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Table 4 Haplotype frequencies and the risks of pulmonary tuberculosis

From: Fine mapping of genetic polymorphisms of pulmonary tuberculosis within chromosome 18q11.2 in the Chinese population: a case-control study

Haplotypes

Case

N (%)

Control

N (%)

cOR (95% CI)

P

aOR (95% CI)a

P a

rs8087945- rs12456774

      

   Ars8087945Ars12456774

746(64.5)

725(47.9)

1

 

1

 

   Ars8087945Grs12456774

159(13.8)

454(30.0)

0.34(0.28-0.42)

< 0.0001

0.34(0.27-0.42)

< 0.0001

   Grs8087945Ars12456774

75(6.5)

333(22.0)

0.22(0.17-0.29)

< 0.0001

0.22(0.16-0.29)

< 0.0001

   Grs8087945Grs12456774

176(15.2)

0(0)

-

0.994

-

0.994

rs4800417-rs8087945

      

   Crs4800417Ars8087945

813(70.3)

1176(77.8)

1

 

1

 

   Trs4800417Grs8087945

126(10.9)

278(18.4)

0.66(0.52-0.82)

0.0003

0.64(0.50-0.81)

0.0003

   Crs4800417Grs8087945

126(10.9)

55(3.6)

3.31(2.38-4.61)

< 0.0001

3.19(2.26-4.51)

< 0.0001

   Trs4800417Ars8087945

91(7.9)

2(0.2)

43.88(13.84-139.07)

< 0.0001

48.08(15.02-153.92)

< 0.0001

  1. a: Adjusted for age, sex, education, smoking and drinking.