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Viral diseases

Section edited by Julian Tang

This section aims to publish studies looking at all aspects of of the prevention, diagnosis and management of viral diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. HIV, HIV-associated infections and sexually transmitted diseases are considered in separate sections.

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  1. The role of Epstein-Barr (EBV) virus in central nervous system (CNS) infections is not fully resolved. It is clearly associated with lymphoproliferative disease of immunosuppressed persons, and may cause encep...

    Authors: Timi Martelius, Maija Lappalainen, Maarit Palomäki and Veli-Jukka Anttila

    Citation: BMC Infectious Diseases 2011 11:281

    Content type: Research article

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  2. The association of hepatitis B virus (HBV) genotypes/subgenotypes with clinical characteristics is increasingly recognized. However, the virologic and clinical features of HBV genotypes/subgenotypes in pediatr...

    Authors: Yan-Wei Zhong, Jin Li, Hong-Bin Song, Zhong-Ping Duan, Yi Dong, Xiao-Yan Xing, Xiao-Dong Li, Mei-Lei Gu, Yu-Kun Han, Shi-Shu Zhu and Hong-Fei Zhang

    Citation: BMC Infectious Diseases 2011 11:262

    Content type: Research article

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  3. Localized reactive school and classroom closures were implemented as part of a suite of pandemic containment measures during the initial response to influenza A (H1N1) 2009 in Melbourne, Australia. Infected in...

    Authors: Jodie McVernon, Kate Mason, Sylvia Petrony, Paula Nathan, Anthony D LaMontagne, Rebecca Bentley, James Fielding, David M Studdert and Anne Kavanagh

    Citation: BMC Infectious Diseases 2011 11:257

    Content type: Research article

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  4. Data on complications in children with seasonal influenza virus infection are limited. We initiated a nation-wide three-year surveillance of children who were admitted to a paediatric intensive care unit (PICU...

    Authors: Andrea Streng, Veit Grote and Johannes G Liese

    Citation: BMC Infectious Diseases 2011 11:233

    Content type: Research article

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  5. Severe disease caused by 2009 pandemic influenza A/H1N1virus is characterized by the presence of hypercytokinemia. The origin of the exacerbated cytokine response is unclear. As observed previously, uncontroll...

    Authors: Raquel Almansa, Andres Anton, Paula Ramirez, Ignacio Martin-Loeches, David Banner, Tomás Pumarola, Luoling Xu, Jesús Blanco, Longsi Ran, Guillermo Lopez-Campos, Fernando Martin-Sanchez, Lorenzo Socias, Ana Loza, David Andaluz, Enrique Maravi, Mónica Gordón…

    Citation: BMC Infectious Diseases 2011 11:232

    Content type: Research article

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  6. There was a pandemic influenza around the world in 2009 including South Korea since last pandemic occurred four decades ago. We aimed to evaluate the epidemiological and clinical characteristics of this infect...

    Authors: Jung-Woo Rhim, Kyung-Yil Lee, You-Sook Youn, Jin-Han Kang and Ji-Chang Kim

    Citation: BMC Infectious Diseases 2011 11:225

    Content type: Research article

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  7. Infections of the central nervous system (CNS) with herpes- or enterovirus can be self-limiting and benign, but occasionally result in severe and fatal disease. The polymerase chain reaction (PCR) has revoluti...

    Authors: Birgitta Sundén, Marie Larsson, Tina Falkeborn, Jakob Paues, Urban Forsum, Magnus Lindh, Liselotte Ydrenius, Britt Åkerlind and Lena Serrander

    Citation: BMC Infectious Diseases 2011 11:220

    Content type: Research article

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  8. Our aim was to characterize clinical properties and laboratory parameters in patients with or without cerebrospinal fluid (CSF) findings suggestive of central nervous system (CNS) involvement, and especially t...

    Authors: Timo Hautala, Nina Hautala, Saara-Mari Mähönen, Tarja Sironen, Eija Pääkkö, Ari Karttunen, Pasi I Salmela, Olli Vainio, Seppo Rytky, Alexander Plyusnin, Antti Vaheri, Olli Vapalahti and Heikki Kauma

    Citation: BMC Infectious Diseases 2011 11:217

    Content type: Research article

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  9. While dengue-elicited early and transient host responses preceding defervescence could shape the disease outcome and reveal mechanisms of the disease pathogenesis, assessment of these responses are difficult a...

    Authors: Thomas Tolfvenstam, Anna Lindblom, Mark J Schreiber, Ling Ling, Angelia Chow, Eng Eong Ooi and Martin L Hibberd

    Citation: BMC Infectious Diseases 2011 11:209

    Content type: Research article

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  10. Hepatitis C virus (HCV) genotype (GT) has become an important measure in the diagnosis and monitoring of HCV infection treatment. In the United States (U.S.) HCV GT 1 is reported as the most common infecting G...

    Authors: Paulo Telles Dias, Judith A Hahn, Eric Delwart, Brian R Edlin, Jeff Martin, Paula Lum, Jennifer Evans, Alex Kral, Steve Deeks, Michael P Busch and Kimberly Page

    Citation: BMC Infectious Diseases 2011 11:208

    Content type: Research article

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  11. Influenza virus is a major cause of respiratory disease worldwide and Streptococcus pneumoniae infection associated with influenza often leads to severe complications. Dendritic cells are key antigen presenting c...

    Authors: Yuet Wu, Huawei Mao, Man-To Ling, Kin-Hung Chow, Pak-Leung Ho, Wenwei Tu and Yu-Lung Lau

    Citation: BMC Infectious Diseases 2011 11:201

    Content type: Research article

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  12. Complex mutants can be selected under sequential selective pressure by HBV therapy. To determine hepatitis B virus genomic evolution during antiviral therapy we characterized the HBV quasi-species in a patient...

    Authors: Lucila Cassino, Silvina Benetti, Fabian Fay, Hugo Tanno and Jorge Quarleri

    Citation: BMC Infectious Diseases 2011 11:178

    Content type: Case report

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  13. The effect of peginterferon and ribavirin treatment on chronic hepatitis C virus (HCV) infection has been established in several controlled clinical studies. However, the effectiveness of treatment and predict...

    Authors: Nanna Hansen, Niels Obel, Peer B Christensen, Mette Kjær, Alex L Laursen, Henrik B Krarup, Axel Møller, Poul Schlichting, Jens Bukh and Nina Weis

    Citation: BMC Infectious Diseases 2011 11:177

    Content type: Research article

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  14. Herpes zoster (HZ) is caused by a reactivation of the varicella-zoster-virus (VZV) and mainly affects individuals aged ≥ 50 years. Vaccines have been licensed or are under development that can protect against ...

    Authors: Bernhard Ultsch, Anette Siedler, Thorsten Rieck, Thomas Reinhold, Gérard Krause and Ole Wichmann

    Citation: BMC Infectious Diseases 2011 11:173

    Content type: Research article

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  15. Recent studies strongly suggest that some respiratory viruses are associated with the induction of acute wheezing and/or exacerbation of bronchial asthma. However, molecular epidemiology of these viruses is no...

    Authors: Asako Fujitsuka, Hiroyuki Tsukagoshi, Mika Arakawa, Kazuko Goto-Sugai, Akihide Ryo, Yoshimichi Okayama, Katsumi Mizuta, Atsuyoshi Nishina, Masakazu Yoshizumi, Yoichi Kaburagi, Masahiro Noda, Masato Tashiro, Nobuhiko Okabe, Masaaki Mori, Shumpei Yokota and Hirokazu Kimura

    Citation: BMC Infectious Diseases 2011 11:168

    Content type: Research article

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  16. Interferon alpha (IFNα) therapy has been widely used in the treatment of chronic hepatitis B (CHB) for decades. Nucleos(t)ide analogues are also increasingly used to treat CHB recently. More and more studies a...

    Authors: Wen-cong Li, Mao-rong Wang, Ling-bo Kong, Wei-guang Ren, Yu-guo Zhang and Yue-min Nan

    Citation: BMC Infectious Diseases 2011 11:165

    Content type: Research article

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  17. Acute otitis media with perforation (AOMwiP) affects 40% of remote Indigenous children during the first 18 months of life. Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis are the primar...

    Authors: Michael J Binks, Allen C Cheng, Heidi Smith-Vaughan, Theo Sloots, Michael Nissen, David Whiley, Joseph McDonnell and Amanda J Leach

    Citation: BMC Infectious Diseases 2011 11:161

    Content type: Research article

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  18. In the United States, about 70% of 2.9-3.7 million people with hepatitis C (HCV) are unaware of their infection. Although universal screening might be a cost-effective way to identify infections, prevent morbi...

    Authors: Phillip O Coffin, Anne M Stevens, John D Scott, Joanne D Stekler and Matthew R Golden

    Citation: BMC Infectious Diseases 2011 11:160

    Content type: Research article

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  19. Norway is classified as a low prevalence country for hepatitis B virus infection. Vaccination is only recommended for risk groups (intravenous drug users (IDUs), Men who have Sex with Men (MSM), immigrants and...

    Authors: Gražina Rimšelienė, Øivind Nilsen, Hilde Kløvstad, Hans Blystad and Preben Aavitsland

    Citation: BMC Infectious Diseases 2011 11:153

    Content type: Research article

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  20. Viral reservoir size refers to cellular human immunodeficiency virus-1 (HIV-1) DNA levels in CD4+ T lymphocytes of peripheral blood obtained from patients with plasma HIV-1-RNA levels (viral load, VL) maintained ...

    Authors: Dai Watanabe, Shiro Ibe, Tomoko Uehira, Rumi Minami, Atsushi Sasakawa, Keishiro Yajima, Hitoshi Yonemoto, Hiroki Bando, Yoshihiko Ogawa, Tomohiro Taniguchi, Daisuke Kasai, Yasuharu Nishida, Masahiro Yamamoto, Tsuguhiro Kaneda and Takuma Shirasaka

    Citation: BMC Infectious Diseases 2011 11:146

    Content type: Research article

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  21. Hantaviruses are the causative agents of two zoonotic diseases: hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). The pathogenesis of HFRS is poorly understood. Howev...

    Authors: Ana Saksida, Branka Wraber and Tatjana Avšič-Županc

    Citation: BMC Infectious Diseases 2011 11:142

    Content type: Research article

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  22. The World Health Organization recommends universal and quality-controlled screening of blood donations for the major transfusion-transmissible infections (TTIs): human immunodeficiency virus (HIV), hepatitis B...

    Authors: Jocelijn Stokx, Philippe Gillet, Anja De Weggheleire, Esther C Casas, Rosa Maendaenda, Adelino J Beulane, Ilhes V Jani, Solon Kidane, Carla D Mosse, Jan Jacobs and Emmanuel Bottieau

    Citation: BMC Infectious Diseases 2011 11:141

    Content type: Research article

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  23. Dengue re-emerges in Singapore despite decades of effective vector control; the infection predominantly afflicts adults. Severe dengue not fulfilling dengue hemorrhagic fever (DHF) criteria according to World ...

    Authors: Yee-Sin Leo, Tun L Thein, Dale A Fisher, Jenny G Low, Helen M Oh, Rajmohan L Narayanan, Victor C Gan, Vernon J Lee and David C Lye

    Citation: BMC Infectious Diseases 2011 11:123

    Content type: Research article

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  24. The swine influenza H1N1 first identified in Mexico, spread rapidly across the globe and is considered the fastest moving pandemic in history. The early phase of an outbreak, in which data is relatively scarce...

    Authors: Uri Roll, Rami Yaari, Guy Katriel, Oren Barnea, Lewi Stone, Ella Mendelson, Michal Mandelboim and Amit Huppert

    Citation: BMC Infectious Diseases 2011 11:92

    Content type: Research article

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