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Figure 4 | BMC Infectious Diseases

Figure 4

From: Effects of adenosine A2A receptor activation and alanyl-glutamine in Clostridium difficile toxin-induced ileitis in rabbits and cecitis in mice

Figure 4

Effects of ATL 370 and alanyl-glutamine on C. difficile toxin A-induced ileal histopathology. Toxin A (10 μg, B) caused mucosal disruption, increased cellularity and vascular congestion compared with PBS (A) in rabbit ileal tissues. Treatment with intravenous ATL 370 (1.5 ng, D) or intraluminal alanyl-glutamine (100 mM, C) reduced some epithelial injury. Marked preservation of mucosal architecture was noted in tissues treated with the combination of ATL and alanyl-glutamine (E)

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BMC Infectious Diseases

ISSN: 1471-2334

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