Table 1 Descriptive statistics related to 10 replicates of a reference sample at four target dilutions
From: HIV-1 low-level viraemia assessed with 3 commercial real-time PCR assays show high variability
Siemens | Abbott | Roche | ||
|---|---|---|---|---|
100 cop/ml | Mean (cop/mL) | 60.6 | 84.5 | 115.4 |
SD (cop/mL) | 26.7 | 27.7 | 38.3 | |
CV (%) | 44.0 | 32.8 | 33.2 | |
Undetected (%) | 0 | 0 | 0 | |
50 cop/ml | Mean (cop/mL) | 35.3 | 33 | 65.8 |
SD (cop/mL) | 15.3 | 22.5 | 22.7 | |
CV (%) | 43.2 | 68.1 | 34.5 | |
Undetected (%) | 0 | 0 | 0 | |
25 cop/ml | Mean (cop/mL) | 18.1 | 25.5 | 26.56 |
SD (cop/mL) | 8.7 | 10.4 | 22.1 | |
CV (%) | 48.1 | 40.7 | 83.1 | |
Undetected (%) | 0 | 0 | 10 | |
12 cop/ml | Mean (cop/mL) | 15.6 | 20.0 | 25.8 |
SD (cop/mL) | 6.6 | 6.6 | 19.9 | |
CV (%) | 42.2 | 32.8 | 77.1 | |
Undetected (%) | 20 | 70 | 20 |