Drug resistance | Total |
katG315Ser → * |
inhA-15C→ * |
katG+ | wt |
---|
Profile | Â | Arg | Asn | Thr | T |
inhA
§
| Â |
---|
   H | 55 | 2 | 1 | 28 | 12 | 0 | 12 |
MDR-TB
| Â | Â | Â | Â | Â | Â | Â |
   HR | 32 | 0 | 1 | 19 | 6 | 1 | 5 |
   HRS | 12 | 0 | 0 | 9 | 2 | 1 | 0 |
   HRE | 5 | 0 | 0 | 5 | 0 | 0 | 0 |
   HRSE | 4 | 0 | 1 | 2 | 1 | 0 | 0 |
PDR-TB
| Â | Â | Â | Â | Â | Â | Â |
   HS | 13 | 0 | 0 | 5 | 3 | 0 | 5 |
   HE | 2 | 0 | 0 | 0 | 1 | 0 | 1 |
   HSE | 8 | 0 | 1 | 5 | 1 | 0 | 1 |
- NOTE: H, isoniazid; R, rifampicin; S, streptomycin; E, ethambutol.
- MDR-TB, multidrug-resistant tuberculosis; PDR-TB, polydrug-resistant tuberculosis.
- *: No. of isolates with mutations in single gene.
- §: No. of isolates with mutations in multiple genes. Two INH resistant isolates shared the mutation in katG and inhA gene simultaneously: one with katG315Thr and inhA-15T mutations and the other with katG315Arg and inhA-15T mutation.