Viral diseases

Section edited by Jodie McVernon and Julian Tang

This section aims to publish studies looking at all aspects of of the prevention, diagnosis and management of viral diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. HIV, HIV-associated infections and sexually transmitted diseases are considered in separate sections.

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  1. Research article

    Knowledge and perceptions about Zika virus in a Middle East country

    Zika virus, an emerging serious infectious disease, is a threat to persons living or travelling to regions where it is currently endemic, and also to contacts of infected individuals. The aim of this study was...

    Sohaila Cheema, Patrick Maisonneuve, Ingmar Weber, Luis Fernandez-Luque, Amit Abraham, Hekmat Alrouh, Javaid Sheikh, Albert B. Lowenfels and Ravinder Mamtani

    BMC Infectious Diseases 2017 17:524

    Published on: 26 July 2017

  2. Research article

    Spatial prediction and validation of zoonotic hazard through micro-habitat properties: where does Puumala hantavirus hole – up?

    To predict the risk of infectious diseases originating in wildlife, it is important to identify habitats that allow the co-occurrence of pathogens and their hosts. Puumala hantavirus (PUUV) is a directly-trans...

    Hussein Khalil, Gert Olsson, Magnus Magnusson, Magnus Evander, Birger Hörnfeldt and Frauke Ecke

    BMC Infectious Diseases 2017 17:523

    Published on: 26 July 2017

  3. Research article

    GeneXpert HIV-1 quant assay, a new tool for scale up of viral load monitoring in the success of ART programme in India

    Recent WHO guidelines identify virologic monitoring for diagnosing and confirming ART failure. In view of this, validation and scale up of point of care viral load technologies is essential in resource limited...

    Smita Kulkarni, Sushama Jadhav, Priyanka Khopkar, Suvarna Sane, Rajkumar Londhe, Vaishali Chimanpure, Veronica Dhilpe, Manisha Ghate, Rajendra Yelagate, Narayan Panchal, Girish Rahane, Dilip Kadam, Nitin Gaikwad, Bharat Rewari and Raman Gangakhedkar

    BMC Infectious Diseases 2017 17:506

    Published on: 21 July 2017

  4. Research article

    Evaluation of creatine kinase and liver enzymes in identification of severe dengue

    Existing biomarkers such as AST, ALT and hematocrit have been associated with severe dengue but evidence are mixed. Recently, interests in creatine kinase as a dengue biomarker have risen. These biomarkers rep...

    Saiful Safuan Md Sani, Winn Hui Han, Mohamad Adam Bujang, Hui Jen Ding, Kiah Loon Ng and Mohd Azizuddin Amir Shariffuddin

    BMC Infectious Diseases 2017 17:505

    Published on: 21 July 2017

  5. Research article

    Comparing patient and healthcare worker experiences during a dengue outbreak in Singapore: understanding the patient journey and the introduction of a point-of-care test (POCT) toward better care delivery

    In the aftermath of an upsurge in the number of dengue cases in 2013 and 2014, the SD BIOLINE Dengue Duo rapid diagnostic Point-of-Care Test (POCT) kit was introduced in Tan Tock Seng Hospital, Singapore in June ...

    Qinghui Tan, Zoe J-L Hildon, Shweta Singh, Jin Jing, Tun Linn Thein, Richard Coker, Hubertus J. M. Vrijhoef and Yee Sin Leo

    BMC Infectious Diseases 2017 17:503

    Published on: 19 July 2017

  6. Research article

    Cytomegalovirus viraemia and mortality in renal transplant recipients in the era of antiviral prophylaxis. Lessons from the western Australian experience

    Cytomegalovirus (CMV) establishes a lifelong infection that is efficiently controlled by the immune system; this infection can be reactivated in case of immunosuppression such as following solid organ transpla...

    Linda A. Selvey, Wai H. Lim, Peter Boan, Ramyasuda Swaminathan, Claudia Slimings, Amy E. Harrison and Aron Chakera

    BMC Infectious Diseases 2017 17:501

    Published on: 17 July 2017

  7. Research article

    Etiology and prognosis of acute viral encephalitis and meningitis in Chinese children: a multicentre prospective study

    In China, there were few studies about the pathogens of acute viral encephalitis and meningitis in children in recent years. The aims of this study were to characterize the etiology and prognosis of acute vira...

    Junhong Ai, Zhengde Xie, Gang Liu, Zongbo Chen, Yong Yang, Yuning Li, Jing Chen, Guo Zheng and Kunling Shen

    BMC Infectious Diseases 2017 17:494

    Published on: 14 July 2017

  8. Case report

    The clinical and virological features of the first imported case causing MERS-CoV outbreak in South Korea, 2015

    In 2015, the largest outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) infection outside the Middle East occurred in South Korea. We summarized the epidemiological, clinical, and laboratory f...

    Ji Yeon Lee, You-Jin Kim, Eun Hee Chung, Dae-Won Kim, Ina Jeong, Yeonjae Kim, Mi-ran Yun, Sung Soon Kim, Gayeon Kim and Joon-Sung Joh

    BMC Infectious Diseases 2017 17:498

    Published on: 14 July 2017

  9. Research article

    Early warning signal for dengue outbreaks and identification of high risk areas for dengue fever in Colombia using climate and non-climate datasets

    Dengue has been prevalent in Colombia with high risk of outbreaks in various locations. While the prediction of dengue epidemics will bring significant benefits to the society, accurate forecasts have been a c...

    Jung-Seok Lee, Mabel Carabali, Jacqueline K. Lim, Victor M. Herrera, Il-Yeon Park, Luis Villar and Andrew Farlow

    BMC Infectious Diseases 2017 17:480

    Published on: 10 July 2017

  10. Research article

    SOFIA®RSV: prospective laboratory evaluation and implementation of a rapid diagnostic test in a pediatric emergency ward

    Respiratory syncytial virus (RSV) is responsible for severe respiratory infections and higher costs in medical care. The two aims of this work were to assess the performances of SOFIA®RSV tests in “real-life-labo...

    Léa C. Tran, Céline Tournus, Julia Dina, Rémy Morello, Jacques Brouard and Astrid Vabret

    BMC Infectious Diseases 2017 17:452

    Published on: 26 June 2017

  11. Research article

    Assessing changes in knowledge, attitude and practices on dengue diagnosis and management among primary care physicians after the largest dengue epidemic in Singapore

    Dengue results in high morbidity and mortality globally. The knowledge, attitude and practices (KAP) of dengue management, including diagnosis, among primary care physicians (PCPs) are important to reduce deng...

    Junxiong Pang, Zoe Jane-Lara Hildon, Tun Linn Thein, Jing Jin and Yee Sin Leo

    BMC Infectious Diseases 2017 17:428

    Published on: 15 June 2017

  12. Case report

    Case report: microcephaly associated with Zika virus infection, Colombia

    Recently there has been a large outbreak of Zika virus infections in Colombia, South America. The epidemic began in September 2015 and continued to April 2017, for the total number of Zika cases reported of 10...

    Salim Mattar, Carolina Ojeda, Janna Arboleda, German Arrieta, Irene Bosch, Ingrid Botia, Nelson Alvis-Guzman, Carlos Perez-Yepes, Lee Gerhke and German Montero

    BMC Infectious Diseases 2017 17:423

    Published on: 13 June 2017

  13. Research article

    Dengue type 4 in Rio de Janeiro, Brazil: case characterization following its introduction in an endemic region

    Due to the populations’ susceptibility, DENV-4 introduction in 2010 led to the occurrence of explosive epidemics in the following years in Brazil. In 2011, DENV-4 was identified in Rio de Janeiro (RJ) and it w...

    Manoela Heringer, Thiara Manuele A Souza, Monique da Rocha Q Lima, Priscila Conrado G Nunes, Nieli Rodrigues da C Faria, Fernanda de Bruycker-Nogueira, Thaís Chouin-Carneiro, Rita Maria R Nogueira and Flavia Barreto dos Santos

    BMC Infectious Diseases 2017 17:410

    Published on: 9 June 2017

  14. Research article

    Genetic variants of MICB and PLCE1 and associations with the laboratory features of dengue

    A previous genome-wide association study identified 2 susceptibility loci for severe dengue at MICB rs3132468 and PLCE1 rs3740360 and further work showed these mutations to be also associated with less severe cli...

    James Whitehorn, Duong Thi Hue Kien, Nguyen Than Ha Quyen, Bridget Wills, Nguyen Van Vinh Chau, Dong Thi Hoai Tam, Nguyen Minh Tuan, Thomas Jaenisch, Martin Hibberd, Chiea Chuen Khor and Cameron P. Simmons

    BMC Infectious Diseases 2017 17:412

    Published on: 9 June 2017

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