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Table 2 Animals challenged (0.1 or 1.0 ID50) and infected after pre-treatment with test agent or PBS

From: Microbicide excipients can greatly increase susceptibility to genital herpes transmission in the mouse

Agent administered 12 h before viral challenge

Challenge dose 0.1 ID50

Challenge dose 1.0 ID50

Fold-increase susceptibility

GML in K-Y Warming Jelly

21/40 (53%)

*

10

K-Y Warming Jelly

18/39 (46%)

*

7

PBS

*

21/40 (53%)

Reference

  1. *The exposures at challenge doses in these cells were not performed concurrently with the experiment reported in this Table, but results from previously performed experiments at these doses are shown in Table 1 and Fig. 1.
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BMC Infectious Diseases

ISSN: 1471-2334

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