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  1. This Phase 3, open-label, rollover study (NCT01323244) investigated the efficacy and safety of simeprevir plus peginterferon α-2a (PegIFNα-2a) and ribavirin (RBV) in a well-characterized population of HCV geno...

    Authors: Edward J. Gane, Edwin DeJesus, Ewa Janczewska, Jacob George, Moises Diago, Mariliza Hendrique Da Silva, Henk Reesink, Igor Nikitin, Holger Hinrichsen, Stefan Bourgeois, Peter Ferenci, Umesh Shukla, Ronald Kalmeijer, Oliver Lenz, Bart Fevery, Chris Corbett…
    Citation: BMC Infectious Diseases 2017 17:389
    Content type: Research article Published on:

  2. Patient screening at the time of hospital admission is not recommended as a routine practice, but may be an important strategy for containment of Clostridium difficile infection (CDI) in hospital settings. We sou...

    Authors: Sara Maghdoori and Seyed M. Moghadas
    Citation: BMC Infectious Diseases 2017 17:384
    Content type: Research article Published on:

  3. Host-level influenza virus–respiratory pathogen interactions are often reported. Although the exact biological mechanisms involved remain unelucidated, secondary bacterial infections are known to account for a...

    Authors: Hélène Arduin, Matthieu Domenech de Cellès, Didier Guillemot, Laurence Watier and Lulla Opatowski
    Citation: BMC Infectious Diseases 2017 17:382
    Content type: Research article Published on:

  4. A rare phenotype of clinical non-progressors to AIDS is not well understood and the new protocol for universal treatment, may block the understanding of viral control thus it is crucial to define this controve...

    Authors: Samara Tatielle M. Gomes, Érica R. Gomes, Mike B. dos Santos, Sandra S. Lima, Maria Alice F. Queiroz, Luiz Fernando A. Machado, Izaura M. V. Cayres-Vallinoto, Antonio Carlos R. Vallinoto, Marluísa de O. Guimarães Ishak and Ricardo Ishak
    Citation: BMC Infectious Diseases 2017 17:381
    Content type: Research article Published on:

  6. Drug-resistant tuberculosis, especially multidrug-resistant tuberculosis (MDR-TB), is a major public health problem. Effective management of MDR-TB relies on accurate and rapid diagnosis. In this study, we ass...

    Authors: Ngu Njei Abanda, Josiane Yvonne Djieugoué, Eunjung Lim, Eric Walter Pefura-Yone, Wilfred Fon Mbacham, Guy Vernet, Veronique Mbeng Penlap, Sara Irene Eyangoh, Diane Wallace Taylor and Rose Gana Fomban Leke
    Citation: BMC Infectious Diseases 2017 17:379
    Content type: Research article Published on:

  7. Harris County, Texas is the third most populous county in the United States and consistently has tuberculosis rates above the national average. Understanding jurisdictional epidemiologic characteristics for th...

    Authors: Saroochi Agarwal, Duc T. Nguyen, Larry D. Teeter and Edward A. Graviss
    Citation: BMC Infectious Diseases 2017 17:378
    Content type: Research article Published on:

  8. Group B Streptococcus (GBS) is a cause of neonatal sepsis, pneumonia, and meningitis that can lead to neurological sequelae in infants less than 3 months of age. The GBS disease burden is not known in China, t...

    Authors: Wenjing Ji, Haiying Liu, Zhengjiang Jin, Aimin Wang, Xiaoping Mu, Xiaosong Qin, Weidong Wang, Chunyan Gao, Yuning Zhu, Xiaodan Feng, Jine Lei, Shangyang She, Lan Jiang, Jing Liu, Shuhua Yang, Zeshi Liu…
    Citation: BMC Infectious Diseases 2017 17:377
    Content type: Study protocol Published on:

  9. Bacterial vaginosis (BV) has been found to be associated with HIV acquisition and transmission.

    Authors: Maria Wessman, Kristina Thorsteinsson, Jørgen S. Jensen, Merete Storgaard, Frederikke F. Rönsholt, Isik S. Johansen, Gitte Pedersen, Lars Nørregård Nielsen, Jesper Bonde, Terese L. Katzenstein, Nina Weis and Anne-Mette Lebech
    Citation: BMC Infectious Diseases 2017 17:376
    Content type: Research article Published on:

  10. The inhibition of gastric acid secretion with ranitidine is frequently prescribed off-label to newborns admitted to neonatal intensive care units (NICU). Some studies show that the use of inhibitors of gastric...

    Authors: Ruth N. S. Santana, Victor S. Santos, Ruy F. Ribeiro-Júnior, Marina S. Freire, Maria A. S. Menezes, Rosana Cipolotti and Ricardo Q. Gurgel
    Citation: BMC Infectious Diseases 2017 17:375
    Content type: Research article Published on:

  11. Multidrug-resistant and rifampicin-resistant tuberculosis (MDR/RR-TB) represent an important challenge for global tuberculosis (TB) control. The high rates of MDR/RR-TB observed among re-treatment cases can ar...

    Authors: Romain Ragonnet, James M. Trauer, Justin T. Denholm, Ben J. Marais and Emma S. McBryde
    Citation: BMC Infectious Diseases 2017 17:374
    Content type: Correspondence Published on:

  12. Tuberculosis is the most frequent opportunistic infection and the leading cause of death among persons living with HIV in several low and middle-income countries. Mortality rates during tuberculosis treatment ...

    Authors: Rodrigo Otavio da Silva Escada, Luciane Velasque, Sayonara Rocha Ribeiro, Sandra Wagner Cardoso, Luana Monteiro Spindola Marins, Eduarda Grinsztejn, Maria Cristina da Silva Lourenço, Beatriz Grinsztejn and Valdiléa Gonçalves Veloso
    Citation: BMC Infectious Diseases 2017 17:373
    Content type: Research article Published on:

  13. Catheter-related bloodstream infections (CRBSIs) are associated with high morbidity and mortality as well as increased medical costs. Cancer patients, who are often immunocompromised, are susceptible to CRBSI ...

    Authors: Pankaj G. Vashi, Natasha Virginkar, Brenten Popiel, Persis Edwin and Digant Gupta
    Citation: BMC Infectious Diseases 2017 17:372
    Content type: Research article Published on:

  14. The clonal spread of multiple drug-resistant Acinetobacter baumannii is an emerging problem in China. We analysed the molecular epidemiology of Acinetobacter baumanni isolates at three teaching hospitals and inve...

    Authors: Yu jun Li, Chu zhi Pan, Chang quan Fang, Zhu xiang Zhao, Hui ling Chen, Peng hao Guo and Zi wen Zhao
    Citation: BMC Infectious Diseases 2017 17:371
    Content type: Research article Published on:

  15. The IFI27 interferon gene expression has been found to be largely increased in rotavirus (RV)-infected patients. IFI27 gene encodes for a protein of unknown function, very recently linked to epidermal proliferati...

    Authors: J. Gómez-Rial, M. J. Curras-Tuala, C. Talavero-González, C. Rodríguez-Tenreiro, L. Vilanova-Trillo, A. Gómez-Carballa, I. Rivero-Calle, A. Justicia-Grande, J. Pardo-Seco, L. Redondo-Collazo, A. Salas and F. Martinón-Torres
    Citation: BMC Infectious Diseases 2017 17:370
    Content type: Research article Published on:

  16. Cryptococcus neoformans is frequently present as an opportunistic pathogen mainly affecting immunocompromised populations. Disseminated C. neoformans infection in immunocompetent popul...

    Authors: Qiaoling Ruan, Yimin Zhu, Shu Chen, Liping Zhu, Shu Zhang and Wenhong Zhang
    Citation: BMC Infectious Diseases 2017 17:369
    Content type: Case report Published on:

  18. The international spread of wild poliomyelitis outbreaks continues to threaten eradication of poliomyelitis and in 2014 a public health emergency of international concern was declared. Here we describe a risk ...

    Authors: Kathleen M. O’Reilly, Christine Lamoureux, Natalie A. Molodecky, Hil Lyons, Nicholas C. Grassly and Graham Tallis
    Citation: BMC Infectious Diseases 2017 17:367
    Content type: Research article Published on:

  19. Antimicrobial resistance (AMR) and genetic determinants of resistance of N. gonorrhoeae isolates from Hefei, China, were characterized adding a breadth of information to the molecular epidemiology of gonococcal r...

    Authors: Fa-Xing Jiang, Qian Lan, Wen-Jing Le and Xiao-Hong Su
    Citation: BMC Infectious Diseases 2017 17:366
    Content type: Research article Published on:

  20. Foreign-born patients with tuberculosis (TB) may introduce globally disseminated isolates of Mycobacterium tuberculosis into large cities in Japan. The risk of dissemination of these isolates into local regions, ...

    Authors: Fuminori Mizukoshi, Tohru Miyoshi-Akiyama, Hiroki Iwai, Takako Suzuki, Reiko Kiritani, Teruo Kirikae and Keiji Funatogawa
    Citation: BMC Infectious Diseases 2017 17:365
    Content type: Research article Published on:

  21. In Vietnam, no systematic prenatal toxoplasmosis screening is in place, and only few studies have assessed the prevalence and importance of this zoonotic parasite infection. In addition, no studies have been c...

    Authors: G. Suzanne A. Smit, Thi Lam Binh Vu, Trung Dung Do, Niko Speybroeck, Brecht Devleesschauwer, Elizaveta Padalko, Ellen Roets and Pierre Dorny
    Citation: BMC Infectious Diseases 2017 17:364
    Content type: Study protocol Published on:

  23. Intestinal parasitic infections are still one of the major health concerns in developing countries. Monitoring of intestinal parasitic infection and associated risk factors are essential for intervention strat...

    Authors: Tamirat Hailegebriel
    Citation: BMC Infectious Diseases 2017 17:362
    Content type: Research article Published on:

  24. There is a need for validation of noninvasive alternatives to liver biopsy for the evaluation of fibrosis in children with chronic hepatitis C (CHC). The aim of this study was to evaluate the diagnostic perfor...

    Authors: Maria Pokorska-Śpiewak, Barbara Kowalik-Mikołajewska, Małgorzata Aniszewska, Magdalena Pluta and Magdalena Marczyńska
    Citation: BMC Infectious Diseases 2017 17:361
    Content type: Research article Published on:

  25. Bacteraemia is a common cause of morbidity and mortality in patients admitted to hospital. The aim of this study is to analyse the results of a two-year programme for the early optimisation of antibiotic treat...

    Authors: A. del Arco, J. Olalla, J. de la Torre, A. Blázquez, N. Montiel-Quezel, J. L. Prada, F. Rivas, J. García-Alegría and F. Fernández-Sánchez
    Citation: BMC Infectious Diseases 2017 17:360
    Content type: Research article Published on:

  26. Disseminated cryptococcosis is a rare and fatal disease, and limited data exist regarding it in children. This study aimed to investigate the clinical characteristics of disseminated cryptococcosis in previous...

    Authors: Li-Wei Gao, An-Xia Jiao, Xi-Rong Wu, Shun-Ying Zhao, Yun Ma, Gang Liu, Ju Yin, Bao-Ping Xu and Kun-Ling Shen
    Citation: BMC Infectious Diseases 2017 17:359
    Content type: Research article Published on:

  27. Due to the vulnerable nature of its patients, the wide use of invasive devices and broad-spectrum antimicrobials used, the intensive care unit (ICU) is often called the epicentre of infections. In the present ...

    Authors: Carmen Axente, Monica Licker, Roxana Moldovan, Elena Hogea, Delia Muntean, Florin Horhat, Ovidiu Bedreag, Dorel Sandesc, Marius Papurica, Dorina Dugaesescu, Mirela Voicu and Luminita Baditoiu
    Citation: BMC Infectious Diseases 2017 17:358
    Content type: Research article Published on:

  28. Authors: Yao Xiao, Man-Li Tong, Li-Li Liu, Li-Rong Lin, Mei-Jun Chen, Hui-Lin Zhang, Wei-Hong Zheng, Shu-Lian Li, Hui-Ling Lin, Zhi-Feng Lin, Hui-Qin Xing, Jian-Jun Niu and Tian-Ci Yang
    Citation: BMC Infectious Diseases 2017 17:357
    Content type: Erratum Published on:

    The original article was published in BMC Infectious Diseases 2017 17:310

  29. In 2004, universal childhood varicella vaccination was introduced in Germany. We aimed to determine the age-specific prevalence of anti-varicella zoster virus (VZV) IgG-antibodies among children in the pre-var...

    Authors: Miriam Wiese-Posselt, Anette Siedler, Annette Mankertz, Andreas Sauerbrei, Hartmut Hengel, Ole Wichmann and Christina Poethko-Müller
    Citation: BMC Infectious Diseases 2017 17:356
    Content type: Research article Published on:

  30. Authors: Eshan U. Patel, Jordyn Manucci, Erin M. Kahle, Jairam R. Lingappa, Rhoda Ashley Morrow, Estelle Piwowar-Manning, Anelet James, Kwitaka F. Maluzi, Maina M. Cheeba, Glenda Gray, Barry Kosloff, Sinead Delany-Moretlwe, Mubiana Inambao, Bellington Vwalika, Thomas C. Quinn and Oliver Laeyendecker
    Citation: BMC Infectious Diseases 2017 17:355
    Content type: Erratum Published on:

    The original article was published in BMC Infectious Diseases 2015 15:398

  31. In Zambia, 14.2% of adults have HIV/AIDS. There has been a substantial and significant increase in patients hospitalized for ischaemic stroke with co-existing HIV infection. However, little is known about the ...

    Authors: Stanley Zimba, Patrice Mukomena Ntanda, Shabir Lakhi and Masharip Atadzhanov
    Citation: BMC Infectious Diseases 2017 17:354
    Content type: Research article Published on:

  32. Varicella is generally considered a mild disease. Disease burden is not well known and country-level estimation is challenging. As varicella disease is not notifiable, notification criteria and rates vary betw...

    Authors: Margarita Riera-Montes, Kaatje Bollaerts, Ulrich Heininger, Niel Hens, Giovanni Gabutti, Angel Gil, Bayad Nozad, Grazina Mirinaviciute, Elmira Flem, Audrey Souverain, Thomas Verstraeten and Susanne Hartwig
    Citation: BMC Infectious Diseases 2017 17:353
    Content type: Research article Published on:

  33. Ethiopia set an ambitious masterplan to increase chicken meat and egg production from 2015 to 2020. Poultry breeding, multiplication and distribution centers in the country have received executive order to imp...

    Authors: Reta Duguma Abdi, Fisseha Mengstie, Ashenafi Feyisa Beyi, Takele Beyene, Hika Waktole, Bedasso Mammo, Dinka Ayana and Fufa Abunna
    Citation: BMC Infectious Diseases 2017 17:352
    Content type: Research article Published on:

  34. High proportion of TB in people living with HIV (PLHIV) is undiagnosed. Due to this active TB case finding is recommended for HIV clinics in high TB burden countries. Presently sputum examination and chest rad...

    Authors: Sonam Spalgais, Upasna Agarwal, Rohit Sarin, Devesh Chauhan, Anita Yadav and Anand Jaiswal
    Citation: BMC Infectious Diseases 2017 17:351
    Content type: Research article Published on:

  35. Chlorhexidine (CHG) penetrates poorly into skin. The purpose of this study was to compare the depth of CHG skin permeation from solutions containing either 2% (w/v) CHG and 70% (v/v) isopropyl alcohol (IPA) or 2%...

    Authors: A. L. Casey, T. J. Karpanen, B. R. Conway, T. Worthington, P. Nightingale, R. Waters and T. S. J. Elliott
    Citation: BMC Infectious Diseases 2017 17:350
    Content type: Research article Published on:

  36. Kynurenine/Tryptophan ratio (KTR) is increased in HIV infection, and linked to immune activation. We hypothesized that early cART initiation results in lower KTR compared to late initiation. Furthermore, we hy...

    Authors: Marco Gelpi, Hans J. Hartling, Per M. Ueland, Henrik Ullum, Marius Trøseid and Susanne D. Nielsen
    Citation: BMC Infectious Diseases 2017 17:349
    Content type: Research article Published on:

  37. Pertussis, a vaccine preventable disease, is still responsible of significant morbidity and mortality around the world, mostly in newborns. The aim of the present study was (1) to introduce pertussis surveilla...

    Authors: Khalid Katfy, Nicole Guiso, Idrissa Diawara, Khalid Zerouali, Bouchra Slaoui, Zineb Jouhadi, Abdelhadi Zineddine, Houria Belabbes and Naima Elmdaghri
    Citation: BMC Infectious Diseases 2017 17:348
    Content type: Research article Published on:

  38. Whereas high risk groups such as asylum seekers are systematically screened for active tuberculosis (TB) upon entry in Switzerland, this strategy does not apply to homeless persons despite a reported high risk...

    Authors: Jean-Paul Janssens, Timothee Wuillemin, Dan Adler and Yves Jackson
    Citation: BMC Infectious Diseases 2017 17:347
    Content type: Research article Published on:

  39. Human papillomavirus (HPV) is the most common sexually transmitted agent, and it can cause cervical lesions and cancer in females. Currently, information regarding the prevalence of HPV in Cyprus is lacking. T...

    Authors: George Krashias, Dana Koptides and Christina Christodoulou
    Citation: BMC Infectious Diseases 2017 17:346
    Content type: Research article Published on:

  40. Over the past few decades, numerous forecasting methods have been proposed in the field of epidemic forecasting. Such methods can be classified into different categories such as deterministic vs. probabilistic...

    Authors: Farzaneh Sadat Tabataba, Prithwish Chakraborty, Naren Ramakrishnan, Srinivasan Venkatramanan, Jiangzhuo Chen, Bryan Lewis and Madhav Marathe
    Citation: BMC Infectious Diseases 2017 17:345
    Content type: TECHNICAL ADVANCE Published on:

  41. Strains of the Beijing genotype of Mycobacterium tuberculosis (MTB) are reportedly associated with the virulence of tuberculosis (TB) infection, unfavorable outcomes of anti-TB treatment, and the global TB pandem...

    Authors: Jingge Zhao, Takashi Matsuba, Xiaoyan Zhang, Susan Leano, Chie Nakajima, Haorile Chagan-Yasutan, Elizabeth Freda Telan, Yasuhiko Suzuki and Toshio Hattori
    Citation: BMC Infectious Diseases 2017 17:344
    Content type: Research article Published on:

  42. Yellow Fever (YF) is a viral hemorrhagic disease transmitted by aedes mosquito species. Approximately, 200,000 cases and 30,000 deaths occur worldwide every year. In Ethiopia, the last outbreak was reported in 19...

    Authors: Abrham Lilay, Negga Asamene, Abyot Bekele, Mesfin Mengesha, Milliyon Wendabeku, Israel Tareke, Abiy Girmay, Yonas Wuletaw, Abate Adossa, Yamar Ba, Amadou Sall, Daddi Jima and Debritu Mengesha
    Citation: BMC Infectious Diseases 2017 17:343
    Content type: Research article Published on:

  43. Molecular subtyping and enhanced surveillance in Lombardy region identified a cluster of possibly related listeriosis cases from 2006 to 2010. This cluster grouped 31 isolates that belonged to serotype 1/2a an...

    Authors: Ettore Amato, Virginia Filipello, Maria Gori, Sara Lomonaco, Marina Nadia Losio, Antonio Parisi, Pol Huedo, Stephen John Knabel and Mirella Pontello
    Citation: BMC Infectious Diseases 2017 17:342
    Content type: Research article Published on:

  44. Currently, there is limited data on the risk factors associated with treatment delay in tuberculous meningitis (TBM). This study aimed to assess the duration of delay in the treatment TBM and to investigate it...

    Authors: Yu He, Chao Han, Kai-Feng Chang, Mao-Shui Wang and Tian-Ren Huang
    Citation: BMC Infectious Diseases 2017 17:341
    Content type: Research article Published on:

  45. The reason why Cystic Fibrosis (CF) is the most common fatal genetic disease among Caucasians has been incompletely studied. We aimed at deepening the hypothesis that CF carriers have a relative protection aga...

    Authors: Lander Bosch, Barbara Bosch, Kris De Boeck, Tim Nawrot, Isabelle Meyts, Dominique Vanneste, Cleonice Alexandre Le Bourlegat, Julio Croda and Luiz Vicente Ribeiro Ferreira da Silva Filho
    Citation: BMC Infectious Diseases 2017 17:340
    Content type: Research article Published on:

  46. Urine LAM testing has been approved by the WHO for use in hospitalised patients with advanced immunosuppression. However, sensitivity remains suboptimal. We therefore examined the incremental diagnostic sensit...

    Authors: Phindile Gina, Philippa J. Randall, Tapuwa E. Muchinga, Anil Pooran, Richard Meldau, Jonny G. Peter and Keertan Dheda
    Citation: BMC Infectious Diseases 2017 17:339
    Content type: Research article Published on:

  47. Intravaginal practices (IVP) (cleansing or introducing products inside the vagina for hygiene, health or to please sexual partners) are common among women with HIV. IVP increase the risk of developing bacteria...

    Authors: Maria L. Alcaide, Maureen Chisembele, Emeria Malupande, Violeta J. Rodriguez, Margaret A. Fischl, Kristopher Arheart and Deborah L. Jones
    Citation: BMC Infectious Diseases 2017 17:338
    Content type: Research article Published on:

  48. Two subtypes of influenza A currently circulate in humans: seasonal H3N2 (sH3N2, emerged in 1968) and pandemic H1N1 (pH1N1, emerged in 2009). While the epidemiological characteristics of the initial wave of pH...

    Authors: Kin On Kwok, Steven Riley, Ranawaka A. P. M. Perera, Vivian W. I. Wei, Peng Wu, Lan Wei, Daniel K. W. Chu, Ian G. Barr, J. S. Malik Peiris and Benjamin J. Cowling
    Citation: BMC Infectious Diseases 2017 17:337
    Content type: Research article Published on:

  49. Acute respiratory infections (ARI) and acute gastrointestinal infections (AGI) are the most common childhood infections, and corresponding data can either be collected prospectively or retrospectively. The aim...

    Authors: Kristin Maria Schlinkmann, Abhishek Bakuli and Rafael Mikolajczyk
    Citation: BMC Infectious Diseases 2017 17:336
    Content type: Research article Published on:

  50. Authors: Claudia Fortuna, Maria Elena Remoli, Caterina Rizzo, Eleonora Benedetti, Cristiano Fiorentini, Antonino Bella, Claudio Argentini, Francesca Farchi, Concetta Castilletti, Maria Rosaria Capobianchi, Lorenzo Zammarchi, Alessandro Bartoloni, Nadia Zanchetta, Maria Rita Gismondo, Luca Ceccherini Nelli, Giustina Vitale…
    Citation: BMC Infectious Diseases 2017 17:335
    Content type: Erratum Published on:

    The original article was published in BMC Infectious Diseases 2017 17:216

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