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  1. Schistosomiasis is a major parasitic disease affecting over 200 million people in the developing world with a further 400 million people at risk of infection. The aim of this study was to identify a single ant...

    Authors: Francisca Mutapi, Takafira Mduluza, Natalia Gomez-Escobar, William F Gregory, Cecilia Fernandez, Nicholas Midzi and Rick M Maizels

    Citation: BMC Infectious Diseases 2006 6:96

    Content type: Research article

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  2. We have previously shown the high prevalence of oral anti-human papillomavirus type 16 (HPV-16) antibodies in women with HPV-associated cervical neoplasia. It was postulated that the HPV antibodies were initia...

    Authors: Dianne J Marais, Candice Sampson, Anthea Jeftha, Dherendra Dhaya, Jo-Ann S Passmore, Lynette Denny, Edward P Rybicki, Eric Van Der Walt, Lawrence XG Stephen and Anna-Lise Williamson

    Citation: BMC Infectious Diseases 2006 6:95

    Content type: Research article

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  3. Patients prescribed intravenous (IV) glycopeptides usually remain in hospital until completion of this treatment. Some of these patients could be discharged earlier if a switch to an oral antibiotic was made. ...

    Authors: Mohammed Desai, Bryony Dean Franklin, Alison H Holmes, Sarah Trust, Mike Richards, Ann Jacklin and Kathleen B Bamford

    Citation: BMC Infectious Diseases 2006 6:94

    Content type: Research article

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  4. Injecting drug use is a key risk factor, for several infections of public health importance, especially hepatitis B (HBV) and hepatitis C (HCV). In England and Wales, where less than 1% of the population are l...

    Authors: AJ Sutton, NJ Gay, WJ Edmunds, VD Hope, ON Gill and M Hickman

    Citation: BMC Infectious Diseases 2006 6:93

    Content type: Research article

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  5. Infectious diseases are often studied by characterising the population structure of the pathogen using genetic markers. An unresolved problem is the effective quantification of the extent of transmission using...

    Authors: Mark M Tanaka, Renault Phong and Andrew R Francis

    Citation: BMC Infectious Diseases 2006 6:92

    Content type: Research article

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  6. This study was conducted to examine, in vitro , the effect of soluble egg antigen (SEA) of S. haematobium on intracellular HCV RNA load in peripheral mononuclear cells (PBMC) as well as on cell proliferation in p...

    Authors: Mostafa K El-Awady, Samar S Youssef, Moataza H Omran, Ashraf A Tabll, Wael T El Garf and Ahmed M Salem

    Citation: BMC Infectious Diseases 2006 6:91

    Content type: Research article

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  7. Microbicides must protect against STD pathogens without causing unacceptable toxic effects. Microbicides based on nonoxynol-9 (N9) and other detergents disrupt sperm, HSV and HIV membranes, and these agents ar...

    Authors: Richard A Cone, Timothy Hoen, XiXi Wong, Raed Abusuwwa, Deborah J Anderson and Thomas R Moench

    Citation: BMC Infectious Diseases 2006 6:90

    Content type: Research article

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  8. As a greater number of HIV-infected patients survive despite profound immunodepression due to medical progress, we face complex infection with multiple agents in AIDS-patients.

    Authors: Clarisse Rovery, Jean Marc Rolain, Hubert Lepidi, Christine Zandotti, Jacques Moreau and Philippe Brouqui

    Citation: BMC Infectious Diseases 2006 6:89

    Content type: Case report

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  9. Ascariasis and HIV/AIDS are often co-endemic under conditions of poverty in South Africa; and discordant immune responses to the respective infections could theoretically be affecting the epidemic of HIV/AIDS ...

    Authors: Vera J Adams, Miles B Markus, Zilungile L Kwitshana, Muhammad A Dhansay, Lize van der Merwe, Gerhard Walzl and John E Fincham

    Citation: BMC Infectious Diseases 2006 6:88

    Content type: Research article

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  10. Avian influenza viruses (AIVs) are endemic in wild birds and their introduction and conversion to highly pathogenic avian influenza virus in domestic poultry is a cause of serious economic losses as well as a ...

    Authors: Livia Di Trani, Barbara Bedini, Isabella Donatelli, Laura Campitelli, Barbara Chiappini, Maria Alessandra De Marco, Mauro Delogu, Canio Buonavoglia and Gabriele Vaccari

    Citation: BMC Infectious Diseases 2006 6:87

    Content type: Research article

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  11. Helicobacter cinaedi is a rare pathogen in humans, occurring mostly in immuno-compromised patients, with a high potential for recurrence. We describe a case of a patient with lymphoma hospitalized for chemothera...

    Authors: Ilker Uçkay, Jorge Garbino, Pierre-Yves Dietrich, Béatrice Ninet, Peter Rohner and Véronique Jacomo

    Citation: BMC Infectious Diseases 2006 6:86

    Content type: Case report

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  12. Low serum selenium has been associated with lower CD4 counts and greater mortality among HIV-1-seropositive individuals, but most studies have not controlled for serum albumin and the presence of an acute phas...

    Authors: Paul K Drain, Jared M Baeten, Julie Overbaugh, Mark H Wener, Daniel D Bankson, Ludo Lavreys, Kishorchandra Mandaliya, Jeckoniah O Ndinya-Achola and R Scott McClelland

    Citation: BMC Infectious Diseases 2006 6:85

    Content type: Research article

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  13. Cytokines play important roles in antiviral action. We examined whether polymorphisms of IFN-γ,TNF-α and IL-10 affect the susceptibility to and outcome of severe acute respiratory syndrome (SARS).

    Authors: Wai Po Chong, WK Eddie Ip, Gloria Hoi Wan Tso, Man Wai Ng, Wilfred Hing Sang Wong, Helen Ka Wai Law, Raymond WH Yung, Eudora Y Chow, KL Au, Eric YT Chan, Wilina Lim, JS Malik Peiris and Yu Lung Lau

    Citation: BMC Infectious Diseases 2006 6:82

    Content type: Research article

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  14. Evidence for an increased prevalence of candidaemia and for high associated mortality in the 1990s led to a number of different recommendations concerning the management of at risk patients as well as an incre...

    Authors: Boualem Sendid, Angélique Cotteau, Nadine François, Annie D'Haveloose, Annie Standaert, Daniel Camus and Daniel Poulain

    Citation: BMC Infectious Diseases 2006 6:80

    Content type: Research article

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  15. previous studies have established that bacterial blood concentration is related with clinical outcome. Time to positivity of blood cultures (TTP) has relationship with bacterial blood concentration and could be ...

    Authors: Galo Peralta, María José Rodríguez-Lera, Jose Carlos Garrido, Luis Ansorena and María Pía Roiz

    Citation: BMC Infectious Diseases 2006 6:79

    Content type: Research article

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  16. Despite bacteraemia is present in the majority of patients with pneumococcal, little is known about the influence of the systemic infection on the meningeal inflammatory response.

    Authors: Christian ∅stergaard, Terence O'Reilly, Christian Brandt, Niels Frimodt-Møller and Jens D Lundgren

    Citation: BMC Infectious Diseases 2006 6:78

    Content type: Research article

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  17. Hemorrhagic fever with renal syndrome (HFRS) is endemic in many provinces with high incidence in mainland China, although integrated intervention measures including rodent control, environment management and v...

    Authors: Liqun Fang, Lei Yan, Song Liang, Sake J de Vlas, Dan Feng, Xiaona Han, Wenjuan Zhao, Bing Xu, Ling Bian, Hong Yang, Peng Gong, Jan Hendrik Richardus and Wuchun Cao

    Citation: BMC Infectious Diseases 2006 6:77

    Content type: Research article

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  18. Post-sternotomy mediastinitis (PSM) is a devastating surgical complication affecting 1–3% of patients that undergo cardiac surgery. Staphylococcus aureus is one of the most commonly encountered bacterial pathogen...

    Authors: Gulden Ersoz, Barlas Naim Aytacoglu, Nehir Sucu, Lulufer Tamer, Ismet Bayindir, Necmi Kose, Ali Kaya and Murat Dikmengil

    Citation: BMC Infectious Diseases 2006 6:76

    Content type: Research article

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  19. Disseminated leishmaniasis is an emerging infectious disease, mostly due to L. braziliensis, which has clinical and histopathological features distinct from cutaneous leishmaniasis.

    Authors: Paulo TG Leopoldo, Paulo RL Machado, Roque P Almeida, Albert Schriefer, Angela Giudice, Amélia Ribeiro de Jesus, John L Ho, Luiz Henrique Guimarães, Olívia Bacellar and Edgar M Carvalho

    Citation: BMC Infectious Diseases 2006 6:75

    Content type: Research article

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  20. Daptomycin is a novel cyclic lipopeptide whose bactericidal activity is not affected by current antibiotic resistance mechanisms displayed by S. aureus clinical isolates. This study reports the therapeutic activi...

    Authors: Heinz J Schaad, Manuela Bento, Daniel P Lew and Pierre Vaudaux

    Citation: BMC Infectious Diseases 2006 6:74

    Content type: Research article

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  21. Fungal mural endocarditis is a rare entity in which the antemortem diagnosis is seldom made. Seven cases of mural endocarditis caused by Candida spp. have been collected from literature and six of these patients ...

    Authors: Víctor López-Ciudad, María J Castro-Orjales, Cristóbal León, César Sanz-Rodríguez, María J de la Torre-Fernández, Miguel A Pérez de Juan-Romero, María D Collell-Llach and María D Díaz-López

    Citation: BMC Infectious Diseases 2006 6:73

    Content type: Case report

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  22. The optimal treatment regimen and duration of the therapy is still controversial in spinal brucellosis. The aim of this study is to compare the efficacy, adverse drug reactions, complications and cost of cipro...

    Authors: Emine Alp, Rahmi Kemal Koc, Ahmet Candan Durak, Orhan Yildiz, Bilgehan Aygen, Bulent Sumerkan and Mehmet Doganay

    Citation: BMC Infectious Diseases 2006 6:72

    Content type: Research article

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  23. Adherence of Streptococcus pneumoniae bacteria to lung cells is a first step in the progression from asymptomatic carriage to pneumonia. Adherence abilities vary widely among S. pneumoniae patient isolates. In th...

    Authors: Rachel L Robson, Natalie A Reed and Rebecca T Horvat

    Citation: BMC Infectious Diseases 2006 6:71

    Content type: Research article

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  24. The seasonality, clinical and radiographic features and outcome of aseptic meningitis have been described for regional outbreaks but data from a wider geographic area is necessary to delineate the epidemiology...

    Authors: Bonita E Lee, Rupesh Chawla, Joanne M Langley, Sarah E Forgie, Mohammed Al-Hosni, Krista Baerg, Entesar Husain, James Strong, Joan L Robinson, Upton Allen, Barbara J Law, Simon Dobson and H Dele Davies

    Citation: BMC Infectious Diseases 2006 6:68

    Content type: Research article

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  25. Recent data demonstrate the utility of the string test for the diagnosis of sputum-scarce HIV-associated TB in adults. We hypothesized that, if well-tolerated by children, this simple tool might offer a breakt...

    Authors: Felicia Chow, Nora Espiritu, Robert H Gilman, Rosmery Gutierrez, Sonia Lopez, A Roderick Escombe, Carlton AW Evans and David AJ Moore

    Citation: BMC Infectious Diseases 2006 6:67

    Content type: Research article

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  26. New tools are required to improve tuberculosis (TB) diagnosis and treatment, including enhanced ability to compare new treatment strategies. The ELISPOT assay uses Mycobacterium tuberculosis-specific antigens to ...

    Authors: Alexander M Aiken, Philip C Hill, Annette Fox, Keith PWJ McAdam, Dolly Jackson-Sillah, Moses D Lugos, Simon A Donkor, Richard A Adegbola and Roger H Brookes

    Citation: BMC Infectious Diseases 2006 6:66

    Content type: Research article

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  27. Patients with HIV infection are at risk of co-infection with HBV, as the routes of transmission are shared and thus immunization with HBV vaccine could be protective in them. The aim of the present study was t...

    Authors: Neelam Pasricha, Usha Datta, Yogesh Chawla, Surjit Singh, Sunil K Arora, Archana Sud, Ranjana W Minz, Biman Saikia, Haqeeqat Singh, Isaac James and Shobha Sehgal

    Citation: BMC Infectious Diseases 2006 6:65

    Content type: Research article

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  28. The way various antiretroviral drugs and drug combinations affect HIV-1 infection in the central nervous system is still largely unknown. The aim of this study was to determine the cerebrospinal fluid (CSF) st...

    Authors: Aylin Yilmaz, Dietmar Fuchs, Lars Hagberg, Ulrika Nillroth, Lars Ståhle, Jan-Olof Svensson and Magnus Gisslén

    Citation: BMC Infectious Diseases 2006 6:63

    Content type: Research article

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  29. Streptococcus intermedius belongs to the Streptococcus anginosus group. It is part of the normal flora of the human mouth, but it can be etiologically associated with deep-site infections.

    Authors: Donato Rigante, Teresa Spanu, Lorenzo Nanni, Assunta Tornesello, Maurizio Sanguinetti, Tiziana D'Inzeo, Achille Stabile and Giovanni Fadda

    Citation: BMC Infectious Diseases 2006 6:61

    Content type: Technical advance

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  30. Mediterranean spotted fever (MSF) is an acute febrile, zoonotic disease caused by Rickettsia conorii and transmitted to humans by the brown dogtick Rhipicephalus sanguineus. Nearly four hundred cases are reported...

    Authors: Claudia Colomba, Laura Saporito, Valentina Frasca Polara, Raffaella Rubino and Lucina Titone

    Citation: BMC Infectious Diseases 2006 6:60

    Content type: Research article

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  31. Patients accessing antiretroviral treatment (ART) programmes in sub-Saharan Africa frequently have very advanced immunodeficiency. Previous data suggest that such patients may have diminished capacity for CD4 ...

    Authors: Stephen D Lawn, Landon Myer, Linda-Gail Bekker and Robin Wood

    Citation: BMC Infectious Diseases 2006 6:59

    Content type: Research article

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  32. Influenza is characterized by seasonal outbreaks, often with a high rate of morbidity and mortality. It is also known to be a cause of significant amount secondary bacterial infections. Streptococcus pneumoniae i...

    Authors: Katarzyna Grabowska, Liselotte Högberg, Pasi Penttinen, Åke Svensson and Karl Ekdahl

    Citation: BMC Infectious Diseases 2006 6:58

    Content type: Research article

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  33. Group B Streptococcus (GBS) remains susceptible to penicillin, however, resistance to second-line antimicrobials, clindamycin and erythromycin, has increased since 1996. We describe the age-specific antibiotic su...

    Authors: Stephanie M Borchardt, Joan H DeBusscher, Patricia A Tallman, Shannon D Manning, Carl F Marrs, Terrence A Kurzynski and Betsy Foxman

    Citation: BMC Infectious Diseases 2006 6:57

    Content type: Research article

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  34. For its low cost and ease of handling, the mouse remains the preferred experimental animal for preclinical tests. To avoid the interaction of the animal immune system, in vivo antibiotic pharmacodynamic studie...

    Authors: Andres F Zuluaga, Beatriz E Salazar, Carlos A Rodriguez, Ana X Zapata, Maria Agudelo and Omar Vesga

    Citation: BMC Infectious Diseases 2006 6:55

    Content type: Research article

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  35. The role of Diabetes mellitus (DM) in the etiology and in the antimicrobial resistance of uropathogens in patients with urinary tract infection has not been well clarified. For this reason we have evaluated th...

    Authors: Mario Bonadio, Silvia Costarelli, Giovanna Morelli and Tiziana Tartaglia

    Citation: BMC Infectious Diseases 2006 6:54

    Content type: Research article

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  36. Bloodstream infection (BSI) due to Pseudomonas aeruginosa (Pa) has relevant clinical impact especially in relation to drug resistance determinants. The PER-1 extended-spectrum beta-lactamase (ESBL) is a common...

    Authors: Andrea Endimiani, Francesco Luzzaro, Beatrice Pini, Gianfranco Amicosante, Gian Maria Rossolini and Antonio Q Toniolo

    Citation: BMC Infectious Diseases 2006 6:52

    Content type: Research article

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  37. Previous studies have indicated that a recently described anaerobic bacterium, Atopobium vaginae is associated with bacterial vaginosis (BV). Thus far the four isolates of this fastidious micro-organism were foun...

    Authors: Ellen De Backer, Rita Verhelst, Hans Verstraelen, Geert Claeys, Gerda Verschraegen, Marleen Temmerman and Mario Vaneechoutte

    Citation: BMC Infectious Diseases 2006 6:51

    Content type: Research article

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  38. Most of the studies about invasive Candida infections in cancer patients have focused on haematological patients. The aim of this study was to provide information about risk factors for candidaemia in patients wi...

    Authors: Alessandro Comarú Pasqualotto, Daniela Dornelles Rosa, Lidia Rosi Medeiros and Luiz Carlos Severo

    Citation: BMC Infectious Diseases 2006 6:50

    Content type: Research article

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  39. Haematogenous Staphylococcus aureus meningitis is rare but associated with high mortality. Knowledge about the disease is still limited. The objective of this study was to evaluate demographic and clinical progno...

    Authors: Michael Pedersen, Thomas L Benfield, Peter Skinhoej and Allan G Jensen

    Citation: BMC Infectious Diseases 2006 6:49

    Content type: Research article

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  40. The whole-blood interferon-gamma release assay (IGRA) is recommended in some settings as an alternative to the tuberculin skin test (TST). Outcomes from field implementation of the IGRA for routine tuberculosi...

    Authors: Puneet Kumar Dewan, Jennifer Grinsdale, Sally Liska, Ernest Wong, Robert Fallstad and L Masae Kawamura

    Citation: BMC Infectious Diseases 2006 6:47

    Content type: Research article

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