Figure 5
From: Delta neutrophil index as an early marker of disease severity in critically ill patients with sepsis
Time course of delta neutrophil index (DNI) values, white blood cell (WBC) counts, and absolute neutrophil counts (ANC) before and after the onset of severe sepsis/septic shock. On the basis of the optimal cut-off values (DNI, 6.5%; WBC, 16590/mm3; and ANC, 14100/mm3) presented in Table 3, DNI values already elevated before the onset of organ/circulatory failure in 36 (82%) of the 44 patients with severe sepsis/septic shock, and decreased over time after ICU admission (p < 0.001). In contrast, there were no changes in WBC counts (p =0.235) or ANC (p = 0.223) over time.