				(10.80 -12.96)	(0.67 - 0.96)
	Age						94.47^#	<0.01
	Area						3980.23^#	<0.01
Occupation	Employees with the food industry exceptional	2	413	212	51.33	Ref.	—	—	†
	Employees with the food industry exceptional				(46.51 - 56.15)
	Employees in the food industry	3	1458	832	57.06	0.85	1.45^#	0.23
	Employees in the food industry				(54.52 - 59.60)	(0.66 - 1.10)
	Farmers	4	1551	754	48.61	1.98	4.78^#	0.03
					(46.12 - 51.10)	(1.07 - 3.64)
	Herdsmen	6	530	296	55.85	3.65	27.34^#	<0.01
					(51.62 - 60.08)	(2.25 - 5.93)
	Occupation						44.75^#	<0.01
	Area						641.56^#	<0.01
Contact history of animals	No	3	5548	575	10.36	Ref.	—	—	None
					(9.56 - 11.17)
	Yes	3	1413	808	57.18	6.40	233.38	<0.01
					(54.60 - 59.76)	(5.50 - 7.37)
Season	Winter & Spring	2	9127	460	5.04	Ref.			†
					(4.59 - 5.49)
	Summer & Autumn	2	10178	1564	15.37	4.26	6.91	<0.01
					(14.67 - 16.07)	(3.01 - 6.02)
Location	Urban area	2	839	633	75.45	Ref.	—	—	†
					(72.54 - 78.36)
	Rural area	2	1456	1190	81.73 (79.75 - 83.71)	2.83 (0.36 - 22.55)	21.86	<0.01

ISSN: 1471-2334