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Table 4 Biochemial Characterization of 14-P4 clonal plaque isolates.

From: Absence of rapid selection for acyclovir or penciclovir resistance following suboptimal oral prodrug therapy of HSV-infected mice

Clone

14-P4A

14-P4B

14-P4C

14-P4D

14-P4E

WT SC16

TK activity

0.3%

0.4%

0.5%

0.3%

0.3%

100%

PCV IC50

>25 μg/ml

>25 μg/ml

>25 μg/ml

>25 μg/ml

>25 μg/ml

0.3 μg/ml

PFA IC50

48 μg/ml

62 μg/ml

55 μg/ml

80 μg/ml

55 μg/ml

64 μg/ml