Table 1 Summary of main clinical, laboratory and imaging findings from patient 1
Onset of symptoms (date) | Presenting symptoms | Site of R. equi infection (diagnostic technique) | CD 4 + cells, HIV-1 RNA (VL) | HAART | Treatment | Duration |
|---|---|---|---|---|---|---|
April 2002 | fever, cough | lung (culture of sputum, chest X-ray). disseminated infection (blood culture) | 123 cells/μl, VL < 50 copies/ml | didanosine, lamivudine, indinavir | induction (i.v.): vancomycin 500 mg q6h imipenem 500 mg q6h ceftriaxone 2 g qd ciprofloxacin 400 mg bid maintanance (p.o.): ciprofloxacin 500 mg bid | induction: 8 weeks maintanance:15 weeks |
May 2002 | seizures | head (brain MRI, culture of surgically removed brain abscess) | didanosine, lamivudine,indinavir | surgery, antibiotic therapy (see above) | ||
December 2002 | anisocoria, right hemiparesis, hypoaesthesia, hypoallaesthesia, dysmetria | CNS (brain MRI) | 143 cells/μl, VL < 50 copies/ml | didanosine, lamivudine, indinavir | i.v.: ciprofloxacin 400 mg tid vancomycin 500 mg q6h ceftriaxone 2 g qd | 3 weeks |