Figure 2

Time course of viral load and duration of viral shedding according to presence of pneumonia and antiviral treatment. Panels A and C: mean values and standard deviation (represented by bars) of influenza A/H1N1pdm in NPS at various time points after symptom onset; panels B and D: proportion of samples positive to influenza A/H1N1pdm PCR according to time from symptom onset. Panels A and B: patients with pneumonia vs. without pneumonia; Panels C and D: treated vs. untreated patients. In panel A the number of samples collected at days 0-1, 2-3, 4-5, 6-7, 8-9 and ≥10 were (for patients with pneumonia) 3, 8, 8, 9, 5, and 21 and (for patients without pneumonia) 8, 21, 30, 7, 14 and 10. In panel C the number of samples collected at days 0-1, 2-3, 4-5, 6-7, 8-9 and ≥10 were (for treated patients) 9, 24, 24, 23, 13 and 29, and (for untreated patients) 2, 5, 14, 13, 6 and 2.

* p ≤ 0.010, ** p ≤ 0.010, *** p ≤ 0.010; §: p = 0.002.