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Tuberculosis and other mycobacterial diseases

Section edited by Edward Graviss and Eyal Oren 

This section aims to publish studies looking at all aspects of of the prevention, diagnosis and management of tuberculosis and other mycobacterial diseases in humans, including HIV-associated tuberculosis, as well as related molecular genetics, pathophysiology, and epidemiology.

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  1. Content type: Research article

    Tuberculosis (TB) remains a global health problem. Several studies have implicated genetic host factors in predisposing populations to TB disease. In this study, we have selected NSMAF (Neutral Sphingomyelinase A...

    Authors: Mounia Qrafli, Imane Asekkaj, Jamal Eddine Bourkadi, Rajae El Aouad and Khalid Sadki

    Citation: BMC Infectious Diseases 2017 17:712

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  2. Content type: Research article

    Pyrazinamide (PZA) plays a unique role in the treatment for multidrug-resistant tuberculosis (MDR-TB) in both first- and second-line regimens. The aim of this study was to investigate the prevalence and molecu...

    Authors: Yu Pang, Damian Zhu, Huiwen Zheng, Jing Shen, Yan Hu, Jie Liu and Yanlin Zhao

    Citation: BMC Infectious Diseases 2017 17:711

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  3. Content type: Research article

    Forkhead box protein 3 (FoxP3) is an important factor for development and function of Regulatory T cells (Treg). Studies have found an association between common gene polymorphisms in FoxP3 and some infectious di...

    Authors: Elham Beiranvand, Saeid Abediankenari, Soghra Khani, Hamideh Mahmoodzadeh Hosseini, Sirous Zeinali, Behnoush Beiranvand, Mehdi Goudarzi and Sima Sadat Seyedjavadi

    Citation: BMC Infectious Diseases 2017 17:673

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  4. Content type: Commentary

    A recently published Ugandan study on tuberculosis (TB) diagnosis in HIV-positive patients with presumptive smear-negative TB, which showed that out of 90 patients who started TB treatment, 20% (18/90) had a p...

    Authors: Tom Decroo, Aquiles R. Henríquez-Trujillo, Anja De Weggheleire and Lutgarde Lynen

    Citation: BMC Infectious Diseases 2017 17:674

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  5. Content type: Research article

    Reported tuberculosis (TB) incidence globally continues to be heavily influenced by expert opinion of case detection rates and ecological estimates of disease duration. Both approaches are recognised as having...

    Authors: Debebe Shaweno, James M. Trauer, Justin T. Denholm and Emma S. McBryde

    Citation: BMC Infectious Diseases 2017 17:662

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  6. Content type: Technical advance

    Maintaining the quality of clinical specimens for tuberculosis (TB) testing is a major challenge in many high TB burden-limited resources countries. Sample referral systems in low and middle income countries a...

    Authors: Elisa Tagliani, Riccardo Alagna, Silva Tafaj, Hasan Hafizi and Daniela Maria Cirillo

    Citation: BMC Infectious Diseases 2017 17:663

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  7. Content type: Research article

    Interim treatment outcomes at 6-months for multidrug-resistant tuberculosis (MDR-TB) treatment are among the most basic performance monitoring and key evaluation indicators in the Stop and End TB strategy of t...

    Authors: Muhammad Atif, Arslan Bashir, Nafees Ahmad, Razia Kaneez Fatima, Sehar Saba and Shane Scahill

    Citation: BMC Infectious Diseases 2017 17:655

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  8. Content type: Research article

    Since the recent introduction of GeneXepert for the detection of Tuberculosis (TB) drug resistance mutations in both primary resistance and acquired resistance in Zambia, little has been documented in literatu...

    Authors: Sepiso K. Masenga, Harrison Mubila and Benson M. Hamooya

    Citation: BMC Infectious Diseases 2017 17:640

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  9. Content type: Research article

    Sub-Saharan Africa continues to document high pediatric tuberculosis (TB) burden, especially among the urban poor. One recommended preventive strategy involves tracking and isoniazid preventive therapy (IPT) f...

    Authors: Florence Nafula Okwara, John Paul Oyore, Fred Nabwire Were and Samson Gwer

    Citation: BMC Infectious Diseases 2017 17:623

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  10. Content type: Research article

    The relatively simple and cheaper light-emitting diode fluorescent microscopy (LED-FM) was recommended by the World Health Organization (WHO) to replace the conventional tuberculosis (TB) microscopy in both hi...

    Authors: Alemu Gadissa Gelalcha, Abebaw Kebede and Hassen Mamo

    Citation: BMC Infectious Diseases 2017 17:613

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  11. Content type: Research article

    Concurrent diabetes mellitus and tuberculosis represent a significant health problem worldwide. Patients with diabetes mellitus have a high risk of tuberculosis, which may be mediated by an abnormal innate imm...

    Authors: María Teresa Herrera, Yolanda Gonzalez, Fernando Hernández-Sánchez, Guadalupe Fabián-San Miguel and Martha Torres

    Citation: BMC Infectious Diseases 2017 17:610

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  12. Content type: Research article

    Every year, over 1 million people develop isoniazid (INH) resistant tuberculosis (TB). Yet, the optimal treatment regimen remains unclear. Given increasing prevalence, the clinical efficacy of regimens used by...

    Authors: Kamila Romanowski, Leslie Y. Chiang, David Z. Roth, Mel Krajden, Patrick Tang, Victoria J. Cook and James C. Johnston

    Citation: BMC Infectious Diseases 2017 17:604

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  13. Content type: Research article

    In the search for fast, simple and better ways for diagnosis of tuberculosis (TB), there is need to discover and evaluate new biomarkers that are found in samples other than sputum to determine their effective...

    Authors: Anna Ritah Namuganga, Novel N. Chegou, Paul Mubiri, Gerhard Walzl and Harriet Mayanja-Kizza

    Citation: BMC Infectious Diseases 2017 17:600

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  14. Content type: Research article

    The relative fitness of organisms causing drug-susceptible (DS) and multidrug-resistant (MDR) tuberculosis (TB) is unclear. We compared the risk of TB infection and TB disease in young child household contacts...

    Authors: Vera Golla, Kathryn Snow, Anna M. Mandalakas, H. Simon Schaaf, Karen Du Preez, Anneke C. Hesseling and James A. Seddon

    Citation: BMC Infectious Diseases 2017 17:593

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    The Correction to this article has been published in BMC Infectious Diseases 2017 17:713

  15. Content type: Research article

    Globally, almost 40% of tuberculosis (TB) patients remain undiagnosed, and those that are diagnosed often experience prolonged delays before initiating correct treatment, leading to ongoing transmission. While...

    Authors: Richard James, Keovathanak Khim, Lydia Boudarene, Joanne Yoong, Chea Phalla, Saly Saint, Pichenda Koeut, Tan Eang Mao, Richard Coker and Mishal Sameer Khan

    Citation: BMC Infectious Diseases 2017 17:580

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  16. Content type: Research article

    Emergence of Multidrug-resistant (MDR) strains constitutes a significant public health problem worldwide. Prevalence of MDR tuberculosis from Chad is unavailable to date.

    Authors: Awa Ba Diallo, Gedeon W. Ossoga, Geraldine Daneau, Seynabou Lo, Richard Ngandolo, Colette Diguimbaye Djaibé, Barou Djouater, Souleymane Mboup, Bouke C. de Jong, Aissatou G. Diallo and Florian Gehre

    Citation: BMC Infectious Diseases 2017 17:579

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  17. Content type: Research article

    Although the incidence of tuberculosis (TB) in most parts of China are well under control now, in less developed areas such as Qinghai, TB still remains a major public health problem. This study aims to reveal...

    Authors: Huaxiang Rao, Xinyu Shi and Xi Zhang

    Citation: BMC Infectious Diseases 2017 17:578

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  18. Content type: Research article

    In household contact investigations of tuberculosis (TB), a second tuberculin skin test (TST) obtained several weeks after a first negative result consistently identifies individuals that undergo TST conversio...

    Authors: Edward C. Jones-López, Carlos Acuña-Villaorduña, Geisa Fregona, Patricia Marques-Rodrigues, Laura F. White, David Jamil Hadad, Lucilia Pereira Dutra-Molina, Solange Vinhas, Avery I. McIntosh, Mary Gaeddert, Rodrigo Ribeiro-Rodrigues, Padmini Salgame, Moises Palaci, David Alland, Jerrold J. Ellner and Reynaldo Dietze

    Citation: BMC Infectious Diseases 2017 17:576

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  19. Content type: Research article

    The worldwide emergence of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) has posed additional challenges for global tuberculosis (TB) control efforts, as limite...

    Authors: Kefyalew Addis Alene, Hengzhong Yi, Kerri Viney, Emma S. McBryde, Kunyun Yang, Liqiong Bai, Darren J. Gray, Archie C. A. Clements and Zuhui Xu

    Citation: BMC Infectious Diseases 2017 17:573

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  20. Content type: Research article

    The existence of a bi-directional relationship between tuberculosis (TB) and insulin resistance (IR)/diabetes has been alluded to in literature. Although diabetes has been linked to increased tuberculosis risk...

    Authors: Lauren Philips, Janicke Visser, Daan Nel and Renée Blaauw

    Citation: BMC Infectious Diseases 2017 17:570

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