Viral diseases

Section edited by Jodie McVernon and Julian Tang

This section aims to publish studies looking at all aspects of of the prevention, diagnosis and management of viral diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. HIV, HIV-associated infections and sexually transmitted diseases are considered in separate sections.

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  1. Research article

    Clinical manifestations of severe enterovirus 71 infection and early assessment in a Southern China population

    Enterovirus 71 (EV-A71) shows a potential of rapid death, but the natural history of the infection is poorly known. This study aimed to examine the natural history of EV-A71 infection.

    Si-da Yang, Pei-qing Li, Yi-min Li, Wei Li, Wen-ying Lai, Cui-ping Zhu, Jian-ping Tao, Li Deng, Hong-sheng Liu, Wen-cheng Ma, Jia-ming Lu, Yan Hong, Yu-ting Liang, Jun Shen, Dan-dan Hu, Yuan-yuan Gao…

    BMC Infectious Diseases 2017 17:153

    Published on: 17 February 2017

  2. Research article

    Effective inhibition of MERS-CoV infection by resveratrol

    Middle East Respiratory Syndrome coronavirus (MERS-CoV) is an emerging viral pathogen that causes severe morbidity and mortality. Up to date, there is no approved or licensed vaccine or antiviral medicines can...

    Shih-Chao Lin, Chi-Tang Ho, Wen-Ho Chuo, Shiming Li, Tony T. Wang and Chi-Chen Lin

    BMC Infectious Diseases 2017 17:144

    Published on: 13 February 2017

  3. Research article

    A population-based study of chronic hepatitis C in immigrants and non-immigrants in Quebec, Canada

    Immigrants originating from intermediate and high HCV prevalence countries may be at increased risk of exposure to hepatitis C infection (HCV) in their countries of origin, however they are not routinely scree...

    Christina Greenaway, Laurent Azoulay, Robert Allard, Joseph Cox, Viet Anh Tran, Claire Nour Abou Chakra, Russ Steele and Marina Klein

    BMC Infectious Diseases 2017 17:140

    Published on: 13 February 2017

  4. Research article

    Viral aetiology of bronchiolitis in hospitalised children in Qatar

    Bronchiolitis is considered one of the earliest and most common causes of hospitalisation in young children. Development of molecular technologies allowed a better understanding of bronchiolitis aetiology. Res...

    Ibrahim Janahi, Anas Abdulkayoum, Fawziya Almeshwesh, Mohamed Alkuwari, Ahmed Al hammadi and Marwah Alameri

    BMC Infectious Diseases 2017 17:139

    Published on: 13 February 2017

  5. Research article

    Study on age-dependent pre-existing 2009 pandemic influenza virus T and B cell responses from Chinese population

    The outbreak of the 2009 H1N1 influenza pandemic (H1N1pdm) affected thousands of people in Mexico and the United States, and spread rapidly throughout the world from April 2009 to July 2010. To explore the age...

    Jin Lv, Zhen-Yong Ren, Ying-Ying Zhang, Yun-E Liu, Jun Gao, Kun Yao, Dan Feng, Zhen-Yuan Li, Xin Feng, Yun-Xi Liu and Na Jia

    BMC Infectious Diseases 2017 17:136

    Published on: 10 February 2017

  6. Correspondence

    Beyond Ebola treatment units: severe infection temporary treatment units as an essential element of Ebola case management during an outbreak

    In the course of the Ebola outbreak in West Africa that was witnessed since early 2014, the response mechanisms showed deficits in terms of timeliness, volume and adequacy. The authors were deployed in the Ebo...

    Christian Janke, Katrin Moira Heim, Florian Steiner, Moses Massaquoi, Miatta Zenabu Gbanya, Claudia Frey and Guenter Froeschl

    BMC Infectious Diseases 2017 17:124

    Published on: 6 February 2017

  7. Study protocol

    Molecular point-of-care testing for respiratory viruses versus routine clinical care in adults with acute respiratory illness presenting to secondary care: a pragmatic randomised controlled trial protocol (ResPOC)

    Respiratory viruses are associated with a huge socio-economic burden and are responsible for a large proportion of acute respiratory illness in hospitalised adults. Laboratory PCR is accurate but takes at leas...

    Nathan J. Brendish, Ahalya K. Malachira and Tristan W. Clark

    BMC Infectious Diseases 2017 17:128

    Published on: 6 February 2017

  8. Research article

    Using a community based survey of healthcare seeking behavior to estimate the actual magnitude of influenza among adults in Beijing during 2013-2014 season

    Due to a lack of survey of health care seeking behavior for influenza, the actual magnitude of influenza in Beijing of China has not been well described.

    Xiaoli Wang, Shuangsheng Wu, Peng Yang, Hongjun Li, Yanhui Chu, Yaqing Tang, Weiyu Hua, Haiyan Zhang, Chao Li and Quanyi Wang

    BMC Infectious Diseases 2017 17:120

    Published on: 3 February 2017

  9. Research article

    Norovirus infections in young children in Lusaka Province, Zambia: clinical characteristics and molecular epidemiology

    The burden, clinical features, and molecular epidemiology of norovirus infection in young children in southern Africa are not well defined.

    Leigh M. Howard, Innocent Mwape, Mpanji Siwingwa, Michelo Simuyandi, M. Brad Guffey, Jeffrey S. A. Stringer, Benjamin H. Chi, Kathryn M. Edwards and Roma Chilengi

    BMC Infectious Diseases 2017 17:92

    Published on: 23 January 2017

  10. Research article

    Epidemiology of laboratory confirmed measles virus cases in the southern nations of Ethiopia, 2007–2014

    In Ethiopia, measles case-based surveillance was introduced in 2004 as one strategy for measles control by laboratory confirmation of suspected cases. In this article, epidemiological distribution of laborator...

    Mekonen Getahun, Berhane Beyene, Ayesheshem Ademe, Birke Teshome, Mesfin Tefera, Aklog Afework, Yoseph HaileMariam, Esete Assefa, Yonas Hailegiorgis and Anjelo Asha

    BMC Infectious Diseases 2017 17:87

    Published on: 19 January 2017

  11. Research article

    Thromboelastometry analysis of thrombocytopenic dengue patients: a cross-sectional study

    Dengue virus infection (DVI) is a prevalent and potentially fatal viral disease associated with coagulopathy. So far, the coagulation profile of DVI patients with thrombocytopenia has not been assessed through...

    Felipe Maia de Toledo Piza, Thiago Domingos Corrêa, Alexandre Rodrigues Marra, João Carlos Campos Guerra, Roseny dos Reis Rodrigues, Andrea Aparecida Rocco Villarinho, Valdir Fernandes de Aranda, Sandra Christina Pereira Lima Shiramizo, Maria Roza de Jesus de Lima, Esper Georges Kallas and Alexandre Biasi Cavalcanti

    BMC Infectious Diseases 2017 17:89

    Published on: 19 January 2017

  12. Research article

    Influenza epidemic surveillance and prediction based on electronic health record data from an out-of-hours general practitioner cooperative: model development and validation on 2003–2015 data

    Annual influenza epidemics significantly burden health care. Anticipating them allows for timely preparation. The Scientific Institute of Public Health in Belgium (WIV-ISP) monitors the incidence of influenza ...

    Barbara Michiels, Van Kinh Nguyen, Samuel Coenen, Philippe Ryckebosch, Nathalie Bossuyt and Niel Hens

    BMC Infectious Diseases 2017 17:84

    Published on: 18 January 2017

  13. Research article

    Randomized, double-blind, placebo-controlled clinical trial to assess the safety and effectiveness of a novel dual-action oral topical formulation against upper respiratory infections

    Current prevention options for upper respiratory infections (URIs) are not optimal. We conducted a randomized, double-blinded, placebo-controlled pilot clinical trial to evaluate the safety and efficacy of ARM...

    Pranab K. Mukherjee, Frank Esper, Ken Buchheit, Karen Arters, Ina Adkins, Mahmoud A. Ghannoum and Robert A. Salata

    BMC Infectious Diseases 2017 17:74

    Published on: 14 January 2017

  14. Research article

    Application of the analytic hierarchy approach to the risk assessment of Zika virus disease transmission in Guangdong Province, China

    An international spread of Zika virus (ZIKV) infection has attracted global attention in 2015. The infection also affected Guangdong province, which is located in southern China. Multiple factors, including fr...

    Xing Li, Tao Liu, Lifeng Lin, Tie Song, Xiaolong Du, Hualiang Lin, Jianpeng Xiao, Jianfeng He, Liping Liu, Guanghu Zhu, Weilin Zeng, Lingchuan Guo, Zheng Cao, Wenjun Ma and Yonghui Zhang

    BMC Infectious Diseases 2017 17:65

    Published on: 13 January 2017

  15. Research article

    Evaluation of the point-of-care Becton Dickinson Veritor™ Rapid influenza diagnostic test in Kenya, 2013–2014

    We evaluated the performance of the Becton Dickinson Veritor™ System Flu A + B rapid influenza diagnostic test (RIDT) to detect influenza viruses in respiratory specimens from patients enrolled at five surveil...

    Linus K. Ndegwa, Gideon Emukule, Timothy M. Uyeki, Eunice Mailu, Sandra S. Chaves, Marc-Alain Widdowson, Bandika V. Lewa, Francis K. Muiruri, Peter Omoth, Barry Fields and Joshua A. Mott

    BMC Infectious Diseases 2017 17:60

    Published on: 11 January 2017

  16. Research article

    Single- and multiple viral respiratory infections in children: disease and management cannot be related to a specific pathogen

    The number of viral pathogens associated with pediatric acute respiratory tract infection (ARI) has grown since the introduction of reverse transcription real-time polymerase chain reaction (RT-PCR) assays. Mu...

    Jérôme O. Wishaupt, Tjeerd van der Ploeg, Ronald de Groot, Florens G. A. Versteegh and Nico G. Hartwig

    BMC Infectious Diseases 2017 17:62

    Published on: 11 January 2017

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