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Viral diseases

Section edited by Jodie McVernon and Julian Tang

This section aims to publish studies looking at all aspects of of the prevention, diagnosis and management of viral diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. HIV, HIV-associated infections and sexually transmitted diseases are considered in separate sections.

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  1. Content type: Research article

    Ethiopia joined the Global Polio Eradication Initiative (GPEI) in 1996, and by the end of December 2001 circulation of indigenous Wild Polio Virus (WPV) had been interrupted. Nonetheless, the country experienc...

    Authors: Ayesheshem Ademe Tegegne, Fiona Braka, Meseret Eshetu Shebeshi, Aron Kassahun Aregay, Berhane Beyene, Amare Mengistu Mersha, Mohammed Ademe, Abdulahi Muhyadin, Dadi Jima and Abyot Bekele Wyessa

    Citation: BMC Infectious Diseases 2018 18:9

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  2. Content type: Research article

    According to the global framework of eliminating human rabies, China is responding to achieve the target of zero human death from dog-mediated rabies by 2030. Chongqing is the largest municipality directly und...

    Authors: Li Qi, Kun Su, Tao Shen, Wenge Tang, Bangzhong Xiao, Jiang Long, Han Zhao, Xi Chen, Yu Xia, Yu Xiong, Dayong Xiao, Liangui Feng and Qin Li

    Citation: BMC Infectious Diseases 2018 18:6

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  3. Content type: Research article

    Central nervous system (CNS) infections are an important cause of childhood morbidity and mortality. The aetiologies of these potentially vaccine-preventable infections have not been well established in Cambodia.

    Authors: Paul Turner, Kuong Suy, Le Van Tan, Pora Sar, Thyl Miliya, Nguyen Thi Thu Hong, Vu Thi Ty Hang, Nguyen Thi Han Ny, Sona Soeng, Nicholas P. J. Day, H. Rogier van Doorn and Claudia Turner

    Citation: BMC Infectious Diseases 2017 17:806

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  4. Content type: Research article

    Respiratory syncytial virus (RSV) infection constitutes a substantial disease burden in the general population. However, the risk of death for RSV infection has been rarely evaluated with confounders or comorb...

    Authors: Yong Shik Kwon, Sun Hyo Park, Mi-Ae Kim, Hyun Jung Kim, Jae Seok Park, Mi Young Lee, Choong Won Lee, Sonila Dauti and Won-Il Choi

    Citation: BMC Infectious Diseases 2017 17:785

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  5. Content type: Research article

    The recent emergence of Zika virus (ZIKV) in Brazil and its precipitous expansion throughout the Americas has highlighted the urgent need for a rapid and reliable on-site diagnostic assay suitable for viral de...

    Authors: Mariano Carossino, Yanqiu Li, Pei-Yu A. Lee, Chuan-Fu Tsai, Pin-Hsing Chou, Dennis Williams, Ashley Skillman, R. Frank Cook, Grayson Brown, Hsiao-Fen G. Chang, Hwa-Tang T. Wang and Udeni B. R. Balasuriya

    Citation: BMC Infectious Diseases 2017 17:778

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  6. Content type: Research article

    Mathematical models offer the possibility to investigate the infectious disease dynamics over time and may help in informing design of studies. A systematic review was performed in order to determine to what e...

    Authors: Sereina A. Herzog, Stéphanie Blaizot and Niel Hens

    Citation: BMC Infectious Diseases 2017 17:775

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  7. Content type: Research article

    Unlike influenza viruses, little is known about the prevalence and seasonality of other respiratory viruses because laboratory surveillance for non-influenza respiratory viruses is not well developed or suppor...

    Authors: Xueying Zheng, Zhengyu Song, Yapeng Li, Juanjuan Zhang and Xi-Ling Wang

    Citation: BMC Infectious Diseases 2017 17:772

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  8. Content type: Research article

    Respiratory syncytial virus (RSV) is the most important cause of severe acute respiratory tract infection in young children. Alere i RSV is a novel molecular rapid test which identifies respiratory syncytial v...

    Authors: Sarah Valerie Schnee, Johannes Pfeil, Clara Marlene Ihling, Julia Tabatabai and Paul Schnitzler

    Citation: BMC Infectious Diseases 2017 17:767

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  9. Content type: Research article

    This cross-sectional study evaluated the prevalence of infection with human T-lymphotropic virus 1 and 2 (HTLV-1 and HTLV-2) in a population from the municipalities of Anajás, Chaves, São Sebastião da Boa Vist...

    Authors: Samantha Assis de Aguiar, Samires Avelino de Souza França, Barbara Brasil Santana, Mike Barbosa Santos, Felipe Bonfim Freitas, Glenda Ferreira, Izaura Cayres-Vallinoto, Marluísa O. G. Ishak, Ricardo Ishak and Antonio Carlos Rosário Vallinoto

    Citation: BMC Infectious Diseases 2017 17:758

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  10. Content type: Research article

    Disease burden attributable to influenza is substantial in subtropical regions. Our study aims to estimate excess pneumonia and influenza (P&I) mortality associated with influenza by subtypes/lineages in Shang...

    Authors: Xinchun Yu, Chunfang Wang, Tao Chen, Wenyi Zhang, Huiting Yu, Yuelong Shu, Wenbiao Hu and Xiling Wang

    Citation: BMC Infectious Diseases 2017 17:756

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  11. Content type: Research article

    Various viruses are known to be associated with pneumonia. However, the impact of viral infections on adult pneumonia mortality remains unclear. This study aimed to clarify the effect of virus infection on pne...

    Authors: Naoko Katsurada, Motoi Suzuki, Masahiro Aoshima, Makito Yaegashi, Tomoko Ishifuji, Norichika Asoh, Naohisa Hamashige, Masahiko Abe, Koya Ariyoshi and Konosuke Morimoto

    Citation: BMC Infectious Diseases 2017 17:755

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  12. Content type: Research article

    Cytomegalovirus (CMV) infection and disease (CMV episodes) are global concerns after allogeneic hematopoietic stem cell transplantation (HSCT). They affect survival, both by direct and indirect effects. Due to...

    Authors: Christine Robin, François Hémery, Christel Dindorf, Julien Thillard, Ludovic Cabanne, Rabah Redjoul, Florence Beckerich, Christophe Rodriguez, Cécile Pautas, Andrea Toma, Sébastien Maury, Isabelle Durand-Zaleski and Catherine Cordonnier

    Citation: BMC Infectious Diseases 2017 17:747

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  13. Content type: Research article

    Over the last decade, capacity for influenza surveillance and research in West Africa has strengthened. Data from these surveillance systems showed influenza A(H1N1)pdm09 circulated in West Africa later than i...

    Authors: Ndahwouh Talla Nzussouo, Jazmin Duque, Adebayo Abel Adedeji, Daouda Coulibaly, Samba Sow, Zekiba Tarnagda, Issaka Maman, Adamou Lagare, Sonia Makaya, Mohamed Brahim Elkory, Herve Kadjo Adje, Paul Alhassan Shilo, Boubou Tamboura, Assana Cisse, Kossi Badziklou, Halima Boubacar Maïnassara…

    Citation: BMC Infectious Diseases 2017 17:745

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  14. Content type: Research article

    The goal of polio eradication is to complete elimination and containment of all wild, vaccine-related and Sabin polioviruses. Vaccine-derived poliovirus (VDPV) surveillance in China from 2001–2013 is summarize...

    Authors: Hai-Bo Wang, Hui-Ming Luo, Li Li, Chun-Xiang Fan, Li-Xin Hao, Chao Ma, Qi-Ru Su, Hong Yang, Kathleen H. Reilly, Hua-Qing Wang and Ning Wen

    Citation: BMC Infectious Diseases 2017 17:742

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  15. Content type: Research article

    Human papillomavirus (HPV) associated malignancies are the leading cause of cancer death in Botswana. We sought to determine causative HPV types in patients with anogenital malignancies in Botswana to inform v...

    Authors: Patricia S. Rantshabeng, Sikhulile Moyo, Natasha O. Moraka, Andrew Ndlovu, Iain J. MacLeod, Simani Gaseitsiwe and Ishmael Kasvosve

    Citation: BMC Infectious Diseases 2017 17:731

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  16. Content type: Research article

    Gastrointestinal (GI) symptoms, such as diarrhea, vomiting, abdominal pain and nausea are not an uncommon manifestation of an acute respiratory infection (ARI).

    Authors: Laetitia Minodier, Shirley Masse, Lisandru Capai, Thierry Blanchon, Pierre-Emmanuel Ceccaldi, Sylvie van der Werf, Thomas Hanslik, Remi Charrel and Alessandra Falchi

    Citation: BMC Infectious Diseases 2017 17:729

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  17. Content type: Research article

    Varicella zoster virus (VZV) causes varicella and herpes zoster. These vaccine preventable diseases are common globally. Most available data on VZV epidemiology are from industrialised temperate countries and ...

    Authors: Hannah Hussey, Leila Abdullahi, Jamie Collins, Rudzani Muloiwa, Gregory Hussey and Benjamin Kagina

    Citation: BMC Infectious Diseases 2017 17:717

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  18. Content type: Research article

    From 31 August to 9 September 2015, a total of 150 military personnel at a military institution in Singapore were infected with acute gastroenteritis (AGE) with an attack rate of approximately 3%. This study a...

    Authors: Freddy Jun Xian Neo, Jimmy Jin Phang Loh, Peijun Ting, Wei Xin Yeo, Christine Qiu Han Gao, Vernon Jian Ming Lee, Boon Huan Tan and Ching Ging Ng

    Citation: BMC Infectious Diseases 2017 17:719

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  19. Content type: Research article

    There is global health concern that the mass movement of pilgrims to and from Mecca annually could contribute to the international spread of Middle East Respiratory Syndrome Coronavirus (MERS-CoV). In China, a...

    Authors: Xuezheng Ma, Fang Liu, Lijuan Liu, Liping Zhang, Mingzhu Lu, Abuduzhayier Abudukadeer, Lingbing Wang, Feng Tian, Wei Zhen, Pengfei Yang and Kongxin Hu

    Citation: BMC Infectious Diseases 2017 17:715

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  20. Content type: Research article

    A large number (n = 460) of A(H7N9) human infections have been reported in China from March 2013 through December 2014, and H7N9 outbreaks in humans became an emerging issue for China health, which have caused nu...

    Authors: Wen Dong, Kun Yang, Quanli Xu, Lin Liu and Juan Chen

    Citation: BMC Infectious Diseases 2017 17:704

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  21. Content type: Research article

    Cytomegalovirus (CMV) is a common cause of congenital infection worldwide and infants with symptomatic congenital CMV (cCMV) infection are at significantly increased risk of developing adverse long-term outcom...

    Authors: Mina Ebrahimi-Rad, Talayeh Seyed Shakeri, Fariba Shirvani, Kiana Shahrokhi and Nader Shahrokhi

    Citation: BMC Infectious Diseases 2017 17:688

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  22. Content type: Research article

    This study aimed at estimating the efficiency of palivizumab in the prevention of Respiratory Syncytial Virus (RSV) infection and its sequelae in preterm infants (32day 1-35day 0weeks of gestational age –wGA-) in...

    Authors: M. Sanchez-Luna, R. Burgos-Pol, I. Oyagüez, J. Figueras-Aloy, M. Sánchez-Solís, F. Martinón-Torres and X. Carbonell-Estrany

    Citation: BMC Infectious Diseases 2017 17:687

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  23. Content type: Research article

    Norovirus is a common cause of infectious gastrointestinal disease. Despite the increased ability to detect norovirus in affected people, the number of reported cases and outbreaks in the community is still su...

    Authors: Thomas Inns, John Harris, Roberto Vivancos, Miren Iturriza-Gomara and Sarah O’Brien

    Citation: BMC Infectious Diseases 2017 17:657

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  24. Content type: Research article

    Hand-foot-mouth disease (HFMD) is an acute infectious disease caused by enteroviruses, and HFMD complicated by cardiopulmonary failure has a high mortality. B type natriuretic peptide (BNP) is widely applied i...

    Authors: AYuan Zhang, Lin Yang, Pengfei Guo, Shaojun Li, Xiaoxiao Ao, Feng Xu and Liping Tan

    Citation: BMC Infectious Diseases 2017 17:651

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  25. Content type: Research article

    A global pandemic mortality study found prominent regional mortality variations in 2009 for Influenza A(H1N1)pdm09. Our study attempts to identify factors that explain why the pandemic mortality burden was hig...

    Authors: Kathleen F. Morales, John Paget and Peter Spreeuwenberg

    Citation: BMC Infectious Diseases 2017 17:642

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  26. Content type: Research article

    Hand, foot and mouth disease (HFMD) is one of the highest reported infectious diseases with several outbreaks across the world. This study aimed at describing epidemiological characteristics, investigating spa...

    Authors: Xinrui Wu, Shixiong Hu, Abuaku Benjamin Kwaku, Qi Li, Kaiwei Luo, Ying Zhou and Hongzhuan Tan

    Citation: BMC Infectious Diseases 2017 17:645

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  27. Content type: Research article

    Models of infectious disease are increasingly utilising empirical contact data to quantify the number of potentially infectious contacts between age groups. While a growing body of data is being collected on c...

    Authors: Patricia Therese Campbell, Jodie McVernon, Niraj Shrestha, Paula M. Nathan and Nicholas Geard

    Citation: BMC Infectious Diseases 2017 17:634

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  28. Content type: Research article

    Protective antibody immunity against the influenza A virus wanes in 2–7 years due to antigenic drift of the virus’ surface proteins. The duration of immune protection is highly variable because antigenic evolu...

    Authors: Rutger G. Woolthuis, Jacco Wallinga and Michiel van Boven

    Citation: BMC Infectious Diseases 2017 17:632

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  29. Content type: Research article

    Hepatitis C (HCV) infection causes an asymptomatic chronic hepatitis in most affected individuals, which often remains undetected until cirrhosis and cirrhosis-related complications occur. Screening of high-ri...

    Authors: H. Kileng, L. Bernfort, T. Gutteberg, O.S. Moen, M.G. Kristiansen, E.J. Paulssen, L.K. Berg, J. Florholmen and R. Goll

    Citation: BMC Infectious Diseases 2017 17:624

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  30. Content type: Research article

    Varicella or chickenpox was not a notifiable disease until 2005 in Sri Lanka and only a few studies have been conducted on the epidemiology of VZV infection in the country. The anti­VZV IgG sero-prevalence amo...

    Authors: Saluwadana Walawwe Pavithra Lakmini Daulagala, Faseeha Noordeen, Mohamed Mukthar Fathina Fara, Chathura Rathnayake and Kapila Gunawardana

    Citation: BMC Infectious Diseases 2017 17:625

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  31. Content type: Research Article

    Individual-based models (IBMs) are useful to simulate events subject to stochasticity and/or heterogeneity, and have become well established to model the potential (re)emergence of pathogens (e.g., pandemic in...

    Authors: Lander Willem, Frederik Verelst, Joke Bilcke, Niel Hens and Philippe Beutels

    Citation: BMC Infectious Diseases 2017 17:612

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  32. Content type: Research article

    Clinical syndromes associated with West Nile virus (WNV) infection range from fever to neuroinvasive disease. Understanding WNV epidemiology and disease history is important for guiding patient care and health...

    Authors: Man Wah Yeung, Emily Shing, Mark Nelder and Beate Sander

    Citation: BMC Infectious Diseases 2017 17:609

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  33. Content type: Research article

    Rabies is a global fatal infectious viral disease that is characterized by a high mortality after onset of clinical symptoms. Recently, there has been an increase in the incidence of rabies in China. The aim o...

    Authors: Jian-Ming Zhang, Zhi-Shan Zhang, Yan-Qin Deng, Shou-Li Wu, Wei Wang and Yan-Sheng Yan

    Citation: BMC Infectious Diseases 2017 17:599

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  34. Content type: Case report

    During the 2013–2016 West Africa Ebola virus disease (EVD) epidemic, some EVD patients, mostly health care workers, were evacuated to Europe and the USA.

    Authors: Emanuele Nicastri, Antonio Brucato, Nicola Petrosillo, Gianluigi Biava, Timothy M. Uyeki and Giuseppe Ippolito

    Citation: BMC Infectious Diseases 2017 17:597

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  35. Content type: Research article

    Rapid immunochromatographic tests (ICT) for dengue non-structural protein 1 (NS1) have shown good performance for diagnosing acute-phase dengue in serum in laboratory settings, but rarely have been assessed in...

    Authors: Verónica Elizabeth Mata, Sonia Regina Lambert Passos, Yara Hahr Marques Hökerberg, Guilherme Miguéis Berardinelli, Maria Angelica Borges dos Santos, Levy Vilas Boas Fukuoka, Anna Carolina Fontoura Seixas Rangel Maciel, Cintia Damasceno dos Santos Rodrigues, Aline da Silva Santos and Raquel de Vasconcellos Carvalhaes de Oliveira

    Citation: BMC Infectious Diseases 2017 17:594

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    The Correction to this article has been published in BMC Infectious Diseases 2017 17:710

  36. Content type: Research article

    Respiratory diseases cause substantial morbidity and mortality worldwide, with sub-Saharan Africa bearing the greatest burden. Identifying etiologies of respiratory disease is important to inform cost effectiv...

    Authors: Henry N. Njuguna, Sandra S. Chaves, Gideon O. Emukule, Bryan Nyawanda, Victor Omballa, Bonventure Juma, Clayton O. Onyango, Joshua A. Mott and Barry Fields

    Citation: BMC Infectious Diseases 2017 17:591

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  37. Content type: Research article

    Human influenza represents a major public health concern, especially in south-east Asia where the risk of emergence and spread of novel influenza viruses is particularly high. The BaliMEI study aims to conduct...

    Authors: W. Adisasmito, S. N. Budayanti, D. N. Aisyah, T. Gallo Cassarino, J. W. Rudge, S. J. Watson, Z. Kozlakidis, G. J. D. Smith and R. Coker

    Citation: BMC Infectious Diseases 2017 17:583

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  38. Content type: Case report

    Some reported that organizing pneumonia (OP) may occur after influenza A infections including swine-origin influenza A (H1N1). However, OP associated with influenza B infection has never been reported. We repo...

    Authors: Nobuhiro Asai, Toyoharu Yokoi, Naoya Nishiyama, Yusuke Koizumi, Daisuke Sakanashi, Hideo Kato, Mao Hagihara, Hiroyuki Suematsu, Yuka Yamagishi and Hiroshige Mikamo

    Citation: BMC Infectious Diseases 2017 17:572

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  39. Content type: Research article

    Chickenpox is a common contagious disease that remains an important public health issue worldwide. Over 90% of unvaccinated individuals become infected, but infection occurs at different ages in different part...

    Authors: Banghua Chen, Ayako Sumi, Lei Wang, Wang Zhou and Nobumichi Kobayashi

    Citation: BMC Infectious Diseases 2017 17:538

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  40. Content type: Research article

    Severe fever with thrombocytopenia syndrome (SFTS) was first reported in China in 2011. Human-to-human transmission of the virus occurred occasionally in family clusters. However, pneumonia as an onset syndrom...

    Authors: Yiyi Zhu, Huanyu Wu, Jie Gao, Xin Zhou, Renyi Zhu, Chunzhe Zhang, Hongling Bai, Abu S. Abdullah and Hao Pan

    Citation: BMC Infectious Diseases 2017 17:537

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  41. Content type: Research article

    To predict the risk of infectious diseases originating in wildlife, it is important to identify habitats that allow the co-occurrence of pathogens and their hosts. Puumala hantavirus (PUUV) is a directly-trans...

    Authors: Hussein Khalil, Gert Olsson, Magnus Magnusson, Magnus Evander, Birger Hörnfeldt and Frauke Ecke

    Citation: BMC Infectious Diseases 2017 17:523

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  42. Content type: Research article

    Zika virus, an emerging serious infectious disease, is a threat to persons living or travelling to regions where it is currently endemic, and also to contacts of infected individuals. The aim of this study was...

    Authors: Sohaila Cheema, Patrick Maisonneuve, Ingmar Weber, Luis Fernandez-Luque, Amit Abraham, Hekmat Alrouh, Javaid Sheikh, Albert B. Lowenfels and Ravinder Mamtani

    Citation: BMC Infectious Diseases 2017 17:524

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  43. Content type: Research article

    Mixing patterns of human populations play a crucial role in shaping the spreading paths of infectious diseases. The diffusion of mobile and wearable devices able to record close proximity interactions represen...

    Authors: Piero Poletti, Roberto Visintainer, Bruno Lepri and Stefano Merler

    Citation: BMC Infectious Diseases 2017 17:521

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