Table 4 Cytokine concentrations in acute serum samples of patients with HFRS according to the causative agent and disease severity
Patient group | Mean levels (min-max) of cytokines (pg/ml) | |||
|---|---|---|---|---|
IL-10 | IL-12 | INF-γ | TNF-α | |
DOBV | 292.5 (2.24-6600) | 100.4 (1.94-544) | 89.1 (0-1916) | 9.8 (0-62.5) |
severe | 474.4 (12.4-6600) | 97.7 (10.9-544) | 131.5 (0-1916) | 12.3 (1.87-62.5) |
mild-moderate | 44.4 (2.24-328) | 104.0 (1.94-440) | 31.4 (0-354) | 6.3 (0-17) |
PUUV | 130.3 (6.63-2120) | 139.2 (0.98-637) | 24.1 (0.43-692) | 10.8 (0-138) |
severe | 89.9 (15.5-731) | 151.1 (2.49-570) | 46.6 (1.61-692) | 7.6 (2.47-15.2) |
mild-moderate | 148.6 (6.63-2120) | 133.8 (0.98-637) | 14.0 (0.43-203) | 12.3 (0-138) |