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  1. Rift valley fever (RVF) is a re-emerging viral vector-borne disease with rapid global socio-economic impact. A large RVF outbreak occurred in Tanzania in 2007 and affected more than half of the regions with hi...

    Authors: Sasita S. Shabani, Mangi J. Ezekiel, Mohamed Mohamed and Candida S. Moshiro
    Citation: BMC Infectious Diseases 2015 15:363
    Content type: Research article Published on:

  2. Delay in tuberculosis (TB) diagnosis adversely affects patients’ outcomes and prolongs transmission in the community. The influence of social contacts on steps taken by active pulmonary TB patients to seek a d...

    Authors: Juliet N. Sekandi, Sarah Zalwango, Leonardo Martinez, Andreas Handel, Robert Kakaire, Allan K. Nkwata, Amara E. Ezeamama, Noah Kiwanuka and Christopher C. Whalen
    Citation: BMC Infectious Diseases 2015 15:361
    Content type: Research article Published on:

  3. Salmonella enterica serotype Enteritidis (S. Enteritidis) remains a major foodborne pathogen in North America yet studies examining the spatial epidemiology of salmonellosis in urban environments are lacking. Our...

    Authors: Csaba Varga, David L. Pearl, Scott A. McEwen, Jan M. Sargeant, Frank Pollari and Michele T. Guerin
    Citation: BMC Infectious Diseases 2015 15:359
    Content type: Research article Published on:

  4. The importance of multidrug-resistant organisms (MDRO) in Chinese hospitals is not clearly delineated. Thus we sought to assess the prevalence of MDRO in Chinese intensive care units (ICUs).

    Authors: Xiaojun Ma, Yinghong Wu, Liuyi Li, Qian Xu, Bijie Hu, Yuxing Ni, Anhua Wu, Shumei Sun, Vincent Jarlier and Jérôme Robert
    Citation: BMC Infectious Diseases 2015 15:358
    Content type: Research article Published on:

  5. The re-emergence of syphilis among HIV-positive gay and other men who have sex with men (MSM) requires vigilance. We estimated incidence of and risk factors for first and subsequent syphilis diagnoses among MS...

    Authors: Ann N. Burchell, Vanessa G. Allen, Sandra L. Gardner, Veronika Moravan, Darrell H. S. Tan, Ramandip Grewal, Janet Raboud, Ahmed M. Bayoumi, Rupert Kaul, Tony Mazzulli, Frank McGee and Sean B. Rourke
    Citation: BMC Infectious Diseases 2015 15:356
    Content type: Research article Published on:

  6. The link between infection with hepatitis C virus (HCV) and personality disorders (PD) has not been investigated in detail. The aim of this study was to compare the effectiveness of HCV treatment in prisoners ...

    Authors: Andrés Marco, José J. Antón, Joan Trujols, Pablo Saíz de la Hoya, José de Juan, Inmaculada Faraco and Joan A Caylà
    Citation: BMC Infectious Diseases 2015 15:355
    Content type: Research article Published on:

  7. Mycobacterium lentiflavum (M. lentiflavum), a slow growing nontuberculous mycobacterium (NTM), has recently been described as an emerging human pathogen regardless of the immune status of the host. Previous repor...

    Authors: Yong Chul Lee, Seung Bum Kim, Su Jin Gang, Seung Yong Park and So Ri Kim
    Citation: BMC Infectious Diseases 2015 15:354
    Content type: Case report Published on:

  8. As part of the EU funded project “HEPscreen”, the aim of this study is to identify hepatitis B and C screening and patient management guidelines, to assess the awareness of these among health professionals (HP...

    Authors: Angela Bechini, Abby Falla, Amena Ahmad, Irene Veldhuijzen, Sara Boccalini, Barbara Porchia and Miriam Levi
    Citation: BMC Infectious Diseases 2015 15:353
    Content type: Research article Published on:

  9. Cryptococcal meningitis is the most common fungal infection of the central nervous system (CNS) in HIV/AIDS. HIV-1 virotoxins (e.g., gp41) are able to induce disorders of the blood-brain barrier (BBB), which m...

    Authors: Bao Zhang, Jing-Yi Yu, Li-Qun Liu, Liang Peng, Feng Chi, Chun-Hua Wu, Ambrose Jong, Shi-Fu Wang, Hong Cao and Sheng-He Huang
    Citation: BMC Infectious Diseases 2015 15:352
    Content type: Research article Published on:

  11. The objectives of this study were to describe hospital stays related to HZ and to evaluate the direct and indirect cost of hospitalizations due to HZ among patients aged over 50 years.

    Authors: Cecile Blein, Gaetan Gavazzi, Marc Paccalin, Charles Baptiste, Gilles Berrut and Alexandre Vainchtock
    Citation: BMC Infectious Diseases 2015 15:350
    Content type: Research article Published on:

  12. Avahan, a large-scale HIV prevention program in India, transitioned over 130 intervention sites from donor funding and management to government ownership in three rounds. This paper examines the transition exp...

    Authors: Daniela C. Rodríguez, Vandana Tripathi, Meghan Bohren, Amy Paul, Kriti Singh, Vibha Chhabra, Suneeta Singh and Sara Bennett
    Citation: BMC Infectious Diseases 2015 15:349
    Content type: Research article Published on:

  13. Efficacy trials investigating the effect of multivitamin (MV) supplementations among patients on Highly Active Antiretroviral Therapy (HAART) have so far been inconclusive. We conducted a randomized, double bl...

    Authors: David Guwatudde, Molin Wang, Amara E. Ezeamama, Danstan Bagenda, Rachel Kyeyune, Henry Wamani, Yukari C. Manabe and Wafaie W. Fawzi
    Citation: BMC Infectious Diseases 2015 15:348
    Content type: Research article Published on:

  14. Community-acquired-pneumonia is the leading cause of child mortality worldwide. Very few studies have explored the predictive value of Proadrenomedullin and Copeptin in pediatric severe pneumonia and bacteremia.

    Authors: Gabriel Alcoba, Sergio Manzano, Laurence Lacroix, Annick Galetto-Lacour and Alain Gervaix
    Citation: BMC Infectious Diseases 2015 15:347
    Content type: Research article Published on:

  16. Meningoencephalitis is one of the most common disorders of the central nervous system (CNS) worldwide. Viral meningoencephalitis differs from bacterial meningitis in several aspects. In some developing countri...

    Authors: Michele Souza Bastos, Jordana Grazziela Coelho-dos-Reis, Danielle Alves Gomes Zauli, Felipe Gomes Naveca, Rossicleia Lins Monte, João Paulo Pimentel, Valéria Munique Kramer Macário, Natália Lessa da Silva, Vanessa Peruhype-Magalhães, Marcelo Antônio Pascoal-Xavier, Allyson Guimaraes, Andréa Teixeira Carvalho, Adriana Malheiro, Olindo Assis Martins-Filho and Maria Paula Gomes Mourão
    Citation: BMC Infectious Diseases 2015 15:345
    Content type: Research article Published on:

  17. Serum 25-hydroxyvitamin D3 levels are generally lower in chronic hepatitis C patients than in healthy individuals. The purpose of this study is to clarify the factors which affect serum 25-hydroxyvitamin D3 level...

    Authors: Masanori Atsukawa, Akihito Tsubota, Noritomo Shimada, Kai Yoshizawa, Hiroshi Abe, Toru Asano, Yusuke Ohkubo, Masahiro Araki, Tadashi Ikegami, Chisa Kondo, Norio Itokawa, Ai Nakagawa, Taeang Arai, Yoko Matsushita, Katsuhisa Nakatsuka, Tomomi Furihata…
    Citation: BMC Infectious Diseases 2015 15:344
    Content type: Research article Published on:

  19. During early HIV-1 infection (EHI), the interaction between the immune response and the virus determines disease progression. Although CD1c + myeloid dendritic cells (mDCs) can trigger the immune response, the...

    Authors: Yingying Diao, Wenqing Geng, Xuejie Fan, Hualu Cui, Hong Sun, Yongjun Jiang, Yanan Wang, Amy Sun and Hong Shang
    Citation: BMC Infectious Diseases 2015 15:342
    Content type: Research article Published on:

  20. In 2011 the largest measles outbreak in North America in a decade occurred in Quebec, Canada with over 700 cases. In contrast, measles activity in neighbouring province Ontario remained low (8 cases). Our obje...

    Authors: Sarah E. Wilson, Kamran Khan, Vladimir Gilca, Jennifer Miniota, Shelley L. Deeks, Gillian Lim, Rose Eckhardt, Shelly Bolotin and Natasha S. Crowcroft
    Citation: BMC Infectious Diseases 2015 15:341
    Content type: Research article Published on:

  21. Candida parapsilosis was the most common species causing candidemia in the 2010 China Hospital Invasive Fungal Surveillance Net (CHIF-NET) database. Compared to Candida albicans, the description of azole resistan...

    Authors: Li Zhang, Meng Xiao, Matthew R. Watts, He Wang, Xin Fan, Fanrong Kong and Ying-Chun Xu
    Citation: BMC Infectious Diseases 2015 15:340
    Content type: Case report Published on:

  22. Whipple’s disease is a rare, often multisystemic chronic infectious disease caused by the rod-shaped bacterium Tropheryma whipplei. Very rarely the heart is involved in the process of the disease, leading to cult...

    Authors: Anthony Alozie, Annette Zimpfer, Kerstin Köller, Bernd Westphal, Annette Obliers, Andreas Erbersdobler, Gustav Steinhoff and Andreas Podbielski
    Citation: BMC Infectious Diseases 2015 15:339
    Content type: Case report Published on:

  23. Diarrhoea still accounts for considerable mortality and morbidity worldwide. The highest burden is concentrated in tropical areas where populations lack access to clean water, adequate sanitation and hygiene. ...

    Authors: Katja Polman, Sören L. Becker, Emilie Alirol, Nisha K. Bhatta, Narayan R. Bhattarai, Emmanuel Bottieau, Martin W. Bratschi, Sakib Burza, Jean T. Coulibaly, Mama N. Doumbia, Ninon S. Horié, Jan Jacobs, Basudha Khanal, Aly Landouré, Yodi Mahendradhata, Filip Meheus…
    Citation: BMC Infectious Diseases 2015 15:338
    Content type: Study protocol Published on:

    The Erratum to this article has been published in BMC Infectious Diseases 2015 15:499

  24. Human Rhinovirus (HRV) is responsible for the majority of common colds and is frequently accompanied by secondary bacterial infections through poorly understood mechanisms. We investigated the effects of exper...

    Authors: J. J. Hofstra, S. Matamoros, M. A. van de Pol, B. de Wever, M. W. Tanck, H. Wendt-Knol, M. Deijs, L. van der Hoek, K. C. Wolthers, R. Molenkamp, C. E. Visser, P. J. Sterk, R. Lutter and M. D. de Jong
    Citation: BMC Infectious Diseases 2015 15:336
    Content type: Research article Published on:

  25. Hepatitis B virus (HBV) is a major global health problem especially in sub-Saharan Africa and in East Asia. Ten hepatitis B virus genotypes have been described that differ by geographic distribution, disease p...

    Authors: Motswedi Anderson, Simani Gaseitsiwe, Sikhulile Moyo, Matthijs J. C. Wessels, Terence Mohammed, Theresa K. Sebunya, Eleanor A. Powell, Joseph Makhema, Jason T. Blackard, Richard Marlink, Max Essex and Rosemary M. Musonda
    Citation: BMC Infectious Diseases 2015 15:335
    Content type: Research article Published on:

  26. Isoniazid preventive therapy (IPT) is a recommended strategy for prevention of tuberculosis (TB) in persons with Human Immunodeficiency Virus (HIV) although the benefits have not been unequivocally demonstrate...

    Authors: Henok Tadesse Ayele, Maaike SM van Mourik and Marc JM Bonten
    Citation: BMC Infectious Diseases 2015 15:334
    Content type: Research article Published on:

  27. Many neurological diseases are accompanied by an increase in the cerebrospinal fluid (CSF) protein concentration, which indicates dysfunction of the blood-CSF/blood–brain barrier. However, the significance CSF...

    Authors: Liang Huang, Hui Ye, Junyan Qu, Yanbin Liu, Cejun Zhong, Guangmin Tang, Ying Liu, Yao Huang and Xiaoju Lv
    Citation: BMC Infectious Diseases 2015 15:333
    Content type: Research article Published on:

  28. Community acquired pneumonia is a major cause of morbidity and mortality. The association between serum phosphorus levels on admission and the outcome of patients with community acquired pneumonia has not been...

    Authors: Mohammad E. Naffaa, Mona Mustafa, Mohje Azzam, Roni Nasser, Nizar Andria, Zaher S. Azzam and Eyal Braun
    Citation: BMC Infectious Diseases 2015 15:332
    Content type: Research article Published on:

  29. Treating latent tuberculosis infection (LTBI) is an important public health intervention. In the UK, LTBI treatment is delivered in secondary care. Treating LTBI in the community would move care closer to home...

    Authors: Christina Atchison, Dominik Zenner, Lily Barnett and Manish Pareek
    Citation: BMC Infectious Diseases 2015 15:331
    Content type: Research article Published on:

  30. A simple method to estimate CD4 counts in stable, HIV infected virologically-suppressed and immune-reconstituted adults could save the expense of unnecessary formal testing.

    Authors: Barnaby Young, Oon Tek Ng, David Chien Lye and Yee Sin Leo
    Citation: BMC Infectious Diseases 2015 15:330
    Content type: Research article Published on:

  31. Despite consistent recommendations by all Public Health Authorities in support of annual influenza vaccination for at-risk categories, there is still a low uptake of influenza vaccine in these groups including...

    Authors: Antonietta Giannattasio, Miriam Mariano, Roberto Romano, Fabrizia Chiatto, Ilaria Liguoro, Guglielmo Borgia, Alfredo Guarino and Andrea Lo Vecchio
    Citation: BMC Infectious Diseases 2015 15:329
    Content type: Research article Published on:

  32. We established Safeguard the Family (STF) to support Ministry of Health (MoH) scale-up of universal antiretroviral therapy (ART) for HIV-infected pregnant and breastfeeding women (Option B+) and to strengthen ...

    Authors: Michael E. Herce, Tiwonge Mtande, Frank Chimbwandira, Innocent Mofolo, Christine K. Chingondole, Nora E. Rosenberg, Kathy E. Lancaster, Esmie Kamanga, Jacqueline Chinkonde, Wiza Kumwenda, Gerald Tegha, Mina C. Hosseinipour, Irving F. Hoffman, Francis E. Martinson, Eva Stein and Charles M. van der Horst
    Citation: BMC Infectious Diseases 2015 15:328
    Content type: Research article Published on:

  33. Chronic tuberculous empyema (CTE) is a rare and unusual, low grade and protracted, infection of the pleural space resulting in marked thickening, even calcification of the visceral and parietal pleura. Histori...

    Authors: Richard Long, James Barrie and Charles A. Peloquin
    Citation: BMC Infectious Diseases 2015 15:327
    Content type: Case report Published on:

  34. There are few data regarding clinical care and outcomes of Indigenous Australians living with HIV and it is unknown if these differ from non-Indigenous HIV-positive Australians.

    Authors: David J. Templeton, Stephen T. Wright, Hamish McManus, Chris Lawrence, Darren B. Russell, Matthew G. Law and Kathy Petoumenos
    Citation: BMC Infectious Diseases 2015 15:326
    Content type: Research article Published on:

  35. Recently, we introduced a novel peptide nucleic acid (PNA) multi-probe real time PCR method targeting the hsp65 gene (hsp65 PNA RT-PCR) to distinguish Mycobacterium abscessus groups.

    Authors: Kijeong Kim, Seok-Hyun Hong, Byoung-Jun Kim, Bo-Ram Kim, So-Young Lee, Ga-Na Kim, Tae Sun Shim, Yoon-Hoh Kook and Bum-Joon Kim
    Citation: BMC Infectious Diseases 2015 15:325
    Content type: Research article Published on:

  36. Shiga toxin-producing E. coli (STEC) infection is associated with haemolytic uremic syndrome (HUS). Therefore Norway has implemented strict guidelines for prevention and control of STEC infection. However, only a...

    Authors: Lin T. Brandal, Astrid L. Wester, Heidi Lange, Inger Løbersli, Bjørn-Arne Lindstedt, Line Vold and Georg Kapperud
    Citation: BMC Infectious Diseases 2015 15:324
    Content type: Research article Published on:

  37. In the healthcare sector, it is crucial to identify sustainable strategies in order to allow the introduction and use of innovative technologies. Now, and over the next few years, the expiry of patents for dif...

    Authors: Umberto Restelli, Francesca Scolari, Paolo Bonfanti, Davide Croce and Giuliano Rizzardini
    Citation: BMC Infectious Diseases 2015 15:323
    Content type: Research article Published on:

  38. Delay in diagnosis is one of the most important factors for the control of tuberculosis (TB) in endemic countries like India. As laboratory diagnosis is the mainstay for identification of active disease, we ai...

    Authors: Manju Raj Purohit, Megha Sharma, Senia Rosales-Klintz and Cecilia Stålsby Lundborg
    Citation: BMC Infectious Diseases 2015 15:322
    Content type: Research article Published on:

  39. The emerging resistance to the extended-spectrum cephalosporins (ESCs) in Neisseria gonorrhoeae together with increasing incidence of gonorrhoea cases in many countries have been global public health concerns. Ho...

    Authors: Michelle J. Cole, Gianfranco Spiteri, Susanne Jacobsson, Rachel Pitt, Vlad Grigorjev and Magnus Unemo
    Citation: BMC Infectious Diseases 2015 15:321
    Content type: Research article Published on:

  40. Elevated C-reactive protein (CRP) level is widely used in clinical practice as a marker to distinguish between neonates with or without sepsis. However, some neonates with bacteremia have a CRP level within th...

    Authors: Mei-Yin Lai, Ming-Horng Tsai, Chiang-Wen Lee, Ming-Chou Chiang, Reyin Lien, Ren-Huei Fu, Hsuan-Rong Huang, Shih-Ming Chu and Jen-Fu Hsu
    Citation: BMC Infectious Diseases 2015 15:320
    Content type: Research article Published on:

  41. Leptospirosis is often treated based on clinical diagnosis. There is a need for rapid laboratory diagnosis for this condition. The aim of this study was to compare the diagnostic accuracy of two rapid IgM base...

    Authors: Egwin J. Eugene, Shiroma M. Handunnetti, Shalini A. Wickramasinghe, Thilini L. Kalugalage, Chathuraka Rodrigo, Hasith Wickremesinghe, Nandana Dikmadugoda, Pranitha Somaratne, H Janaka De Silva and Senaka Rajapakse
    Citation: BMC Infectious Diseases 2015 15:319
    Content type: Research article Published on:

  42. Guangzhou is the economic center of South China, which is currently suffering an insidious re-emergence of syphilis. Syphilis epidemic in this area is a matter of serious concern, because of the special econom...

    Authors: Wangjian Zhang, Zhicheng Du, Shaokai Tang, Pi Guo, Xingdong Ye and Yuantao Hao
    Citation: BMC Infectious Diseases 2015 15:318
    Content type: Research article Published on:

  43. Cotrimoxazole prophylaxis has an antimalarial effect which could have an additional protective effect against malaria in HIV-infected children on antiretroviral therapy (ART). We measured the incidence and ass...

    Authors: Aïda Mounkaila Harouna, Madeleine Amorissani-Folquet, François Tanoh Eboua, Sophie Desmonde, Sylvie N’Gbeche, Edmond Addi Aka, Kouakou Kouadio, Brou Kouacou, Karen Malateste, Clarisse Bosse-Amani, Patrick Ahuatchi Coffie and Valeriane Leroy
    Citation: BMC Infectious Diseases 2015 15:317
    Content type: Research article Published on:

  44. There has been a clear increase in HIV-1 infection cases in recent years in Hebei Province, China, and transmission via blood is one of the risk factors in the early. This article aimed to investigate the HIV ...

    Authors: Suliang Chen, Hongru Zhao, Cuiying Zhao, Yuqi Zhang, Baojun Li, Guangyi Bai, Liang Liang and Xinli Lu
    Citation: BMC Infectious Diseases 2015 15:316
    Content type: Research article Published on:

  45. Regular clinical care is important for the well-being of people with HIV. We sought to  audit and describe the characteristics of adults with diagnosed HIV infection not reported to be attending for clinical c...

    Authors: Hilary Curtis, Z. Yin, K. Clay, A. E. Brown, V. C. Delpech and E. Ong
    Citation: BMC Infectious Diseases 2015 15:315
    Content type: Research article Published on:

  46. Ventilator-associated pneumonia (VAP) is a serious health care- associated infection, resulting in high morbidity and mortality. It also prolongs hospital stay and drives up hospital costs. Measures employed i...

    Authors: Seham F. A. Azab, Hanan S. Sherbiny, Safaa H. Saleh, Wafaa F. Elsaeed, Mona M. Elshafiey, Ahmed G. Siam, Mohamed A. Arafa, Ashgan A. Alghobashy, Eman A. Bendary, Maha A. A. Basset, Sanaa M. Ismail, Nagwa E. Akeel, Nahla A. Elsamad, Wesam A. mokhtar and Tarek Gheith
    Citation: BMC Infectious Diseases 2015 15:314
    Content type: Research article Published on:

  47. Empiric therapy for healthcare-associated infections remains challenging, especially with the continued development of Gram-negative organisms producing extended-spectrum β-lactamases (ESBLs) and the threat of...

    Authors: Yoav Golan
    Citation: BMC Infectious Diseases 2015 15:313
    Content type: Research article Published on:

  48. The risk factors, microbial etiology, differentiation, and clinical features of purulent and non-purulent cellulitis are not well defined in Taiwan.

    Authors: Chun-Yuan Lee, Hung-Chin Tsai, Calvin M. Kunin, Susan Shin-Jung Lee and Yao-Shen Chen
    Citation: BMC Infectious Diseases 2015 15:311
    Content type: Research article Published on:

  49. Several human diseases are caused by Streptococcus pyogenes, ranging from common infections to autoimmunity. Characterization of the most prevalent strains worldwide is a useful tool for evaluating the coverage c...

    Authors: Samar Freschi de Barros, Karine Marafigo De Amicis, Raquel Alencar, Pierre Robert Smeesters, Ariel Trunkel, Edilberto Postól, João Nóbrega Almeida Junior, Flavia Rossi, Antonio Carlos Campos Pignatari, Jorge Kalil and Luiza Guilherme
    Citation: BMC Infectious Diseases 2015 15:308
    Content type: Research article Published on:

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