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  1. Geohelminth infections are highly prevalent infectious diseases of childhood in many regions of the Tropics, and are associated with significant morbidity especially among pre-school and school-age children. T...

    Authors: Philip J Cooper, Martha E Chico, Irene Guadalupe, Carlos A Sandoval, Edward Mitre, Thomas AE Platts-Mills, Mauricio L Barreto, Laura C Rodrigues, David P Strachan and George E Griffin
    Citation: BMC Infectious Diseases 2011 11:184
    Content type: Study protocol Published on:

  2. The chemotherapy used to treat lung cancer causes febrile neutropenia in 10 to 40% of patients. Although most episodes are of undetermined origin, an infectious etiology can be suspected in 30% of cases. In vi...

    Authors: Jean-Philippe Lanoix, Emilie Pluquet, Francois Xavier Lescure, Houcine Bentayeb, Emmanuelle Lecuyer, Marie Boutemy, Patrick Dumont, Vincent Jounieaux, Jean Luc Schmit, Charles Dayen and Youcef Douadi
    Citation: BMC Infectious Diseases 2011 11:183
    Content type: Research article Published on:

  3. Clinical evolution of HIV-infected children who have not yet initiated antiretroviral treatment (ART) is poorly understood in Africa. We describe severe morbidity and mortality of untreated HIV-infected children.

    Authors: Sophie Desmonde, Patrick Coffie, Edmond Aka, Clarisse Amani-Bosse, Eugène Messou, François Dabis, Ahmadou Alioum, Andrea Ciaranello and Valériane Leroy
    Citation: BMC Infectious Diseases 2011 11:182
    Content type: Research article Published on:

  4. The emergence of multi-drug resistant Gram-negatives (MDRGNs) coupled with an alarming scarcity of new antibiotics has forced the optimization of the therapeutic potential of available antibiotics. To exploit ...

    Authors: Pranita D Tamma, Nirupama Putcha, Yong D Suh, Kyle J Van Arendonk and Michael L Rinke
    Citation: BMC Infectious Diseases 2011 11:181
    Content type: Research article Published on:

  6. The knowledge on type specificity and factors that increase or decrease the risk of incident HPV-infections is important to better understand the dynamics of HPV-infections.

    Authors: Karolina Louvanto, Marjut A Rintala, Kari J Syrjänen, Seija E Grénman and Stina M Syrjänen
    Citation: BMC Infectious Diseases 2011 11:179
    Content type: Research article Published on:

  7. Complex mutants can be selected under sequential selective pressure by HBV therapy. To determine hepatitis B virus genomic evolution during antiviral therapy we characterized the HBV quasi-species in a patient...

    Authors: Lucila Cassino, Silvina Benetti, Fabian Fay, Hugo Tanno and Jorge Quarleri
    Citation: BMC Infectious Diseases 2011 11:178
    Content type: Case report Published on:

  8. The effect of peginterferon and ribavirin treatment on chronic hepatitis C virus (HCV) infection has been established in several controlled clinical studies. However, the effectiveness of treatment and predict...

    Authors: Nanna Hansen, Niels Obel, Peer B Christensen, Mette Kjær, Alex L Laursen, Henrik B Krarup, Axel Møller, Poul Schlichting, Jens Bukh and Nina Weis
    Citation: BMC Infectious Diseases 2011 11:177
    Content type: Research article Published on:

  9. Hepatitis B is an important public health problem in the Pakistani population and is the major cause of chronic hepatitis, cirrhosis, fibrosis and hepatocellular carcinoma. High prevalence of HBV infections ha...

    Authors: Fawad Khan, Haji Akbar, Muhammad Idrees, Hayat Khan, Khuram Shahzad and Mahmood A Kayani
    Citation: BMC Infectious Diseases 2011 11:176
    Content type: Research article Published on:

  10. Although Haemophilus influenzae type b (Hib), Staphylococcus aureus and Moraxella catarrhalis are important causes of invasive and mucosal bacterial disease among children, co-carriage with Streptococcus pneumoni...

    Authors: Brenda A Kwambana, Michael R Barer, Christian Bottomley, Richard A Adegbola and Martin Antonio
    Citation: BMC Infectious Diseases 2011 11:175
    Content type: Research article Published on:

  11. Immunization policymakers at global and local levels need to establish priorities among new vaccines competing for limited resources. However, comparison of the potential impact of single vaccination programs ...

    Authors: Sun-Young Kim, Steven Sweet, Joshua Chang and Sue J Goldie
    Citation: BMC Infectious Diseases 2011 11:174
    Content type: Research article Published on:

  12. Herpes zoster (HZ) is caused by a reactivation of the varicella-zoster-virus (VZV) and mainly affects individuals aged ≥ 50 years. Vaccines have been licensed or are under development that can protect against ...

    Authors: Bernhard Ultsch, Anette Siedler, Thorsten Rieck, Thomas Reinhold, Gérard Krause and Ole Wichmann
    Citation: BMC Infectious Diseases 2011 11:173
    Content type: Research article Published on:

  14. Tropheryma whipplei, the agent of Whipple's disease, causes localised infections in the absence of histological digestive involvement. Our objective is to describe T. whipplei encephalitis.

    Authors: Florence Fenollar, François Nicoli, Claire Paquet, Hubert Lepidi, Patrick Cozzone, Jean-Christophe Antoine, Jean Pouget and Didier Raoult
    Citation: BMC Infectious Diseases 2011 11:171
    Content type: Research article Published on:

  15. Antigenic variation of influenza virus necessitates annual reformulation of seasonal influenza vaccines, which contain two type A strains (H1N1 and H3N2) and one type B strain. We used a test negative case con...

    Authors: James E Fielding, Kristina A Grant, Georgina Papadakis and Heath A Kelly
    Citation: BMC Infectious Diseases 2011 11:170
    Content type: Research article Published on:

  16. Helminth infection rates in grade three children are used as proxy indicators of community infection status and to guide treatment strategies in endemic areas. However knowledge, attitudes and practices (KAP) ...

    Authors: Nicholas Midzi, Sekesai Mtapuri-Zinyowera, Munyaradzi P Mapingure, Noah H Paul, Davison Sangweme, Gibson Hlerema, Masceline J Mutsaka, Farisai Tongogara, Godfrey Makware, Vivian Chadukura, Kimberly C Brouwer, Francisca Mutapi, Nirbhay Kumar and Takafira Mduluza
    Citation: BMC Infectious Diseases 2011 11:169
    Content type: Research article Published on:

  17. Recent studies strongly suggest that some respiratory viruses are associated with the induction of acute wheezing and/or exacerbation of bronchial asthma. However, molecular epidemiology of these viruses is no...

    Authors: Asako Fujitsuka, Hiroyuki Tsukagoshi, Mika Arakawa, Kazuko Goto-Sugai, Akihide Ryo, Yoshimichi Okayama, Katsumi Mizuta, Atsuyoshi Nishina, Masakazu Yoshizumi, Yoichi Kaburagi, Masahiro Noda, Masato Tashiro, Nobuhiko Okabe, Masaaki Mori, Shumpei Yokota and Hirokazu Kimura
    Citation: BMC Infectious Diseases 2011 11:168
    Content type: Research article Published on:

  18. Tick-borne lymphadenopathy (TIBOLA) was first described in 1997 in a patient in France. The causative agent, Rickettsia slovaca, is transmitted by Dermacentor ticks.

    Authors: Siegbert Rieg, Sabine Schmoldt, Christian Theilacker, Katja de With, Silke Wölfel, Winfried V Kern and Gerhard Dobler
    Citation: BMC Infectious Diseases 2011 11:167
    Content type: Case report Published on:

  19. During the last decades, dengue viruses have spread throughout the Americas region, with an increase in the number of severe forms of dengue. The surveillance system in Guadeloupe (French West Indies) is curre...

    Authors: Myriam Gharbi, Philippe Quenel, Joël Gustave, Sylvie Cassadou, Guy La Ruche, Laurent Girdary and Laurence Marrama
    Citation: BMC Infectious Diseases 2011 11:166
    Content type: Research article Published on:

  20. Interferon alpha (IFNα) therapy has been widely used in the treatment of chronic hepatitis B (CHB) for decades. Nucleos(t)ide analogues are also increasingly used to treat CHB recently. More and more studies a...

    Authors: Wen-cong Li, Mao-rong Wang, Ling-bo Kong, Wei-guang Ren, Yu-guo Zhang and Yue-min Nan
    Citation: BMC Infectious Diseases 2011 11:165
    Content type: Research article Published on:

  21. Dengue fever is a mosquito-borne disease that affects between 50 and 100 million people each year. Increasing our understanding of the heterogeneous transmission patterns of dengue at different spatial scales ...

    Authors: Gerardo Chowell, Bernard Cazelles, Hélène Broutin and Cesar V Munayco
    Citation: BMC Infectious Diseases 2011 11:164
    Content type: Research article Published on:

  22. As the most common invasive fungal infection, invasive aspergillosis (IA) remains a serious complication in immunocompromised patients, leading to increased mortality. Antifungal therapy is expensive and may r...

    Authors: Karolin Graf, Somayeh Mohammad Khani, Ella Ott, Frauke Mattner, Petra Gastmeier, Dorith Sohr, Stefan Ziesing and Iris F Chaberny
    Citation: BMC Infectious Diseases 2011 11:163
    Content type: Research article Published on:

  23. Mycoplasma pneumoniae infection is usually self-limited, but some fulminant cases are fatal, even when occurring in previously healthy individuals. It can also be the cause of overwhelming postsplenectomy infect...

    Authors: Feng Xu, Chao-Liu Dai, Xing-Mao Wu and Peng Chu
    Citation: BMC Infectious Diseases 2011 11:162
    Content type: Case report Published on:

  24. Acute otitis media with perforation (AOMwiP) affects 40% of remote Indigenous children during the first 18 months of life. Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis are the primar...

    Authors: Michael J Binks, Allen C Cheng, Heidi Smith-Vaughan, Theo Sloots, Michael Nissen, David Whiley, Joseph McDonnell and Amanda J Leach
    Citation: BMC Infectious Diseases 2011 11:161
    Content type: Research article Published on:

  25. In the United States, about 70% of 2.9-3.7 million people with hepatitis C (HCV) are unaware of their infection. Although universal screening might be a cost-effective way to identify infections, prevent morbi...

    Authors: Phillip O Coffin, Anne M Stevens, John D Scott, Joanne D Stekler and Matthew R Golden
    Citation: BMC Infectious Diseases 2011 11:160
    Content type: Research article Published on:

  26. Syphilis is a chronic infection that is classified into three stages. In its tertiary stage, syphilis spreads to the brain, heart and other organs; the lesions may involve the skin, mucous membranes and bones....

    Authors: Lorenzo Drago, Elena De Vecchi, Marco Pasqualini, Laura Moneghini and Maurilio Bruno
    Citation: BMC Infectious Diseases 2011 11:159
    Content type: Case report Published on:

  27. To determine whether chlamydia positivity among heterosexual men (MSW) and chlamydia and gonorrhea positivity among men who have sex with men (MSM), are changing.

    Authors: Lenka A Vodstrcil, Christopher K Fairley, Glenda Fehler, David Leslie, Jennifer Walker, Catriona S Bradshaw and Jane S Hocking
    Citation: BMC Infectious Diseases 2011 11:158
    Content type: Research article Published on:

  28. Compared to the civilian population, military trainees are often at increased risk for respiratory infections. We investigated an outbreak of radiologically-confirmed pneumonia that was recognized after 2 fata...

    Authors: Fatimah S Dawood, John F Ambrose, Bruce P Russell, Anthony W Hawksworth, Jonas M Winchell, Nina Glass, Kathleen Thurman, Michele A Soltis, Erin McDonough, Agnes K Warner, Emily Weston, Nakia S Clemmons, Jennifer Rosen, Stephanie L Mitchell, Dennis J Faix, Patrick J Blair…
    Citation: BMC Infectious Diseases 2011 11:157
    Content type: Research article Published on:

  29. Understanding of the transmission dynamics of tuberculosis (TB) in high TB and HIV prevalent settings is required in order to develop effective intervention strategies for TB control. However, there are little...

    Authors: Keren Middelkoop, Linda-Gail Bekker, Hua Liang, Lisa DH Aquino, Elaine Sebastian, Landon Myer and Robin Wood
    Citation: BMC Infectious Diseases 2011 11:156
    Content type: Research article Published on:

  30. Herpes Simplex Virus type 2 (HSV-2) has public health importance as a leading cause of genital ulcers, a co-factor in HIV-1 acquisition and transmission and as a cause of neonatal herpes infections. Little is ...

    Authors: Joyce U Nyiro, Eduard J Sanders, Caroline Ngetsa, Steve Wale, Ken Awuondo, Elizabeth Bukusi, Matthew A Price, Pauli N Amornkul and D James Nokes
    Citation: BMC Infectious Diseases 2011 11:155
    Content type: Research article Published on:

  31. Helicobacter pylori is a widely spread bacterium that mainly inhabits the gastric mucosa and can lead to serious illnesses such as peptic ulcer disease, gastric carcinoma and gastric MALT lymphoma. The oral-oral...

    Authors: Claudia Peters, Anja Schablon, Melanie Harling, Claudia Wohlert, José Torres Costa and Albert Nienhaus
    Citation: BMC Infectious Diseases 2011 11:154
    Content type: Research article Published on:

  32. Norway is classified as a low prevalence country for hepatitis B virus infection. Vaccination is only recommended for risk groups (intravenous drug users (IDUs), Men who have Sex with Men (MSM), immigrants and...

    Authors: Gražina Rimšelienė, Øivind Nilsen, Hilde Kløvstad, Hans Blystad and Preben Aavitsland
    Citation: BMC Infectious Diseases 2011 11:153
    Content type: Research article Published on:

  33. Emergence of daptomycin-nonsusceptible (DNS) Staphylococcus aureus is a dreadful problem in the treatment of endocarditis. Few current therapeutic agents are effective for treating infections caused by DNS S. aur...

    Authors: Liang-Yu Chen, Cheng-Hsiung Huang, Shu-Chen Kuo, Chen-Yuan Hsiao, Mei-Lin Lin, Fu-Der Wang and Chang-Phone Fung
    Citation: BMC Infectious Diseases 2011 11:152
    Content type: Case report Published on:

  34. MedSense is an electronic hand hygiene compliance monitoring system that provides Infection Control Practitioners with continuous access to hand hygiene compliance information by monitoring Moments 1 and 4 of ...

    Authors: Vincent CC Cheng, Josepha WM Tai, Sara KY Ho, Jasper FW Chan, Kwan Ngai Hung, Pak Leung Ho and Kwok Yung Yuen
    Citation: BMC Infectious Diseases 2011 11:151
    Content type: Research article Published on:

  35. A study including 166 subjects was performed to investigate the frequency and persistence over a 6-month interval of concurrent oral and anal Human Papillomavirus (HPV) infections in Human Immunodeficiency Vir...

    Authors: Saverio G Parisi, Mario Cruciani, Renzo Scaggiante, Caterina Boldrin, Samantha Andreis, Federico Dal Bello, Silvana Pagni, Andrea Barelli, Andrea Sattin, Carlo Mengoli and Giorgio Palù
    Citation: BMC Infectious Diseases 2011 11:150
    Content type: Research article Published on:

  36. Infection caused by Streptococcus agalactiae, a Group B streptococcus, is an emerging disease in non-pregnant adults. This study describes the epidemiological, clinical, and microbiological characteristics of S. ...

    Authors: Romanee Chaiwarith, Waree Jullaket, Manasanant Bunchoo, Nontakan Nuntachit, Thira Sirisanthana and Khuanchai Supparatpinyo
    Citation: BMC Infectious Diseases 2011 11:149
    Content type: Research article Published on:

  38. Typhoid fever remains a significant health problem in many developing countries. A rapid test with a performance comparable to that of blood culture would be highly useful. A rapid diagnostic test for typhoid ...

    Authors: Benedikt Ley, Kamala Thriemer, Shaali M Ame, George M Mtove, Lorenz von Seidlein, Ben Amos, Ilse CE Hendriksen, Abraham Mwambuli, Aikande Shoo, Deok R Kim, Leon R Ochiai, Michael Favorov, John D Clemens, Harald Wilfing, Jacqueline L Deen and Said M Ali
    Citation: BMC Infectious Diseases 2011 11:147
    Content type: Research article Published on:

  39. Viral reservoir size refers to cellular human immunodeficiency virus-1 (HIV-1) DNA levels in CD4+ T lymphocytes of peripheral blood obtained from patients with plasma HIV-1-RNA levels (viral load, VL) maintained ...

    Authors: Dai Watanabe, Shiro Ibe, Tomoko Uehira, Rumi Minami, Atsushi Sasakawa, Keishiro Yajima, Hitoshi Yonemoto, Hiroki Bando, Yoshihiko Ogawa, Tomohiro Taniguchi, Daisuke Kasai, Yasuharu Nishida, Masahiro Yamamoto, Tsuguhiro Kaneda and Takuma Shirasaka
    Citation: BMC Infectious Diseases 2011 11:146
    Content type: Research article Published on:

  40. Patients with rheumatic diseases including rheumatoid arthritis (RA) are at increased risk for infections related to both the disease and its treatments. These include uncommonly reported infections due to his...

    Authors: Timothy C Olson, Tim Bongartz, Cynthia S Crowson, Glenn D Roberts, Robert Orenstein and Eric L Matteson
    Citation: BMC Infectious Diseases 2011 11:145
    Content type: Research article Published on:

  41. Unwanted pregnancy and HIV infection are issues of significant concern to young people. Limited data exists on contraceptive decision-making and practices among HIV-infected and HIV-negative young people in lo...

    Authors: Jolly Beyeza-Kashesya, Frank Kaharuza, Anna Mia Ekström, Stella Neema, Asli Kulane and Florence Mirembe
    Citation: BMC Infectious Diseases 2011 11:144
    Content type: Research article Published on:

  42. About 90% of all malaria deaths in sub-Saharan Africa occur in children under five years. Fast and reliable diagnosis of malaria requires confirmation of the presence of malaria parasites in the blood of patie...

    Authors: Bernard Nkrumah, Samuel EK Acquah, Lukeman Ibrahim, Juergen May, Norbert Brattig, Egbert Tannich, Samuel Blay Nguah, Yaw Adu-Sarkodie and Frank Huenger
    Citation: BMC Infectious Diseases 2011 11:143
    Content type: Research article Published on:

  43. Hantaviruses are the causative agents of two zoonotic diseases: hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). The pathogenesis of HFRS is poorly understood. Howev...

    Authors: Ana Saksida, Branka Wraber and Tatjana Avšič-Županc
    Citation: BMC Infectious Diseases 2011 11:142
    Content type: Research article Published on:

  44. The World Health Organization recommends universal and quality-controlled screening of blood donations for the major transfusion-transmissible infections (TTIs): human immunodeficiency virus (HIV), hepatitis B...

    Authors: Jocelijn Stokx, Philippe Gillet, Anja De Weggheleire, Esther C Casas, Rosa Maendaenda, Adelino J Beulane, Ilhes V Jani, Solon Kidane, Carla D Mosse, Jan Jacobs and Emmanuel Bottieau
    Citation: BMC Infectious Diseases 2011 11:141
    Content type: Research article Published on:

  45. The first influenza pandemic of the 21th century was ignited by a new strain of influenza A virus (A/H1N1pdm). Specific patient groups, including those with comorbidities, pregnant women, young children, older...

    Authors: Silvia Meschi, Marina Selleri, Eleonora Lalle, Licia Bordi, Maria B Valli, Federica Ferraro, Giuseppe Ippolito, Nicola Petrosillo, Francesco N Lauria and Maria R Capobianchi
    Citation: BMC Infectious Diseases 2011 11:140
    Content type: Research article Published on:

  46. Comparison of mortality among patients with positive and negative blood cultures may indicate the contribution of bacteremia to mortality. This study (1) compared mortality among patients with community-acquir...

    Authors: Mette Søgaard, Mette Nørgaard, Lars Pedersen, Henrik T Sørensen and Henrik C Schønheyder
    Citation: BMC Infectious Diseases 2011 11:139
    Content type: Research article Published on:

  47. During the past two decades, methicillin-resistant Staphylococcus aureus (MRSA) has become increasingly common as a source of nosocomial infections. Most studies of MRSA surveillance were performed during outbrea...

    Authors: Madeleine Dulon, Frank Haamann, Claudia Peters, Anja Schablon and Albert Nienhaus
    Citation: BMC Infectious Diseases 2011 11:138
    Content type: Research article Published on:

  48. Reports of the etiology of bacteremia in children from Nigeria are sparse and have been confounded by wide spread non-prescription antibiotic use and suboptimal laboratory culture techniques. We aimed to deter...

    Authors: Stephen Obaro, Lovett Lawson, Uduak Essen, Khalid Ibrahim, Kevin Brooks, Adekunle Otuneye, Denis Shetima, Patience Ahmed, Theresa Ajose, Michael Olugbile, David Idiong, Damola Ogundeji, Comfort Ochigbo, Grace Olanipekun, Walid Khalife and Richard Adegbola
    Citation: BMC Infectious Diseases 2011 11:137
    Content type: Research article Published on:

  49. Persistent neutrophilic meningitis is an unusual form of chronic meningitis that is defined as clinical meningitis with a neutrophilic pleocytosis that persists for greater than 7 days despite empiric antimicr...

    Authors: Jaime S Green, Shira R Abeles, Daniel Z Uslan and Sanjay R Mehta
    Citation: BMC Infectious Diseases 2011 11:136
    Content type: Case report Published on:

  50. There is an urgent need of prognosis markers for tuberculosis (TB) to improve treatment strategies. The results of several studies show that the Interferon (IFN)-γ-specific response to the TB antigens of the Q...

    Authors: Basirudeen Syed Ahamed Kabeer, Alamelu Raja, Balambal Raman, Satheesh Thangaraj, Marc Leportier, Giuseppe Ippolito, Enrico Girardi, Philippe Henri Lagrange and Delia Goletti
    Citation: BMC Infectious Diseases 2011 11:135
    Content type: Research article Published on:

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