Mycobacterial infections in a large Virginia hospital, 2001-2009

BMC Infectious Diseases

Table 3 Host characteristics among patients meeting ATS/IDSA criteria for NTM lung disease

	Demographics			Lung disease			Host predisposition
Organism (N)	Age (median)	Sex M:F	Immigrant n (%)	COPD n (%)	Cystic Fibrosis n (%)	Other lung dz^a n (%)	DM/ESRD/CVD n (%)	Cancer n (%)	HIV n (%)	Transplant n (%)
Total meeting ATS/IDSA criteria (83)	59	28:55	1 (1)	19 (23)	6 (7)	13 (16)	11 (13)	10 (12)	3 (4)	5 (6)
MAC (57)	62	15:42	0	10 (18)	3 (5)	8 (14)	8 (14)	8 (14)	2 (4)	2 (4)
M. kansasii (4)	43	3:1	0	2 (50)	0	1 (25)	0	0	0	0
M. xenopi (4)	70	4:0^b	0	2 (50)	0	0	0	0	1 (25)	0
M. abscessus (3)	43	0:3	1 (33)	1 (33)	0	1 (33)	0	0	0	1 (33)
M. fortuitum (3)	62	0:3	0	0	0	1 (33)	1 (33)	2 (66)	0	0
Mixed^c (8)	42	4:4	0	2 (50)	3 (38^d)	1 (13)	2 (25)	0	0	2 (25)
Other^e (4)	59	2:2	0	2 (50)	0	1 (25)	3 (75)	0	0	0

^aOther lung disease = asthma, alpha-1-antitrypsin, interstitial lung disease, pulmonary alveolar proteinosis, pulmonary fibrosis, sarcoidosis, and silicosis.
^b M. xenopi associated with male gender, p = 0.01.
^cMixed included 4 MAC + M. abscessus infections, 1 MAC + M. fortuitum infection, 1 MAC + M. terrae infection, and 1 M. abscessus + M. chelonae infection. 5 of 8 M. abscessus infections were mixed, vs. 3 of 75 non-abscessus infections, p < 0.05.
^d Cystic fibrosis was statistically associated with mixed infections vs. non-mixed infections, p < 0.05.
^e Other infections included 1 each of M. chelonae, M. simiae, M. szulgai, and M. terrae.
DM = diabetes mellitus. ESRD = end-stage renal disease. CVD = collagen vascular disease.

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