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Table 3 CD4+ T-cell counts at relevant time points of the study

From: Long-term CD4+ T-cell count evolution after switching from regimens including HIV nucleoside reverse transcriptase inhibitors (NRTI) plus protease inhibitors to regimens containing NRTI plus non-NRTI or only NRTI

 

Pre-switch

Post-switch

Last observation

 

NNRTI

group

NRTI

group

NNRTI

group

NRTI

group

NNRTI

group

NRTI

group

Median (IQR): days from HAART

788

(489-1200)

1002

(646-1432)

896

(595-1331)

1103

(759-1620)

2080

(1398-2567)

2220

(1638-2663)

Median (IQR) CD4-count [cells/mm3]*

468

(321-660)

561

(402-758)

478

(322-683)

568

(386-799)

538

(389-742)

634

(446-871)

CD4+ increase (%) from baseline

138.8

125.3

143.9

128.1

174.5

154.6

N (%) CD4+ classes$

      

<200/mm3

61

(9.1%)

10

(4.5%)

44

(6.6%)

12

(5.3%)

30

(4.5%)

10

(4.4%)

201-350/mm3

140

(20.9%)

36

(16.0%)

147

(21.9%)

33

(14.7%)

92

(13.7%)

26

(11.6%)

351-500/mm3

167

(24.9%)

48

(21.3)

165

(24.6%)

45

(20.0%)

168

(25.0%)

33

(14.7%)

>500/mm3

303

(45.1%)

131

(58.2%)

315

(46.9%)

135

(60.0%)

381

(56.8%)

156

(69.3%)

  1. *Comparisons at Pre-switch: P < 0.0001; Post-switch: < 0.0001; Last observation: < 0.0001;
  2. $Comparisons at Pre-switch: P < 0.0038; Post-switch: < 0.0073; Last observation: < 0.0044;