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Vaccines

This section aims to publish studies looking at the development and application of vaccines, including efficacy, safety, population coverage and barriers to vaccination.

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  1. Tetanus-reduced dose diphtheria-acellular pertussis (Tdap) vaccination during adolescence was introduced in response to the resurgence of pertussis in various countries. A new Tdap vaccine was manufactured in ...

    Authors: Hyo Jin Kwon, Seung Beom Han, Bo Ram Kim, Kyu Ri Kang, Dong Ho Huh, Gi Sub Choi, Dong Ho Ahn and Jin Han Kang

    Citation: BMC Infectious Diseases 2017 17:247

    Content type: Research article

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  2. Current influenza vaccines, based on antibodies against surface antigens, are unable to provide protection against newly emerging virus strains which differ from the vaccine strains. Therefore the population h...

    Authors: Eva van Doorn, Olga Pleguezuelos, Heng Liu, Ana Fernandez, Robin Bannister, Gregory Stoloff, Fredrik Oftung, Stephen Norley, Anke Huckriede, Henderik W. Frijlink and Eelko Hak

    Citation: BMC Infectious Diseases 2017 17:241

    Content type: Study protocol

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  3. Vaccination against seasonal influenza strains is recommended for “high risk” patient groups such as infants, elderly and those with respiratory or circulatory diseases. However, efficacy of the trivalent infl...

    Authors: M. D Heath, N. J. Swan, A. C. Marriott, N. J. Silman, B. Hallis, C. Prevosto, K. E. Gooch and M. A. Skinner

    Citation: BMC Infectious Diseases 2017 17:232

    Content type: Research article

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  4. To support the evaluation of the 2010-15 National Plan for Measles and Congenital Rubella Elimination, the authors designed and performed a serosurveillance survey to verify the immunity/susceptibility rate ag...

    Authors: Gallone Maria Serena, Gallone Maria Filomena, Larocca Angela Maria Vittoria, Germinario Cinzia and Tafuri Silvio

    Citation: BMC Infectious Diseases 2017 17:199

    Content type: Research article

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    The Erratum to this article has been published in BMC Infectious Diseases 2017 17:630

  6. Fasciolosis remains a significant food-borne trematode disease causing high morbidity around the world and affecting grazing animals and humans. A deeper understanding concerning the molecular mechanisms by wh...

    Authors: Jose Rojas-Caraballo, Julio López-Abán, Darwin Andrés Moreno-Pérez, Belén Vicente, Pedro Fernández-Soto, Esther del Olmo, Manuel Alfonso Patarroyo and Antonio Muro

    Citation: BMC Infectious Diseases 2017 17:94

    Content type: Research article

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  7. Mumps emerged among highly vaccinated populations in the Netherlands. This offered a unique opportunity to study mumps virus transmission. In particular the extent to which asymptomatic infections in vaccinate...

    Authors: Susan Hahné, Tessa Schurink, Jacco Wallinga, Jeroen Kerkhof, Marianne van der Sande, Rob van Binnendijk and Hester de Melker

    Citation: BMC Infectious Diseases 2017 17:56

    Content type: Research article

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  9. A widely prevalent disease, toxoplasmosis poses serious health threats to both humans and animals; therefore, development of an ideal DNA vaccine against Toxoplasma gondii is needed eagerly. The purpose of the pr...

    Authors: Pengxia Song, Shenyi He, Aihua Zhou, Gang Lv, Jingjing Guo, Jian Zhou, Yali Han, Huaiyu Zhou, Zhen Hao and Hua Cong

    Citation: BMC Infectious Diseases 2017 17:19

    Content type: Research article

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  10. In Sri Lanka pertussis continues to circulate in the community and cases among adolescents and adults have been reported despite 95% coverage of the four dose pertussis vaccination during early childhood. Wani...

    Authors: Shamithra Sigera, Jennifer Perera, Jeyanthakumar Rasarathinam, Dulani Samaranayake and Dileepa Ediriweera

    Citation: BMC Infectious Diseases 2016 16:729

    Content type: Research article

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  11. In order to control the spread of rubella and reduce the risk for congenital rubella syndrome, an additional rubella vaccination program was set up for all secondary school students since 2008 in Zhejiang, China.

    Authors: Hanqing He, Rui Yan, Xuewen Tang, Yang Zhou, Xuan Deng and Shuyun Xie

    Citation: BMC Infectious Diseases 2016 16:723

    Content type: Research article

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  12. In many industrialized countries routine vaccination with the 23-valent pneumococcal polysaccharide vaccine (PPSV-23) is recommended to prevent pneumococcal disease in the elderly. However, vaccine-induced imm...

    Authors: Cornelius Remschmidt, Thomas Harder, Ole Wichmann, Christian Bogdan and Gerhard Falkenhorst

    Citation: BMC Infectious Diseases 2016 16:711

    Content type: Research article

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  13. Rotavirus infection causes considerable disease burden of acute gastroenteritis (AGE) hospitalization and death among children less than 5 years in China. Although two rotavirus vaccines (Rotarix and RotaTeq) ...

    Authors: Shuhui Cui, Ruoyan Gai Tobe, Xiuting Mo, Xiaoyan Liu, Lingzhong Xu and Shixue Li

    Citation: BMC Infectious Diseases 2016 16:677

    Content type: Research article

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    The Correction to this article has been published in BMC Infectious Diseases 2018 18:487

  14. The demographic composition and the frequency and nature of social contacts may affect the spread of influenza virus in a population, resulting in distinct age-dependent immunity patterns. As demography and so...

    Authors: Ruprecht Schmidt-Ott, Markus Schwehm and Martin Eichner

    Citation: BMC Infectious Diseases 2016 16:646

    Content type: Research article

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  15. An evidence-based, step-by-step guide, the 4 Pillars™ Practice Transformation Program, was the foundation of an intervention to increase adult immunizations in primary care and was tested in a randomized contr...

    Authors: Chyongchiou J. Lin, Mary Patricia Nowalk, Valory N. Pavlik, Anthony E. Brown, Song Zhang, Jonathan M. Raviotta, Krissy K. Moehling, Mary Hawk, Edmund M. Ricci, Donald B. Middleton, Suchita Patel, Jeannette E. South-Paul and Richard K. Zimmerman

    Citation: BMC Infectious Diseases 2016 16:623

    Content type: Research article

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  16. Dengue virus (DENV) and Japanese encephalitis virus (JEV) belong to the genus Flavivirus, and infection with a virus within this genus induces antibodies that are cross-reactive to other flaviviruses. Particularl...

    Authors: Yuka Saito, Meng Ling Moi, Nozomi Takeshita, Chang-Kweng Lim, Hajime Shiba, Kuniaki Hosono, Masayuki Saijo, Ichiro Kurane and Tomohiko Takasaki

    Citation: BMC Infectious Diseases 2016 16:578

    Content type: Research article

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  17. Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are responsible for a significant disease burden amongst Māori and Pacific populations in New Zealand (NZ). However, contemporary data are lacking ...

    Authors: Deborah A Williamson, Pierre R Smeesters, Andrew C Steer, Julie Morgan, Mark Davies, Philip Carter, Arlo Upton, Stephen Y.C. Tong, John Fraser and Nicole J Moreland

    Citation: BMC Infectious Diseases 2016 16:561

    Content type: Research article

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  18. In the absence of an adult vaccination register, coverage estimates for influenza and pneumococcal vaccination come from surveys and other data sources.

    Authors: Amalie Dyda, Surendra Karki, Andrew Hayen, C. Raina MacIntyre, Robert Menzies, Emily Banks, John M. Kaldor and Bette Liu

    Citation: BMC Infectious Diseases 2016 16:515

    Content type: Research article

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  19. The protective capacities of antibodies induced with Haemophilus influenzae type b (Hib) vaccines can be directly assessed in vitro with a Hib-specific serum bactericidal assay (SBA). However, the conventional SB...

    Authors: Han Wool Kim, Kyung-Hyo Kim, JiHye Kim and Moon H. Nahm

    Citation: BMC Infectious Diseases 2016 16:473

    Content type: Research article

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  20. The effect of previous natural pandemic H1N1 (H1N1 pdm09) influenza infection on the immunogenicity to subsequent inactivated influenza vaccination in children has not been well studied. We aimed to evaluate t...

    Authors: Eun Kyeong Kang, Byung Wook Eun, Nam Hee Kim, Jung Sub Lim, Jun Ah Lee and Dong Ho Kim

    Citation: BMC Infectious Diseases 2016 16:438

    Content type: Research article

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  21. Like other countries in Asia, measles-rubella (MR) vaccine coverage in Bangladesh is suboptimal whereas 90–95 % coverage is needed for elimination of these diseases. The Ministry of Health and Family Welfare (...

    Authors: Md Jasim Uddin, Gourab Adhikary, Md Wazed Ali, Shahabuddin Ahmed, Md Shamsuzzaman, Chris Odell, Lauren Hashiguchi, Stephen S. Lim and Nurul Alam

    Citation: BMC Infectious Diseases 2016 16:411

    Content type: Research article

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  22. The effect of pneumococcal conjugate vaccines (PCV) on invasive pneumococcal disease is frequently reported, but the impact on upper respiratory tract infections in a clinical setting is less documented. Our a...

    Authors: Nils Littorin, Jonas Ahl, Fabian Uddén, Fredrik Resman and Kristian Riesbeck

    Citation: BMC Infectious Diseases 2016 16:407

    Content type: Research article

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  23. Despite the successes of routine national childhood vaccination programmes, measles remains a public health concern. The purpose of this paper is to investigate how patterns of parental attitudes are linked to...

    Authors: Carine Weiss, Daniel Schröpfer and Sonja Merten

    Citation: BMC Infectious Diseases 2016 16:400

    Content type: Research article

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  24. Scotland introduced PCV7 and PCV13 immunisation in young children in 2006 and 2010 respectively. One recent study from the United States reported a decrease in hospitalisation rates for all-cause pneumonia mos...

    Authors: Harish Nair, Arun Thor Watts, Linda J. Williams, Saad B. Omer, Colin R. Simpson, Lorna J. Willocks, J. Claire Cameron and Harry Campbell

    Citation: BMC Infectious Diseases 2016 16:390

    Content type: Research article

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  25. Vaccine-associated paralytic poliomyelitis (VAPP) and immunodeficient long-term polio excretors constitute a significant public health burden and are a major concern for the WHO global polio eradication endgame.

    Authors: Thomas Foiadelli, Salvatore Savasta, Andrea Battistone, Majlinda Kota, Carolina Passera, Stefano Fiore, Silvia Bino, Concetta Amato, Alessandro Lozza, Gian Luigi Marseglia and Lucia Fiore

    Citation: BMC Infectious Diseases 2016 16:277

    Content type: Case report

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  26. The endgame for polio eradication includes coordinated global cessation of oral poliovirus vaccine (OPV), starting with the cessation of vaccine containing OPV serotype 2 (OPV2) by switching all trivalent OPV ...

    Authors: Radboud J. Duintjer Tebbens, Lee M. Hampton and Kimberly M. Thompson

    Citation: BMC Infectious Diseases 2016 16:237

    Content type: Research article

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  27. The endgame for polio eradication involves coordinated global cessation of oral poliovirus vaccine (OPV) with cessation of serotype 2 OPV (OPV2 cessation) implemented in late April and early May 2016 and cessa...

    Authors: Radboud J. Duintjer Tebbens, Lee M. Hampton and Kimberly M. Thompson

    Citation: BMC Infectious Diseases 2016 16:231

    Content type: Research article

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  28. Migrant travellers who return to their country of origin to visit family and friends (VFR) are less likely to seek travel-related medical care and are less likely to adhere to recommended medications and trave...

    Authors: Holly Seale, Rajneesh Kaur, Abela Mahimbo, C. Raina MacIntyre, Nicholas Zwar, Mitchell Smith, Heather Worth and Anita E Heywood

    Citation: BMC Infectious Diseases 2016 16:213

    Content type: Research article

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  29. The present study aimed to identify factors affecting vaccination against influenza among health professionals.

    Authors: Süheyl Asma, Hülya Akan, Yücel Uysal, A. Gürhan Poçan, Mustafa Haki Sucaklı, Erhan Yengil, Çiğdem Gereklioğlu, Aslı Korur, İbrahim Başhan, A. Ferit Erdogan, A. Kürşat Özşahin and Altuğ Kut

    Citation: BMC Infectious Diseases 2016 16:192

    Content type: Research article

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  30. After the global implementation of national immunization programs for prevention of measles, mumps, and rubella (MMR), the prevalences of protective antibodies to these viruses are high in general population. ...

    Authors: Romanee Chaiwarith, Jutarat Praparattanapan, Khanuengnit Nuket, Wilai Kotarathitithum and Khuanchai Supparatpinyo

    Citation: BMC Infectious Diseases 2016 16:190

    Content type: Research article

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  31. Toxoplasmosis is a worldwide zoonosis caused by the intracellular parasite Toxoplasma gondii. However, no effective vaccine is yet available. Poly(lactide-co-glycolide) polymers can reduce protein degradation and...

    Authors: Nian-Zhang Zhang, Ying Xu, Meng Wang, Jia Chen, Si-Yang Huang, Qi Gao and Xing-Quan Zhu

    Citation: BMC Infectious Diseases 2016 16:168

    Content type: Research article

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  32. HPV is a major cancer-causing factor in both sexes in the cervix, vulva, vagina, anus, penis, oropharynx as well as the causal factor in other diseases such as genital warts and recurrent respiratory papilloma...

    Authors: L. Boiron, E. Joura, N. Largeron, B. Prager and M. Uhart

    Citation: BMC Infectious Diseases 2016 16:153

    Content type: Research article

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  33. The bacteria Streptococcus pneumoniae (pneumococcus) and Haemophilus influenzae type b (Hib) are leading causes of childhood pneumonia and meningitis and are major contributors to worldwide mortality in children ...

    Authors: Jiayu Hu, Xiaodong Sun, Zhuoying Huang, Abram L. Wagner, Bradley Carlson, Jianping Yang, Suwen Tang, Yunyi Li, Matthew L. Boulton and Zhengan Yuan

    Citation: BMC Infectious Diseases 2016 16:149

    Content type: Research article

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  34. Following successful eradication of wild polioviruses and planned globally-coordinated cessation of oral poliovirus vaccine (OPV), national and global health leaders may need to respond to outbreaks from reint...

    Authors: Radboud J. Duintjer Tebbens, Mark A. Pallansch, Steven G. F. Wassilak, Stephen L. Cochi and Kimberly M. Thompson

    Citation: BMC Infectious Diseases 2016 16:137

    Content type: Research article

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  35. Prior to introduction of universal varicella vaccination, it is crucial to gain insight into the willingness to vaccinate among the population. This is because suboptimal national vaccination coverage might in...

    Authors: Alies van Lier, Alma Tostmann, Irene A. Harmsen, Hester E. de Melker, Jeannine L. A. Hautvast and Wilhelmina L. M. Ruijs

    Citation: BMC Infectious Diseases 2016 16:127

    Content type: Research article

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  36. Schistosomiasis is the most important human helminth infection due to its impact on public health. The clinical manifestations are chronic and significantly decrease an individual’s quality of life. Infected i...

    Authors: Alessandra Ricciardi, Kittipos Visitsunthorn, John P. Dalton and Momar Ndao

    Citation: BMC Infectious Diseases 2016 16:112

    Content type: Research article

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  37. Although pertussis has been considered a disease of childhood, it is also recognized as an important respiratory tract infection in adolescents and adults. However, in countries with routine vaccination agains...

    Authors: Nirada Siriyakorn, Pornvimol Leethong, Terapong Tantawichien, Saowalak Sripakdee, Anusak Kerdsin, Surang Dejsirilert and Leilani Paitoonpong

    Citation: BMC Infectious Diseases 2016 16:25

    Content type: Research article

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  38. In Canada both bivalent (bHPV) vaccine and quadrivalent HPV vaccine (qHPV) are authorized for use. In Alberta, while both vaccines are available for private purchase, only qHPV is publicly funded for school gi...

    Authors: Xianfang C. Liu, Christopher A. Bell, Kimberley A. Simmonds, Margaret L. Russell and Lawrence W. Svenson

    Citation: BMC Infectious Diseases 2016 16:15

    Content type: Research article

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  39. The main aim of this study was to evaluate Streptococcus pneumoniae carriage in a group of school-aged children and adolescents with asthma because these results might indicate the theoretical risk of invasive pn...

    Authors: Susanna Esposito, Leonardo Terranova, Maria Francesca Patria, Gian Luigi Marseglia, Michele Miraglia del Giudice, Alessandro Bodini, Alberto Martelli, Eugenio Baraldi, Oscar Mazzina, Claudia Tagliabue, Amelia Licari, Valentina Ierardi, Mara Lelii and Nicola Principi

    Citation: BMC Infectious Diseases 2016 16:12

    Content type: Research article

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  40. Over 20 000 people die from rabies each year in India. At least 95 % of people contract rabies from an infected dog. Annual vaccination of over 70 % of the dog population has eliminated both canine and human r...

    Authors: Andrew D. Gibson, Praveen Ohal, Kate Shervell, Ian G. Handel, Barend M. Bronsvoort, Richard J. Mellanby and Luke Gamble

    Citation: BMC Infectious Diseases 2015 15:589

    Content type: Research article

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  41. The availability of new vaccines can prompt policy makers to consider changes to the routine childhood immunisation programme in the UK. Alterations to one aspect of the schedule may have implications for othe...

    Authors: Sonya Crowe, Martin Utley, Guy Walker, Jasmina Panovska-Griffiths, Peter Grove and Christina Pagel

    Citation: BMC Infectious Diseases 2015 15:585

    Content type: Research article

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  42. During the 2009 influenza A (H1N1) pandemic, a monovalent pandemic strain vaccine containing the oil-in-water adjuvant AS03 (Pandemrix®) was offered to the Norwegian population. The coverage among children rea...

    Authors: Inger Johanne Bakken, Kari Modalsli Aaberg, Sara Ghaderi, Nina Gunnes, Lill Trogstad, Per Magnus and Siri Eldevik Håberg

    Citation: BMC Infectious Diseases 2015 15:506

    Content type: Research article

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  43. The use of molecular diagnostic techniques for the evaluation of the impact of pneumococcal conjugate vaccines (PCVs) has not been documented. We aimed to evaluate the impact of PCVs on invasive pneumococcal d...

    Authors: Stefano Tempia, Nicole Wolter, Cheryl Cohen, Sibongile Walaza, Claire von Mollendorf, Adam L. Cohen, Jocelyn Moyes, Linda de Gouveia, Susan Nzenze, Florette Treurnicht, Marietjie Venter, Michelle J. Groome, Shabir A. Madhi and Anne von Gottberg

    Citation: BMC Infectious Diseases 2015 15:450

    Content type: Research article

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  45. Pneumococcal diseases remain a leading cause of vaccine-preventable death worldwide in children <5 years of age. The seven-valent pneumococcal conjugate vaccine (PCV7) was approved in 2001 in Europe and was in...

    Authors: Myint Tin Tin Htar, Dina Christopoulou and Heinz-Josef Schmitt

    Citation: BMC Infectious Diseases 2015 15:419

    Content type: Debate

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  47. Little is known about factors associated with maintenance of hemagglutinin inhibition (HAI) antibodies after influenza vaccination in older adults.

    Authors: H Keipp Talbot, Laura A Coleman, Yuwei Zhu, Sarah Spencer, Mark Thompson, Po-Yung Cheng, Maria E Sundaram, Edward A Belongia and Marie R Griffin

    Citation: BMC Infectious Diseases 2015 15:195

    Content type: Research article

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  48. Influenza vaccination is recommended for all healthcare personnel (HCP) and most institutions offer vaccination for free and on site. However, medical students do not always have such easy access, and the pred...

    Authors: Birthe A Lehmann, Robert AC Ruiter, Sabine Wicker, Gretchen Chapman and Gerjo Kok

    Citation: BMC Infectious Diseases 2015 15:185

    Content type: Research article

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  49. Several studies suggested that vaccines could have non-specific effects on mortality depending on the type of vaccine. Non-specific effects seem to be different in boys and girls. In this study we want to inve...

    Authors: Tessa M Schurink-van’t Klooster, Mirjam J Knol, Hester E de Melker and Marianne AB van der Sande

    Citation: BMC Infectious Diseases 2015 15:148

    Content type: Research article

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  50. Elderly people are at increased risk for severe influenza illness and constitute therefore a major target-group for seasonal influenza vaccination in most industrialized countries. The aim of this study was to...

    Authors: Cornelius Remschmidt, Thorsten Rieck, Birte Bödeker and Ole Wichmann

    Citation: BMC Infectious Diseases 2015 15:137

    Content type: Research article

    Published on:

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