Viral diseases

Section edited by Jodie McVernon and Julian Tang

This section aims to publish studies looking at all aspects of of the prevention, diagnosis and management of viral diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. HIV, HIV-associated infections and sexually transmitted diseases are considered in separate sections.

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  1. Case report

    Lessons learned by surveillance during the tail-end of the Ebola outbreak in Guinea, June-October 2015: a case series

    By the end of the 2013–2016 West African Ebola Virus Disease (EVD) outbreaks, a total of 3814 cases (probable and confirmed) and 2544 deaths were reported in Guinea. Clearly, surveillance activities aiming at ...

    Mory Keïta, Fatoumata Conté, Boubacar Diallo, Dieudonné Lufwa, Jacques Katomba, René Snacken, Raymond Pallawo, Aminata Tolno, Amadou Bailo Diallo, Mamadou Harouna Djingarey and Lorenzo Subissi

    BMC Infectious Diseases 2017 17:304

    Published on: 24 April 2017

  2. Research article

    Viral aetiologies of acute encephalitis in a hospital-based South Asian population

    The aetiological spectrum of acute encephalitis shows inter- and intra-geographical variations. We aimed to identify the viruses that cause infectious encephalitis in Sri Lanka, which represents a South Asian ...

    Janarthani Lohitharajah, Neelika Malavige, Carukshi Arambepola, Jithangi Wanigasinghe, Ranjanie Gamage, Padma Gunaratne, Pyara Ratnayake and Thashi Chang

    BMC Infectious Diseases 2017 17:303

    Published on: 24 April 2017

  3. Research article

    Point of sampling detection of Zika virus within a multiplexed kit capable of detecting dengue and chikungunya

    Zika, dengue, and chikungunya are three mosquito-borne viruses having overlapping transmission vectors. They cause diseases having similar symptoms in human patients, but requiring different immediate manageme...

    Ozlem Yaren, Barry W. Alto, Priyanka V. Gangodkar, Shatakshi R. Ranade, Kunal N. Patil, Kevin M. Bradley, Zunyi Yang, Nikhil Phadke and Steven A. Benner

    BMC Infectious Diseases 2017 17:293

    Published on: 20 April 2017

  4. Research article

    Rubella Seroprevalence and real-time PCR detection of RUBV among Congolese pregnant women

    Rubella is an acute infectious disease caused by Rubella virus (RUBV). RUBV remains an important pathogen worldwide, causing approximately 100 000 cases of congenital rubella syndrome (CRS) every year; and the...

    Josue Zanga, Makola Kennedy Mbanzulu, Arnold-Freddy Kabasele, Nlandu Roger Ngatu and Dimosi Roger Wumba

    BMC Infectious Diseases 2017 17:250

    Published on: 5 April 2017

  5. Research article

    Spatial, temporal and spatio-temporal clusters of measles incidence at the county level in Guangxi, China during 2004–2014: flexibly shaped scan statistics

    Outbreaks of measles re-emerged in Guangxi province during 2013–2014, where measles again became a major public health concern. A better understanding of the patterns of measles cases would help in identifying...

    Xianyan Tang, Alan Geater, Edward McNeil, Qiuyun Deng, Aihu Dong and Ge Zhong

    BMC Infectious Diseases 2017 17:243

    Published on: 4 April 2017

  6. Research article

    Upper airway viruses and bacteria in urban Aboriginal and Torres Strait Islander children in Brisbane, Australia: a cross-sectional study

    Respiratory morbidity in Australian Indigenous children is higher than their non-Indigenous counterparts, irrespective of urban or remote residence. There are limited studies addressing acute respiratory illne...

    Kerry-Ann F. O’Grady, Kerry K. Hall, Theo P. Sloots, Jennie Anderson and Anne B. Chang

    BMC Infectious Diseases 2017 17:245

    Published on: 4 April 2017

  7. Research article

    Determination of the Cell Permissiveness Spectrum, Mode of RNA Replication, and RNA-Protein Interaction of Zika Virus

    Two lineages of Zika virus (ZIKV) have been classified according to the phylogenetic analysis: African and Asian lineages. It is unclear whether differences exist between the two strains in host cell permissiv...

    Wangheng Hou, Najealicka Armstrong, Lilian Akello Obwolo, Michael Thomas, Xiaowu Pang, Kevin S. Jones and Qiyi Tang

    BMC Infectious Diseases 2017 17:239

    Published on: 31 March 2017

  8. Study protocol

    Influenza and respiratory syncytial virus in infants study (IRIS) of hospitalized and non-ill infants aged <1 year in four countries: study design and methods

    This multi-country prospective study of infants aged <1 year aims to assess the frequency of influenza virus and respiratory syncytial virus (RSV) infections associated with hospitalizations, to describe clini...

    Mark G. Thompson, Danielle R. Hunt, Ali K. Arbaji, Artan Simaku, Veronica L. Tallo, Holly M. Biggs, Carolyn Kulb, Aubree Gordon, Ilham Abu Khader, Silvia Bino, Marilla G. Lucero, Eduardo Azziz-Baumgartner, Pat Shifflett, Felix Sanchez, Basima I. Marar, Ilirjana Bakalli…

    BMC Infectious Diseases 2017 17:222

    Published on: 22 March 2017

  9. Research article

    Cytomegalovirus, Epstein-Barr virus and varicella zoster virus infection in the first two years of life: a cohort study in Bradford, UK

    Cytomegalovirus (CMV), Epstein Barr virus (EBV) and varicella-zoster virus (VZV) are common herpesviruses frequently acquired in childhood, which establish persistent, latent infection and are likely to impact...

    Lucy Pembrey, Dagmar Waiblinger, Paul Griffiths, Mauli Patel, Rafaq Azad and John Wright

    BMC Infectious Diseases 2017 17:220

    Published on: 21 March 2017

  10. Research article

    Seasonal patterns of dengue fever and associated climate factors in 4 provinces in Vietnam from 1994 to 2013

    In Vietnam, dengue fever (DF) is still a leading cause of hospitalization. The main objective of this study was to evaluate the seasonality and association with climate factors (temperature and precipitation) ...

    Hu Suk Lee, Hung Nguyen-Viet, Vu Sinh Nam, Mihye Lee, Sungho Won, Phuc Pham Duc and Delia Grace

    BMC Infectious Diseases 2017 17:218

    Published on: 20 March 2017

  11. Research article

    Antiviral activity of PHA767491 against human herpes simplex virus in vitro and in vivo

    Herpes simplex virus (HSV) is a common human pathogen that causes a variety of diseases, including oral-labial, genital lesions and life-threatening encephalitis. The antiviral nucleoside analogues such as acy...

    Jue Hou, Zili Zhang, Qiang Huang, Jun Yan, Xiaohu Zhang, Xiaoliang Yu, Guihua Tan, Chunfu Zheng, Feng Xu and Sudan He

    BMC Infectious Diseases 2017 17:217

    Published on: 20 March 2017

  12. Research article

    Imported arboviral infections in Italy, July 2014-October 2015: a National Reference Laboratory report

    Imported cases of infections due to Dengue (DENV) and Chikungunya (CHIKV) viruses and, more recently, Zika virus (ZIKV) are commonly reported among travelers returning from endemic regions. In areas where pote...

    Claudia Fortuna, Maria Elena Remoli, Caterina Rizzo, Eleonora Benedetti, Cristiano Fiorentini, Antonino Bella, Claudio Argentini, Francesca Farchi, Concetta Castilletti, Maria Rosaria Capobianchi, Lorenzo Zammarchi, Alessandro Bartoloni, Nadia Zanchetta, Maria Rita Gismondo, Luca Ceccherini Nelli, Giustina Vitale…

    BMC Infectious Diseases 2017 17:216

    Published on: 16 March 2017

  13. Review

    Looking back to move forward: a twenty-year audit of herpes zoster in Asia-Pacific

    Herpes zoster (HZ) is a prevalent viral disease that inflicts substantial morbidity and associated healthcare and socioeconomic burdens. Current treatments are not fully effective, especially among the most vu...

    Liang-Kung Chen, Hidenori Arai, Liang-Yu Chen, Ming-Yueh Chou, Samsuridjal Djauzi, Birong Dong, Taro Kojima, Ki Tae Kwon, Hoe Nam Leong, Edward M. F. Leung, Chih-Kuang Liang, Xiaohong Liu, Dilip Mathai, Jiun Yit Pan, Li-Ning Peng, Eduardo Rommel S. Poblete…

    BMC Infectious Diseases 2017 17:213

    Published on: 15 March 2017

  14. Research article

    Increased sensitivity of NS1 ELISA by heat dissociation in acute dengue 4 cases

    Dengue is an acute febrile illness considered the major arboviral disease in terms of morbidity, mortality, economic impact and dissemination worldwide. Brazil accounts for the highest notification rate, with ...

    Sibelle Nogueira Buonora, Flavia Barreto dos Santos, Regina Paiva Daumas, Sonia Regina Lambert Passos, Manoela Heringer da Silva, Monique Rocha de Lima and Rita Maria Ribeiro Nogueira

    BMC Infectious Diseases 2017 17:204

    Published on: 11 March 2017

  15. Technical advance

    ICARES: a real-time automated detection tool for clusters of infectious diseases in the Netherlands

    Clusters of infectious diseases are frequently detected late. Real-time, detailed information about an evolving cluster and possible associated conditions is essential for local policy makers, travelers planni...

    Geert H. Groeneveld, Anton Dalhuijsen, Chakib Kara-Zaïtri, Bob Hamilton, Margot W. de Waal, Jaap T. van Dissel and Jim E. van Steenbergen

    BMC Infectious Diseases 2017 17:201

    Published on: 9 March 2017

  16. Research article

    Clinical features of community acquired adenovirus pneumonia during the 2011 community outbreak in Southern Taiwan: role of host immune response

    Human adenovirus 7 (HAdV-7) was responsible for a significant number of fatalities during the 2011 community outbreak in Taiwan. The mechanisms underlying the pathogenesis of severe adenovirus infections in no...

    Ching-Fen Shen, Shih-Min Wang, Tzong-Shiann Ho and Ching-Chuan Liu

    BMC Infectious Diseases 2017 17:196

    Published on: 7 March 2017

  17. Research article

    A meta-analysis of stroke risk following herpes zoster infection

    The incidence of herpes zoster (HZ) is increasing and poses a significant health concern to aging populations. Several studies suggest an increased risk of stroke following zoster infection, but the results ar...

    Fawziah Marra, Jeremy Ruckenstein and Kathryn Richardson

    BMC Infectious Diseases 2017 17:198

    Published on: 7 March 2017

  18. Research article

    Clinical manifestations of severe enterovirus 71 infection and early assessment in a Southern China population

    Enterovirus 71 (EV-A71) shows a potential of rapid death, but the natural history of the infection is poorly known. This study aimed to examine the natural history of EV-A71 infection.

    Si-da Yang, Pei-qing Li, Yi-min Li, Wei Li, Wen-ying Lai, Cui-ping Zhu, Jian-ping Tao, Li Deng, Hong-sheng Liu, Wen-cheng Ma, Jia-ming Lu, Yan Hong, Yu-ting Liang, Jun Shen, Dan-dan Hu, Yuan-yuan Gao…

    BMC Infectious Diseases 2017 17:153

    Published on: 17 February 2017

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