Hypoglycaemia in severe malaria, clinical associations and relationship to quinine dosage

BMC Infectious Diseases

Table 3 Predictors of Hypoglycaemia post admission

	Univariable analysis		Multiple regression analysis
	Unadjusted OR [CI]	P-Value	Adjusted OR [CI]*	P-Value
Treatment:Regimen	0.97 [0.67 - 1.41]	0.88	-	-
Hypoglycaemia at admission	3.18 [2.21 - 4.58]	< 0.001	2.76 [1.87 - 4.06]	< 0.001
Deep breathing	1.46 [1.06 - 1.99]	0.02	0.96 [0.67 - 1.36]	0.80
Severe anaemia	1.91 [1.36 - 2.69]	< 0.001	1.57 [1.08 - 2.29]	0.02
Temperature Gradient	2.10 [1.51 - 2.92]	< 0.001	1.77 [1.22 - 2.57]	0.003
Delayed Capillary refill time	1.63 [1.15 - 2.31]	0.006	1.00 [0.65 - 1.55]	0.98
Visible wasting	1.78 [0.98 - 3.25]	0.06	1.32 [0.69 - 2.54]	0.40
Prostration	0.88 [0.64 - 1.20]	0.41	-	-
Weak pulse volume	1.63 [1.11 - 2.41]	0.01	0.93 [0.58 - 1.49]	0.75
Parasitaemia ^#	1.29 [0.86 - 1.95]	0.22	-	-

*Adjusted for age in months; OR - Odds ratio; CI - Confidence Interval.
Treatment, prostration and parasitaemia not included in the multivariable model as p > 0.15
^#Parasitaemia was categorised as below or above 5000 parasites/microlitre

ISSN: 1471-2334