Variables | INH resistant isolates | unadjusted OR | adjusted OR* | p | 95%CI | ||
---|---|---|---|---|---|---|---|
 |  | No. patients | n(%) clustered |  |  |  |  |
Social-demographic and clinical characteristics: | |||||||
Age (year) | 18~ | 34 | 12(35.3) | 1 | Â | Â | Â |
 | 30~ | 65 | 34(52.3) | 2.011 |  |  |  |
 | 60~ | 32 | 17(53.1) | 2.078 |  |  |  |
Sex | Female | 46 | 22(47.8) | 1 | Â | Â | Â |
 | Male | 85 | 41(48.2) | 1.163 |  |  |  |
County | Deqing | 55 | 27(49.1) | 1 | Â | Â | Â |
 | Guanyun | 76 | 36(47.4) | 0.933 |  |  |  |
BMI | ≥18.5 | 94 | 41(43.6) | 1 | 1 |  |  |
Index | <18.5 | 37 | 22(59.5) | 1.896 | 1.833 | 0.13 | 0.836-4.019 |
Treatment | New | 80 | 32(40.0) | 1 | 1 | Â | Â |
history | Previously | 51 | 31(60.8) | 2.325 | 2.159 | 0.040§ | 1.037-4.495 |
Sputum | negative | 49 | 18(36.7) | 1 | 1 | Â | Â |
smear | positive | 82 | 45(54.9) | 2.095 | 2.286 | 0.032§ | 1.075-4.863 |
Cavity | No | 111 | 50(45.0) | 1 | 1 | Â | Â |
 | Yes | 20 | 13(65.0) | 2.266 | 2.423 | 0.091 | 0.868-6.761 |
Bacteriological features: | |||||||
Drug | INH mono | 55 | 21(38.2) | 1 | 1 | Â | Â |
resistance | MDR-TB | 53 | 31(58.5) | 2.281 | 2.384 | 0.030§ | 1.089-5.220 |
 | PDR -TB | 23 | 11(47.8) | 1.484 | 1.627 | 0.348 | 0.588-4.496 |
katG | wt | 50 | 9(18.0) | 1 | 1 | Â | Â |
 | 315Thr | 74 | 54(73.0) | 12.3 | 12.7 | 0.001§ | 6.357-14.80 |
 | others | 7 | 0(0) | - | - |  |  |
inhA | wt | 103 | 59(57.3) | 1 | 1 | Â | Â |
 | -15T | 28 | 4(14.3) | 0.124 | 0.12 | 0.001§ | 0.038-0.375 |
Beijing | No | 26 | 4(15.4) | 1 | 1 | Â | Â |
genotype | Yes | 105 | 59(56.2) | 5.183 | 5.289 | 0.001§ | 1.832-15.26 |