Viral diseases

Section edited by Jodie McVernon and Julian Tang

This section aims to publish studies looking at all aspects of of the prevention, diagnosis and management of viral diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. HIV, HIV-associated infections and sexually transmitted diseases are considered in separate sections.

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  1. Research article

    Prevalence of congenital cytomegalovirus infection in symptomatic newborns under 3 weeks in Tehran, Iran

    Cytomegalovirus (CMV) is a common cause of congenital infection worldwide and infants with symptomatic congenital CMV (cCMV) infection are at significantly increased risk of developing adverse long-term outcom...

    Mina Ebrahimi-Rad, Talayeh Seyed Shakeri, Fariba Shirvani, Kiana Shahrokhi and Nader Shahrokhi

    BMC Infectious Diseases 2017 17:688

    Published on: 18 October 2017

  2. Research article

    Cost-utility analysis of Palivizumab for Respiratory Syncytial Virus infection prophylaxis in preterm infants: update based on the clinical evidence in Spain

    This study aimed at estimating the efficiency of palivizumab in the prevention of Respiratory Syncytial Virus (RSV) infection and its sequelae in preterm infants (32day 1-35day 0weeks of gestational age –wGA-) in...

    M. Sanchez-Luna, R. Burgos-Pol, I. Oyagüez, J. Figueras-Aloy, M. Sánchez-Solís, F. Martinón-Torres and X. Carbonell-Estrany

    BMC Infectious Diseases 2017 17:687

    Published on: 17 October 2017

  3. Research article

    A retrospective cohort study to predict severe dengue in Honduran patients

    An important challenge in the identification of dengue is how to predict which patients will go on to experience severe illness, which is typically characterized by fever, thrombocytopenia, haemorrhagic manife...

    Eduardo Fernández, Marek Smieja, Stephen D. Walter and Mark Loeb

    BMC Infectious Diseases 2017 17:676

    Published on: 11 October 2017

  4. Research article

    Community-based surveillance of norovirus disease: a systematic review

    Norovirus is a common cause of infectious gastrointestinal disease. Despite the increased ability to detect norovirus in affected people, the number of reported cases and outbreaks in the community is still su...

    Thomas Inns, John Harris, Roberto Vivancos, Miren Iturriza-Gomara and Sarah O’Brien

    BMC Infectious Diseases 2017 17:657

    Published on: 29 September 2017

  5. Research article

    B-type brain natriuretic peptide as a measure of the severity of hand-foot-mouth disease: a case-control study

    Hand-foot-mouth disease (HFMD) is an acute infectious disease caused by enteroviruses, and HFMD complicated by cardiopulmonary failure has a high mortality. B type natriuretic peptide (BNP) is widely applied i...

    AYuan Zhang, Lin Yang, Pengfei Guo, Shaojun Li, Xiaoxiao Ao, Feng Xu and Liping Tan

    BMC Infectious Diseases 2017 17:651

    Published on: 29 September 2017

  6. Research article

    Possible explanations for why some countries were harder hit by the pandemic influenza virus in 2009 – a global mortality impact modeling study

    A global pandemic mortality study found prominent regional mortality variations in 2009 for Influenza A(H1N1)pdm09. Our study attempts to identify factors that explain why the pandemic mortality burden was hig...

    Kathleen F. Morales, John Paget and Peter Spreeuwenberg

    BMC Infectious Diseases 2017 17:642

    Published on: 25 September 2017

  7. Research article

    Spatio-temporal clustering analysis and its determinants of hand, foot and mouth disease in Hunan, China, 2009–2015

    Hand, foot and mouth disease (HFMD) is one of the highest reported infectious diseases with several outbreaks across the world. This study aimed at describing epidemiological characteristics, investigating spa...

    Xinrui Wu, Shixiong Hu, Abuaku Benjamin Kwaku, Qi Li, Kaiwei Luo, Ying Zhou and Hongzhuan Tan

    BMC Infectious Diseases 2017 17:645

    Published on: 25 September 2017

  8. Research article

    Who’s holding the baby? A prospective diary study of the contact patterns of mothers with an infant

    Models of infectious disease are increasingly utilising empirical contact data to quantify the number of potentially infectious contacts between age groups. While a growing body of data is being collected on c...

    Patricia Therese Campbell, Jodie McVernon, Niraj Shrestha, Paula M. Nathan and Nicholas Geard

    BMC Infectious Diseases 2017 17:634

    Published on: 20 September 2017

  9. Research article

    Future complications of chronic hepatitis C in a low-risk area: projections from the hepatitis c study in Northern Norway

    Hepatitis C (HCV) infection causes an asymptomatic chronic hepatitis in most affected individuals, which often remains undetected until cirrhosis and cirrhosis-related complications occur. Screening of high-ri...

    H. Kileng, L. Bernfort, T. Gutteberg, O.S. Moen, M.G. Kristiansen, E.J. Paulssen, L.K. Berg, J. Florholmen and R. Goll

    BMC Infectious Diseases 2017 17:624

    Published on: 16 September 2017

  10. Research article

    Exposure rate of VZV among women attending antenatal care clinic in Sri Lanka - a cross sectional study

    Varicella or chickenpox was not a notifiable disease until 2005 in Sri Lanka and only a few studies have been conducted on the epidemiology of VZV infection in the country. The anti­VZV IgG sero-prevalence amo...

    Saluwadana Walawwe Pavithra Lakmini Daulagala, Faseeha Noordeen, Mohamed Mukthar Fathina Fara, Chathura Rathnayake and Kapila Gunawardana

    BMC Infectious Diseases 2017 17:625

    Published on: 16 September 2017

  11. Research Article

    Lessons from a decade of individual-based models for infectious disease transmission: a systematic review (2006-2015)

    Individual-based models (IBMs) are useful to simulate events subject to stochasticity and/or heterogeneity, and have become well established to model the potential (re)emergence of pathogens (e.g., pandemic in...

    Lander Willem, Frederik Verelst, Joke Bilcke, Niel Hens and Philippe Beutels

    BMC Infectious Diseases 2017 17:612

    Published on: 11 September 2017

  12. Research article

    The predictors of 3- and 30-day mortality in 660 MERS-CoV patients

    The mortality rate of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) patients is a major challenge in all healthcare systems worldwide. Because the MERS-CoV risk-standardized mortality rates are curre...

    Anwar E. Ahmed

    BMC Infectious Diseases 2017 17:615

    Published on: 11 September 2017

  13. Research article

    Incidence of human rabies and characterization of rabies virus nucleoprotein gene in dogs in Fujian Province, Southeast China, 2002–2012

    Rabies is a global fatal infectious viral disease that is characterized by a high mortality after onset of clinical symptoms. Recently, there has been an increase in the incidence of rabies in China. The aim o...

    Jian-Ming Zhang, Zhi-Shan Zhang, Yan-Qin Deng, Shou-Li Wu, Wei Wang and Yan-Sheng Yan

    BMC Infectious Diseases 2017 17:599

    Published on: 30 August 2017

  14. Research article

    Precisão e confiabilidade de um teste imuno-cromatográfico rápido NS1 para diagnóstico DENV-1 no ponto de atendimento e no laboratório

    Rapid immunochromatographic tests (ICT) for dengue non-structural protein 1 (NS1) have shown good performance for diagnosing acute-phase dengue in serum in laboratory settings, but rarely have been assessed in...

    Verónica Elizabeth Mata, Sonia Regina Lambert Passos, Yara Hahr Marques Hökerberg, Guilherme Miguéis Berardinelli, Maria Angelica Borges dos Santos, Levy Vilas Boas Fukuoka, Anna Carolina Fontoura Seixas Rangel Maciel, Cintia Damasceno dos Santos Rodrigues, Aline da Silva Santos and Raquel de Vasconcellos Carvalhaes de Oliveira

    BMC Infectious Diseases 2017 17:594

    Published on: 29 August 2017

  15. Research article

    The contribution of respiratory pathogens to fatal and non-fatal respiratory hospitalizations: a pilot study of Taqman Array Cards (TAC) in Kenya

    Respiratory diseases cause substantial morbidity and mortality worldwide, with sub-Saharan Africa bearing the greatest burden. Identifying etiologies of respiratory disease is important to inform cost effectiv...

    Henry N. Njuguna, Sandra S. Chaves, Gideon O. Emukule, Bryan Nyawanda, Victor Omballa, Bonventure Juma, Clayton O. Onyango, Joshua A. Mott and Barry Fields

    BMC Infectious Diseases 2017 17:591

    Published on: 25 August 2017

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