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  1. While the macrophage polarization is well characterized in helminth infections, the natural heterogeneity of monocytes with multiple cell phenotypes might influence the outcome of neglected diseases, such hook...

    Authors: Lívia Silva Araújo Passos, Pedro Henrique Gazzinelli-Guimarães, Tiago Antônio de Oliveira Mendes, Ana Clara Gazzinelli Guimarães, Denise da Silveira Lemos, Natasha Delaqua Ricci, Ricardo Gonçalves, Daniella Castanheira Bartholomeu, Ricardo Toshio Fujiwara and Lilian Lacerda Bueno
    Citation: BMC Infectious Diseases 2017 17:253
  2. Death under care is a major challenge for tuberculosis (TB) treatment programs. We derived and validated a simple score to predict mortality during tuberculosis treatment in high endemicity areas.

    Authors: Eric Walter Pefura-Yone, Adamou Dodo Balkissou, Virginie Poka-Mayap, Hadja Koté Fatime-Abaicho, Patrick Thierry Enono-Edende and André Pascal Kengne
    Citation: BMC Infectious Diseases 2017 17:251
  3. Rubella is an acute infectious disease caused by Rubella virus (RUBV). RUBV remains an important pathogen worldwide, causing approximately 100 000 cases of congenital rubella syndrome (CRS) every year; and the...

    Authors: Josue Zanga, Makola Kennedy Mbanzulu, Arnold-Freddy Kabasele, Nlandu Roger Ngatu and Dimosi Roger Wumba
    Citation: BMC Infectious Diseases 2017 17:250
  4. Human papillomavirus (HPV) is one of the most common sexually transmitted pathogens. This observational study was conducted to estimate the trend of hospitalization for genital warts (GWs) in the Veneto region...

    Authors: Silvia Cocchio, Tatjana Baldovin, Chiara Bertoncello, Alessandra Buja, Patrizia Furlan, Mario Saia and Vincenzo Baldo
    Citation: BMC Infectious Diseases 2017 17:249
  5. Beta-hemolytic streptococci carrier rates in children living in low-income countries are high ranging from 10 to 50%. Although most of these children are asymptomatic, they are a reservoir and pose a risk of t...

    Authors: Irene Nayiga, Emmy Okello, Peter Lwabi and Grace Ndeezi
    Citation: BMC Infectious Diseases 2017 17:248
  6. Tetanus-reduced dose diphtheria-acellular pertussis (Tdap) vaccination during adolescence was introduced in response to the resurgence of pertussis in various countries. A new Tdap vaccine was manufactured in ...

    Authors: Hyo Jin Kwon, Seung Beom Han, Bo Ram Kim, Kyu Ri Kang, Dong Ho Huh, Gi Sub Choi, Dong Ho Ahn and Jin Han Kang
    Citation: BMC Infectious Diseases 2017 17:247
  7. Combination antiretroviral therapy (cART) has reduced mortality from AIDS-related illnesses and chronic comorbidities have become prevalent among HIV-infected patients. We examined the association between hepa...

    Authors: Carmine Rossi, Janet Raboud, Sharon Walmsley, Curtis Cooper, Tony Antoniou, Ann N. Burchell, Mark Hull, Jason Chia, Robert S. Hogg, Erica E.M. Moodie and Marina B. Klein
    Citation: BMC Infectious Diseases 2017 17:246
  8. Respiratory morbidity in Australian Indigenous children is higher than their non-Indigenous counterparts, irrespective of urban or remote residence. There are limited studies addressing acute respiratory illne...

    Authors: Kerry-Ann F. O’Grady, Kerry K. Hall, Theo P. Sloots, Jennie Anderson and Anne B. Chang
    Citation: BMC Infectious Diseases 2017 17:245
  9. Schistosomiasis, one of the neglected tropical diseases, is endemic in more than 70 countries. However, the clinical diagnosis of patients with a low degree of infection is an unsolved...

    Authors: Kongzhen Gu, Yuesheng Li, Patrick Driguez, Qingren Zeng, Xinlin Yu, Hui Sun, Liting Cai, Yongkang He, Wenyang Wang and Donald P. McManus
    Citation: BMC Infectious Diseases 2017 17:244
  10. Outbreaks of measles re-emerged in Guangxi province during 2013–2014, where measles again became a major public health concern. A better understanding of the patterns of measles cases would help in identifying...

    Authors: Xianyan Tang, Alan Geater, Edward McNeil, Qiuyun Deng, Aihu Dong and Ge Zhong
    Citation: BMC Infectious Diseases 2017 17:243
  11. Pertussis (whooping cough) is well known to be underreported, particularly among adults, who can act as an infectious reservoir, potentially putting susceptible newborns at risk of serious illness. The purpose...

    Authors: Péter Torzsa, Raghavendra Devadiga and Monica Tafalla
    Citation: BMC Infectious Diseases 2017 17:242
  12. Current influenza vaccines, based on antibodies against surface antigens, are unable to provide protection against newly emerging virus strains which differ from the vaccine strains. Therefore the population h...

    Authors: Eva van Doorn, Olga Pleguezuelos, Heng Liu, Ana Fernandez, Robin Bannister, Gregory Stoloff, Fredrik Oftung, Stephen Norley, Anke Huckriede, Henderik W. Frijlink and Eelko Hak
    Citation: BMC Infectious Diseases 2017 17:241
  13. Acute focal bacterial nephritis (AFBN) is a rare disease currently described only in case reports and small case series. In this study we summarize the clinical features of AFBN as has been documented in the l...

    Authors: Nadine Sieger, Iason Kyriazis, Alexander Schaudinn, Panagiotis Kallidonis, Jochen Neuhaus, Evangelos N. Liatsikos, Roman Ganzer and Jens-Uwe Stolzenburg
    Citation: BMC Infectious Diseases 2017 17:240
  14. Two lineages of Zika virus (ZIKV) have been classified according to the phylogenetic analysis: African and Asian lineages. It is unclear whether differences exist between the two strains in host cell permissiv...

    Authors: Wangheng Hou, Najealicka Armstrong, Lilian Akello Obwolo, Michael Thomas, Xiaowu Pang, Kevin S. Jones and Qiyi Tang
    Citation: BMC Infectious Diseases 2017 17:239
  15. Seasonal influenza epidemics place considerable strain on health services. Robust systems of surveillance are therefore required to ensure preparedness. Sentinel surveillance does not accurately capture the co...

    Authors: Maria Peppa, W. John Edmunds and Sebastian Funk
    Citation: BMC Infectious Diseases 2017 17:238
  16. Children with cardiac defects need many hospitalizations and repetitive antibiotic therapies, with an increasing risk of colonization with multidrug-resistant bacteria (MDRB) such as extended-spectrum β-lactam...

    Authors: Amine Cheikh, Bouchra Belefquih, Younes Chajai, Younes Cheikhaoui, Amine El Hassani and Amina Benouda
    Citation: BMC Infectious Diseases 2017 17:237
  17. Tuberculosis and HIV co-infection is one of the main drivers of poor outcome for both diseases in Zambia. HIV infection has been found to predict TB infection/disease and TB has been reported as a major cause ...

    Authors: Pascalina Chanda-Kapata, Nathan Kapata, Eveline Klinkenberg, Martin P. Grobusch and Frank Cobelens
    Citation: BMC Infectious Diseases 2017 17:236
  18. In chronic hepatitis C, the fibrosis progression rates are extremely variable and can be influenced by factors associated with the host, virus and environment. Among the associated metabolic factors, hepatic s...

    Authors: Mariana Cavalheiro Magri, Thamiris Vaz Gago Prata, Caroline Manchiero, Bianca Peixoto Dantas, Celso Carmo Mazza and Fátima Mitiko Tengan
    Citation: BMC Infectious Diseases 2017 17:235
  19. Increased incidence of cardiovascular diseases (CVD) in both HIV infection and type 2 diabetes (T2D) compared to the general population has been described. Little is known about the combined effect of HIV infe...

    Authors: Malene Hove-Skovsgaard, Julie Christine Gaardbo, Lilian Kolte, Kamilla Winding, Ingebjørg Seljeflot, Asbjørn Svardal, Rolf Kristian Berge, Jan Gerstoft, Henrik Ullum, Marius Trøseid and Susanne Dam Nielsen
    Citation: BMC Infectious Diseases 2017 17:234
  20. Culturing has long been the gold standard for detecting aetiologic agents in bacterial infections. In some cases, however, culturing fails to detect the infection. To further investigate culture-negative sampl...

    Authors: Camilla Stavnsbjerg, Niels Frimodt-Møller, Claus Moser and Thomas Bjarnsholt
    Citation: BMC Infectious Diseases 2017 17:233
  21. Vaccination against seasonal influenza strains is recommended for “high risk” patient groups such as infants, elderly and those with respiratory or circulatory diseases. However, efficacy of the trivalent infl...

    Authors: M. D Heath, N. J. Swan, A. C. Marriott, N. J. Silman, B. Hallis, C. Prevosto, K. E. Gooch and M. A. Skinner
    Citation: BMC Infectious Diseases 2017 17:232
  22. We describe drug-induced liver injury (DILI) secondary to antituberculous treatment (ATT) in a large tuberculosis (TB) centre in London; we identify the proportion who had risk factors for DILI and the timing ...

    Authors: Aula Abbara, Sarah Chitty, Jennifer K. Roe, Rohma Ghani, Simon M. Collin, Andrew Ritchie, Onn Min Kon, John Dzvova, Harriet Davidson, Thomas E. Edwards, Charlotte Hateley, Matthew Routledge, Jim Buckley, Robert N. Davidson and Laurence John
    Citation: BMC Infectious Diseases 2017 17:231
  23. Identification of carbapenemase-producing Enterobacteriaceae (CPE) in faecal specimens is challenging. This fact is particularly critical because low-level carbapenem-resistant organisms such as IMP-producing CPE...

    Authors: Norihisa Yamamoto, Ryuji Kawahara, Yukihiro Akeda, Rathina Kumar Shanmugakani, Hisao Yoshida, Hideharu Hagiya, Naohiro Hara, Isao Nishi, Satomi Yukawa, Rumiko Asada, Yumi Sasaki, Kazuhiro Maeda, Noriko Sakamoto, Shigeyuki Hamada and Kazunori Tomono
    Citation: BMC Infectious Diseases 2017 17:229
  24. Levels of non-neutralising antibodies (AB) to the C5 domain of HIV Env gp120 are inversely related to progression of HIV infection. In this phase I/II clinical study we investigated safety of Vacc-C5, a peptid...

    Authors: Kristin Brekke, Maja Sommerfelt, Mats Ökvist, Anne Margarita Dyrhol-Riise and Dag Kvale
    Citation: BMC Infectious Diseases 2017 17:228
  25. Periprosthetic joint infections are mainly caused by Gram-positive cocci. Leuconostoc mesenteroides is a rare microorganism mainly causing bloodstream infections. At times, it might be confused with another type ...

    Authors: Rafael Franco-Cendejas, Claudia A. Colín-Castro, Melissa Hernández-Durán, Luis E. López-Jácome, Silvestre Ortega-Peña, Guillermo Cerón-González, Samuel Vanegas-Rodríguez, Jaime A. Mondragón-Eguiluz and Eduardo Acosta-Rodríguez
    Citation: BMC Infectious Diseases 2017 17:227
  26. There is limited data on the genotype distribution of human papillomavirus (HPV) in the Taihu River Basin, home to 1.29 million people on the coast of eastern China. This study evaluated the prevalence and gen...

    Authors: Jing-fen Lu, Guo-rong Shen, Qiong Li, Xu Chen, Chun-fang Ma and Tong-hua Zhu
    Citation: BMC Infectious Diseases 2017 17:226
  27. Cryptococcal meningitis (CM) constitutes a significant source of mortality in resource-limited regions. Cryptococcal antigen (CRAG) can be detected in the blood before onset of meningitis. We sought to determi...

    Authors: Anu Ramachandran, Yukari Manabe, Radha Rajasingham and Maunank Shah
    Citation: BMC Infectious Diseases 2017 17:225
  28. The outcome of CMV/HIV co-infection in infants treated early with combined antiretroviral therapy (cART) in resource-limited settings has not been described.

    Authors: Anfumbom K. W. Kfutwah, Paul Alain T. Ngoupo, Casimir Ledoux Sofeu, Francis Ateba Ndongo, Georgette Guemkam, Suzie Tetang Ndiang, Félicité Owona, Ida Calixte Penda, Patrice Tchendjou, Christine Rouzioux, Josiane Warszawski, Albert Faye and Mathurin Cyrille Tejiokem
    Citation: BMC Infectious Diseases 2017 17:224
  29. Leishmaniasis is a spectrum of diseases with great relevance to public health. Conventional diagnostic methods are time consuming, needing trained personnel. A robust, rapid and cost effective diagnostic test ...

    Authors: Sandeep Verma, Ruchi Singh, Vanila Sharma, Ram Avtar Bumb, Narendra Singh Negi, V Ramesh and Poonam Salotra
    Citation: BMC Infectious Diseases 2017 17:223
  30. This multi-country prospective study of infants aged <1 year aims to assess the frequency of influenza virus and respiratory syncytial virus (RSV) infections associated with hospitalizations, to describe clini...

    Authors: Mark G. Thompson, Danielle R. Hunt, Ali K. Arbaji, Artan Simaku, Veronica L. Tallo, Holly M. Biggs, Carolyn Kulb, Aubree Gordon, Ilham Abu Khader, Silvia Bino, Marilla G. Lucero, Eduardo Azziz-Baumgartner, Pat Shifflett, Felix Sanchez, Basima I. Marar, Ilirjana Bakalli…
    Citation: BMC Infectious Diseases 2017 17:222
  31. Chagas disease is caused by the protozoan Trypanosoma cruzi and is characterized by heart failure and sudden death. Identifying which factors are involved in evolution and treatment response is actually challengi...

    Authors: Héctor Rodríguez-Angulo, Juan Marques, Ivan Mendoza, Marco Villegas, Alfredo Mijares, Núria Gironès and Manuel Fresno
    Citation: BMC Infectious Diseases 2017 17:221
  32. Cytomegalovirus (CMV), Epstein Barr virus (EBV) and varicella-zoster virus (VZV) are common herpesviruses frequently acquired in childhood, which establish persistent, latent infection and are likely to impact...

    Authors: Lucy Pembrey, Dagmar Waiblinger, Paul Griffiths, Mauli Patel, Rafaq Azad and John Wright
    Citation: BMC Infectious Diseases 2017 17:220
  33. Efforts to control the global burden of tuberculosis (TB) have been jeopardized by the rapid evolution of multi-drug resistant Mycobacterium tuberculosis (MTB), which is resistant to at least isoniazid and rifamp...

    Authors: Setegn Eshetie, Mucheye Gizachew, Mulat Dagnew, Gemechu Kumera, Haile Woldie, Fekadu Ambaw, Belay Tessema and Feleke Moges
    Citation: BMC Infectious Diseases 2017 17:219
  34. In Vietnam, dengue fever (DF) is still a leading cause of hospitalization. The main objective of this study was to evaluate the seasonality and association with climate factors (temperature and precipitation) ...

    Authors: Hu Suk Lee, Hung Nguyen-Viet, Vu Sinh Nam, Mihye Lee, Sungho Won, Phuc Pham Duc and Delia Grace
    Citation: BMC Infectious Diseases 2017 17:218
  35. Herpes simplex virus (HSV) is a common human pathogen that causes a variety of diseases, including oral-labial, genital lesions and life-threatening encephalitis. The antiviral nucleoside analogues such as acy...

    Authors: Jue Hou, Zili Zhang, Qiang Huang, Jun Yan, Xiaohu Zhang, Xiaoliang Yu, Guihua Tan, Chunfu Zheng, Feng Xu and Sudan He
    Citation: BMC Infectious Diseases 2017 17:217
  36. Imported cases of infections due to Dengue (DENV) and Chikungunya (CHIKV) viruses and, more recently, Zika virus (ZIKV) are commonly reported among travelers returning from endemic regions. In areas where pote...

    Authors: Claudia Fortuna, Maria Elena Remoli, Caterina Rizzo, Eleonora Benedetti, Cristiano Fiorentini, Antonino Bella, Claudio Argentini, Francesca Farchi, Concetta Castilletti, Maria Rosaria Capobianchi, Lorenzo Zammarchi, Alessandro Bartoloni, Nadia Zanchetta, Maria Rita Gismondo, Luca Ceccherini Nelli, Giustina Vitale…
    Citation: BMC Infectious Diseases 2017 17:216

    The Erratum to this article has been published in BMC Infectious Diseases 2017 17:335

  37. Little is known about the applicability of dual treatments based on integrase inhibitors. We explored the combination of lamivudine + dolutegravir as an option when switching from standard cART in virologicall...

    Authors: Franco Maggiolo, Roberto Gulminetti, Layla Pagnucco, Margherita Digaetano, Simone Benatti, Daniela Valenti, Annapaola Callegaro, Diego Ripamonti and Cristina Mussini
    Citation: BMC Infectious Diseases 2017 17:215
  38. The real burden of smear-positive (PTB+) and bacteriologically confirmed tuberculosis (BCTB) in Ethiopia is not known. Thus, the aim of this community-based study was to measure the prevalence and incidence of...

    Authors: ShalloDaba Hamusse, Meaza Demissie, Dejene Teshome, Mohammed Suaudi Hassen and Bernt Lindtjørn
    Citation: BMC Infectious Diseases 2017 17:214
  39. Herpes zoster (HZ) is a prevalent viral disease that inflicts substantial morbidity and associated healthcare and socioeconomic burdens. Current treatments are not fully effective, especially among the most vu...

    Authors: Liang-Kung Chen, Hidenori Arai, Liang-Yu Chen, Ming-Yueh Chou, Samsuridjal Djauzi, Birong Dong, Taro Kojima, Ki Tae Kwon, Hoe Nam Leong, Edward M. F. Leung, Chih-Kuang Liang, Xiaohong Liu, Dilip Mathai, Jiun Yit Pan, Li-Ning Peng, Eduardo Rommel S. Poblete…
    Citation: BMC Infectious Diseases 2017 17:213
  40. Atazanavir (ATV) not boosted by ritonavir (uATV) has been frequently used in the past for switching combination antiretroviral therapy (cART). However, the clinical outcomes and predictors of such strategy are...

    Authors: Maria Concetta Postorino, Mattia Prosperi, Emanuele Focà, Eugenia Quiros-Roldan, Elisa Di Filippo, Franco Maggiolo, Alberto Borghetti, Nicoletta Ladisa, Massimo Di Pietro, Andrea Gori, Laura Sighinolfi, Angelo Pan, Nicola Mazzini and Carlo Torti
    Citation: BMC Infectious Diseases 2017 17:212
  41. Although sickle cell disease (SCD) children are highly susceptible to bacterial infections (BIs), there is a dreadful lack of data related to the burden and spectrum of BIs in sub-Saharan Africa (SSA), the hig...

    Authors: Anastasie Nicole Alima Yanda, Jobert Richie N. Nansseu, Hubert Désiré Mbassi Awa, Sandra A. Tatah, Judith Seungue, Charlotte Eposse and Paul Olivier N. Koki
    Citation: BMC Infectious Diseases 2017 17:211
  42. Mannose-binding lectin (MBL) is an important protein in the lectin pathway of the immune system. This study explores the association between MBL polymorphism and the susceptibility to tuberculosis (TB). The as...

    Authors: Yan-Ling Guo, Yang Liu, Wu-Juan Ban, Qi Sun and Guang-Li Shi
    Citation: BMC Infectious Diseases 2017 17:210
  43. Three diagnostic criteria have been proposed used for invasive pulmonary aspergillosis (IPA) diagnosis, namely EORTC/ MSG criteria, Bulpa criteria and intensive care unit (ICU) criteria. The Bulpa criteria wer...

    Authors: Linna Huang, Hangyong He, Jingjing Jin and Qingyuan Zhan
    Citation: BMC Infectious Diseases 2017 17:209
  44. The sustained health-related quality-of-life of patients surviving community-acquired pneumonia has not been accurately quantified. The aim of the current study was to quantify differences in health-related qu...

    Authors: Marie-Josée J. Mangen, Susanne M. Huijts, Marc J. M. Bonten and G. Ardine de Wit
    Citation: BMC Infectious Diseases 2017 17:208
  45. External and intraocular infections can lead to visual impairments, which is a major public health problem. Bacteria are the most frequent pathogens affecting ocular structures; the increasing rate of antimicr...

    Authors: Mebrahtu Teweldemedhin, Muthupandian Saravanan, Araya Gebreyesus and Dawit Gebreegziabiher
    Citation: BMC Infectious Diseases 2017 17:207
  46. Routes of transmission of multidrug-resistant gram-negative organisms (MDRGN) are not completely understood. Since sexual transmission of MDRGN might represent a potential mode that has not been noticed so far...

    Authors: Claudia Reinheimer, Oliver T. Keppler, Christoph Stephan, Thomas A. Wichelhaus, Imke Friedrichs and Volkhard A. J. Kempf
    Citation: BMC Infectious Diseases 2017 17:206
  47. Studies from several countries indicate that the incidence and mortality of bloodstream infection (BSI) have been increasing over time.

    Authors: Arne Mehl, Bjørn Olav Åsvold, Stian Lydersen, Julie Paulsen, Erik Solligård, Jan Kristian Damås, Stig Harthug and Tom-Harald Edna
    Citation: BMC Infectious Diseases 2017 17:205
  48. Dengue is an acute febrile illness considered the major arboviral disease in terms of morbidity, mortality, economic impact and dissemination worldwide. Brazil accounts for the highest notification rate, with ...

    Authors: Sibelle Nogueira Buonora, Flavia Barreto dos Santos, Regina Paiva Daumas, Sonia Regina Lambert Passos, Manoela Heringer da Silva, Monique Rocha de Lima and Rita Maria Ribeiro Nogueira
    Citation: BMC Infectious Diseases 2017 17:204
  49. Carbapenem-resistant Klebsiella pneumoniae (CRKP) spread and infections in patients with haematological malignancies are a serious concern especially in endemic areas. Treatment failures and delay in appropriate ...

    Authors: Alessandra Micozzi, Giuseppe Gentile, Clara Minotti, Claudio Cartoni, Saveria Capria, Daniele Ballarò, Stefania Santilli, Emanuele Pacetti, Sara Grammatico, Giampaolo Bucaneve and Robin Foà
    Citation: BMC Infectious Diseases 2017 17:203

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