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Tuberculosis and other mycobacterial diseases

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of tuberculosis and other mycobacterial diseases in humans, including HIV-associated tuberculosis, as well as related molecular genetics, pathophysiology, and epidemiology.

Page 14 of 18

  1. Early diagnosis and prompt effective therapy are crucial for the prevention of tuberculosis (TB) transmission, particularly in regions with high levels of multi-drug resistant TB. This study aimed to evaluate ...

    Authors: Tatiana V Belkina, Doniyor S Khojiev, Mirzagaleb N Tillyashaykhov, Zinaida N Tigay, Marat U Kudenov, Jurjen Duintjer Tebbens and Jiri Vlcek

    Citation: BMC Infectious Diseases 2014 14:624

    Content type: Research article

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  2. Tuberculosis (TB) during pregnancy may lead to severe consequences affecting both mother and child. Prenatal care could be a very good opportunity for TB care, especially for women who have limited access to h...

    Authors: Hang Thanh Nguyen, Chiara Pandolfini, Peter Chiodini and Maurizio Bonati

    Citation: BMC Infectious Diseases 2014 14:617

    Content type: Research article

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  3. We aimed to investigate the molecular epidemiology of Mycobacterium tuberculosis complex (MTBC) isolates in the province of Palermo, Sicily, Italy, by characterizing 183 isolates identified in the years 2004-2012...

    Authors: Celestino Bonura, Michel K Gomgnimbou, Guislaine Refrégier, Aurora Aleo, Teresa Fasciana, Anna Giammanco, Christophe Sola and Caterina Mammina

    Citation: BMC Infectious Diseases 2014 14:602

    Content type: Research article

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  4. Non-tuberculous mycobacteria (NTM), which are ubiquitous micro-organisms occurring in humans, animals and the environment, sometimes receive public health and veterinary attention as opportunistic disease-caus...

    Authors: Bugwesa Z Katale, Erasto V Mbugi, Louise Botha, Julius D Keyyu, Sharon Kendall, Hazel M Dockrell, Anita L Michel, Rudovick R Kazwala, Mark M Rweyemamu, Paul van Helden and Mecky I Matee

    Citation: BMC Infectious Diseases 2014 14:616

    Content type: Research article

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  5. India has generally used 1 TU purified protein derivative (PPD) as opposed to 2 TU PPD globally, limiting comparisons. It is important to assess latent TB infection in adolescents given that they may be a targ...

    Authors: Dharma Rao Uppada, Sumithra Selvam, Nelson Jesuraj, Sean Bennett, Suzanne Verver, Harleen MS Grewal and Mario Vaz

    Citation: BMC Infectious Diseases 2014 14:571

    Content type: Research article

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  6. The diagnosis and treatment of latent tuberculosis infection (LTBI) have become mandatory to reduce the burden of tuberculosis worldwide. Close contacts of active TB patients are at high risk of both active an...

    Authors: Seung Jun Lee, Seung Hun Lee, You Eun Kim, Yu Ji Cho, Yi Yeong Jeong, Ho Cheol Kim, Jong Deog Lee, Jang Rak Kim, Young Sil Hwang, Hee Jin Kim and Dick Menzies

    Citation: BMC Infectious Diseases 2014 14:566

    Content type: Research article

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  7. The Xpert MTB/RIF assay (Xpert assay; Cepheid, Sunnyvale, CA) is becoming the test of choice for the rapid diagnosis of tuberculosis and rifampin (RIF) resistance. The aim of this study was to evaluate the per...

    Authors: Hee Jae Huh, Byeong-Ho Jeong, Kyeongman Jeon, Won-Jung Koh, Chang-Seok Ki and Nam Yong Lee

    Citation: BMC Infectious Diseases 2014 14:589

    Content type: Research article

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  8. Iatrogenic skin and soft tissue infections by rapidly growing mycobacteria are described with increasing frequency, especially among immunocompromised patients.

    Authors: Nguyen Phu Huong Lan, Marion-Eliëtte Kolader, Nguyen Van Dung, James I Campbell, Nguyen thi Tham, Nguyen Van Vinh Chau, H Rogier van Doorn and Dien Hoa Le

    Citation: BMC Infectious Diseases 2014 14:550

    Content type: Case report

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  9. Obesity is known to affect cell-mediated immune responses. Recent studies have revealed that genetic polymorphisms in the fat mass and obesity associated (FTO) gene are related to human obesity. We hypothesize th...

    Authors: Yan Feng, Fengliang Wang, Hongqiu Pan, Sangsang Qiu, Jieqiong Lü, Liang Wu, Jianming Wang and Cheng Lu

    Citation: BMC Infectious Diseases 2014 14:592

    Content type: Research article

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  10. To compare epidemiological data between recurrent cases after cure (RC), distinguishing relapse from reinfection, after dropout (RD) and new cases (NC) in an ambulatory setting in a TB-endemic country.

    Authors: Gisela Unis, Andrezza Wolowski Ribeiro, Leonardo Souza Esteves, Fernanda Sá Spies, Pedro Dornelles Picon, Elis Regina Dalla Costa and Maria Lucia Rosa Rossetti

    Citation: BMC Infectious Diseases 2014 14:548

    Content type: Research article

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  11. To inform the choice of an appropriate screening and diagnostic algorithm for tuberculosis (TB) screening initiatives in different epidemiological settings, we compare algorithms composed of currently availabl...

    Authors: Anna H van’t Hoog, Ikushi Onozaki and Knut Lonnroth

    Citation: BMC Infectious Diseases 2014 14:532

    Content type: Research article

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  12. Effective protocols for the isolation and de-isolation of patients with suspected pulmonary tuberculosis (PTB) are essential determinants of health-care costs. Early de-isolation needs to be balanced with the ...

    Authors: Shirin Kalimuddin, Jeanne MM Tan, Ban Hock Tan and Jenny GH Low

    Citation: BMC Infectious Diseases 2014 14:547

    Content type: Research article

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  13. Aminoglycosides are a critical component of multidrug-resistant tuberculosis (MDR-TB) treatment but data on their efficacy and adverse effects in Botswana is scarce. We determined the effect of amikacin on tre...

    Authors: Chawangwa Modongo, Rafal S Sobota, Boikobo Kesenogile, Ronald Ncube, Giorgio Sirugo, Scott M Williams and Nicola M Zetola

    Citation: BMC Infectious Diseases 2014 14:542

    Content type: Research article

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  14. The clinical course of tuberculosis (TB) infection, bacterial load and the morphology of lesions vary between pulmonary and extrapulmonary TB. Antigens expressed in abundance during infection could represent r...

    Authors: Tehmina Mustafa, Nils Anders Leversen, Lisbet Sviland and Harald Gotten Wiker

    Citation: BMC Infectious Diseases 2014 14:535

    Content type: Research article

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  15. Environmental exposure is a likely risk factor for the development of pulmonary Mycobacterium avium complex (MAC) disease. The influence of environmental exposure on the response to antimicrobial treatment and re...

    Authors: Yutaka Ito, Toyohiro Hirai, Kohei Fujita, Takeshi Kubo, Koichi Maekawa, Satoshi Ichiyama, Kaori Togashi and Michiaki Mishima

    Citation: BMC Infectious Diseases 2014 14:522

    Content type: Research article

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  16. International travel from low-incidence to high-incidence countries for tuberculosis (TB) is regarded as a risk factor for acquiring TB infection. In this prospective study among long-term travellers we examin...

    Authors: Floor Elfrink, Anneke van den Hoek, Marlies E Mensen and Gerard JB Sonder

    Citation: BMC Infectious Diseases 2014 14:515

    Content type: Research article

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  17. There has been a long held belief that patients with drug-susceptible TB are non-infectious after two weeks of therapy. Recent microbiological and epidemiological evidence has challenged this dogma, however, t...

    Authors: Gloria Ivy Mensah, Kennedy Kwasi Addo, John Amissah Tetteh, Sandra Sowah, Thomas Loescher, Christof Geldmacher and Dolly Jackson-Sillah

    Citation: BMC Infectious Diseases 2014 14:495

    Content type: Research article

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  18. Introduction of Xpert® MTB/RIF assay has revolutionalised the diagnosis of tuberculosis (TB) by simultaneously detecting the bacteria and resistance to rifampicin (rif), a surrogate marker for multi-drug resistan...

    Authors: Gerald Mboowa, Carolyn Namaganda and Willy Ssengooba

    Citation: BMC Infectious Diseases 2014 14:481

    Content type: Research article

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  19. Tuberculosis (TB) in both animals and humans is caused by Mycobacterium tuberculosis complex (MTBC) primarily transmitted by inhalation of aerosolized droplets containing the organism. Multi-drug resistance (MDR)...

    Authors: Nolwazi L Bhembe, Uchechukwu U Nwodo, Sharlene Govender, Cindy Hayes, Roland N Ndip, Anthony I Okoh and Ezekiel Green

    Citation: BMC Infectious Diseases 2014 14:479

    Content type: Research article

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  20. The spread of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Mycobacterium tuberculosis compromises effective control of tuberculosis (TB) in Siberia. Early identification of drug-resistant isolat...

    Authors: Maya A Dymova, Andrey G Cherednichenko, Olga I Alkhovik, Eugeny A Khrapov, Tatjana I Petrenko and Maxim L Filipenko

    Citation: BMC Infectious Diseases 2014 14:478

    Content type: Research article

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  21. Molecular epidemiology of Mycobacterium tuberculosis, its transmission dynamics and population structure have become important determinants of targeted tuberculosis control programs. Here we describe recent chang...

    Authors: Ulziijargal Gurjav, Peter Jelfs, Nadine McCallum, Ben J Marais and Vitali Sintchenko

    Citation: BMC Infectious Diseases 2014 14:455

    Content type: Research article

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  22. We aimed to evaluate urinary MCP-1 and oxidative stress through urinary malondialdehyde (MDA) in leprosy and correlate them with traditional, but less sensitive markers of renal disease.

    Authors: Gdayllon Cavalcante Meneses, Alexandre Braga Libório, Elizabeth Francesco de Daher, Geraldo Bezerra da Silva Jr, Marcus Felipe Bezerra da Costa, Maria Araci Andrade Pontes and Alice Maria Costa Martins

    Citation: BMC Infectious Diseases 2014 14:451

    Content type: Research article

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  23. An algorithm instituted following Xpert MTB/RIF (Xpert) introduction in South Africa advocates for treating all Xpert rifampicin resistant patients as MDR-TB cases while awaiting confirmation by phenotypic or ...

    Authors: Nomonde R Dlamini-Mvelase, Lise Werner, Rogerio Phili, Lindiwe P Cele and Koleka P Mlisana

    Citation: BMC Infectious Diseases 2014 14:442

    Content type: Research article

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  24. The objective of this study was to investigate the association between KIR genes and the immunopathogenesis of leprosy.

    Authors: Luciana Ribeiro Jarduli, Hugo Vicentin Alves, Fabiana Covolo de Souza-Santana, Elaine Valim Camarinha Marcos, Ana Carla Pereira, Ida Maria Foschiani Dias-Baptista, Vinícius Medeiros Fava, Marcelo Távora Mira, Milton Ozório Moraes, Marcos da Cunha Lopes Virmond and Jeane Eliete Laguila Visentainer

    Citation: BMC Infectious Diseases 2014 14:438

    Content type: Research article

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  25. While the prevalence of multidrug-resistant (MDR) tuberculosis (TB) is high among children in the Western Cape of South Africa, the psychosocial implications of treatment for children with MDR-TB remain poorly...

    Authors: Caroline Franck, James A Seddon, Anneke C Hesseling, H Simon Schaaf, Donald Skinner and Lucy Reynolds

    Citation: BMC Infectious Diseases 2014 14:426

    Content type: Research article

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  26. In West and Central Africa Buruli ulcer (BU) and HIV co-infection is increasingly recognised and management of these two diseases combined is an emerging challenge for which there is little published informati...

    Authors: Franck Wanda, Patrick Nkemenang, Genevieve Ehounou, Marie Tchaton, Eric Comte, Laurence Toutous Trellu, Isabelle Masouyé, Vanessa Christinet and Daniel P O’Brien

    Citation: BMC Infectious Diseases 2014 14:423

    Content type: Case report

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  27. Nosocomial transmission of pulmonary tuberculosis (PTB) is a problem in resource-limited settings. However, the degree of TB exposure and the intermediate- and long-term morbidity and mortality of hospital-ass...

    Authors: Nicola M Zetola, Nenad Macesic, Chawangwa Modongo, Sanghuk Shin, Ronald Ncube and Ronald G Collman

    Citation: BMC Infectious Diseases 2014 14:409

    Content type: Research article

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    The Erratum to this article has been published in BMC Infectious Diseases 2015 15:211

  28. Pulmonary tuberculosis (PTB) is an infectious disease that involves the lungs and can be lethal in many cases. Tuberculosis (TB) in children represents 5 to 20% of the total TB cases. However, there are few up...

    Authors: Napoleón González Saldaña, Mercedes Macías Parra, Marte Hernández Porras, Pedro Gutiérrez Castrellón, Valeria Gómez Toscano and Hugo Juárez Olguin

    Citation: BMC Infectious Diseases 2014 14:401

    Content type: Research article

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  29. According to the World Health Organization’s recent report, in Malaysia, tuberculosis (TB) treatment success rate for new smear positive pulmonary tuberculosis (PTB) patients is still below the global success ...

    Authors: Muhammad Atif, Syed Azhar Syed Sulaiman, Asrul Akmal Shafie, Irfhan Ali, Muhammad Asif and Zaheer-Ud-Din Babar

    Citation: BMC Infectious Diseases 2014 14:399

    Content type: Research article

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  30. Interferon-gamma release assays have emerged as a more specific alternative to the tuberculin skin test (TST) for detection of tuberculosis (TB) infection, especially in Bacille Calmette-Guérin (BCG) vaccinate...

    Authors: Lilly M Verhagen, Mailis Maes, Julian A Villalba, Adriana d’Alessandro, Lazaro Perez Rodriguez, Mercedes F España, Peter WM Hermans and Jacobus H de Waard

    Citation: BMC Infectious Diseases 2014 14:383

    Content type: Research article

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  31. Due to the increasing prevalence of Mycobacterium tuberculosis strains resistant to one or more antibiotics, there is a need for new quantitative culture methods both for drug susceptibility testing and for valid...

    Authors: Alice L den Hertog, Sandra Menting, Ernst T Smienk, Jim Werngren, Sven Hoffner and Richard M Anthony

    Citation: BMC Infectious Diseases 2014 14:380

    Content type: Research article

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  32. Tuberculosis remains an important health concern in many countries. The aim of this study was to identify predictors of unfavorable outcomes at the end of treatment (EOT) and at the end of study (EOS; 40 month...

    Authors: Hongjo Choi, Myungsun Lee, Ray Y Chen, Youngran Kim, Soyoung Yoon, Joon Sung Joh, Seung Kyu Park, Lori E Dodd, Jongseok Lee, Taeksun Song, Ying Cai, Lisa C Goldfeder, Laura E Via, Matthew W Carroll, Clifton E Barry 3rd and Sang-Nae Cho

    Citation: BMC Infectious Diseases 2014 14:360

    Content type: Research article

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  33. Tuberculosis (TB) is one of the most prevalent infectious diseases affecting millions worldwide. The currently available anti-TB drugs and vaccines have proved insufficient to contain this scourge, necessitati...

    Authors: Sachin Kumar Samuchiwal, Sultan Tousif, Dhiraj Kumar Singh, Arun Kumar, Anamika Ghosh, Kuhulika Bhalla, Prem Prakash, Sushil Kumar, Maitree Bhattacharyya, Prashini Moodley, Gobardhan Das and Anand Ranganathan

    Citation: BMC Infectious Diseases 2014 14:355

    Content type: Research article

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  34. Despite sustained exposure to a person with pulmonary tuberculosis (TB), some M. tuberculosis (Mtb) exposed individuals maintain a negative tuberculin skin test (TST). Our objective was to characterize these pers...

    Authors: Ningning Ma, Sarah Zalwango, LaShaunda L Malone, Mary Nsereko, Eddie M Wampande, Bonnie A Thiel, Brenda Okware, Robert P Igo Jr., Moses L Joloba, Ezekiel Mupere, Harriet Mayanja-Kizza, W Henry Boom and Catherine M Stein

    Citation: BMC Infectious Diseases 2014 14:352

    Content type: Research article

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  35. Tuberculosis remains a high burden for Human society despite considerable investments in its control. Unique features in the history of infection and transmission dynamics of tuberculosis pose serious limitati...

    Authors: Joao Sollari Lopes, Paula Rodrigues, Suani TR Pinho, Roberto FS Andrade, Raquel Duarte and M Gabriela M Gomes

    Citation: BMC Infectious Diseases 2014 14:340

    Content type: Research article

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  36. The present study was aimed to evaluate whether IgG, IgM and IgA antibodies levels detected against a novel Mycobacterium tuberculosis polyprotein 38 F-64 F (with 38 F being the abbreviation for 38kD-ESAT6-CFP10 ...

    Authors: Xiaoyan Feng, Xiqin Yang, Bingshui Xiu, Shuang Qie, Zhenhua Dai, Kun Chen, Ping Zhao, Li Zhang, Russell A Nicholson, Guohua Wang, Xiaoguo Song and Heqiu Zhang

    Citation: BMC Infectious Diseases 2014 14:336

    Content type: Research article

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  37. There is increasing evidence that community-based treatment of drug resistant tuberculosis (DRTB) is a feasible and cost-effective alternative to centralized, hospital-based care. Although several large progra...

    Authors: Pamela Weiss, Wenjia Chen, Victoria J Cook and James C Johnston

    Citation: BMC Infectious Diseases 2014 14:333

    Content type: Research article

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  38. This study assesses the risk of LTBI at our Hospital among HCWs who have been exposed to TB patients with a delayed diagnosis and respiratory protection measures were not implemented.

    Authors: Alba Muzzi, Elena Seminari, Tiziana Feletti, Luigia Scudeller, Piero Marone, Carmine Tinelli, Lorenzo Minoli, Carlo Marena, Patrizia Mangiarotti and Maurizio Strosselli

    Citation: BMC Infectious Diseases 2014 14:324

    Content type: Research article

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  39. There is increasing evidence to suggest that different Mycobacterium tuberculosis lineages cause variations in the clinical presentation of tuberculosis (TB). Certain M. tuberculosis genotypes/lineages have been ...

    Authors: Ruth Stavrum, George PrayGod, Nyagosya Range, Daniel Faurholt-Jepsen, Kidola Jeremiah, Maria Faurholt-Jepsen, Henrik Krarup, Martine G Aabye, John Changalucha, Henrik Friis, Aase B Andersen and Harleen MS Grewal

    Citation: BMC Infectious Diseases 2014 14:309

    Content type: Research article

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  40. The occurrence of tuberculosis (TB) among children has long been neglected as a public health concern. However, any child with TB is a sentinel event indicating recent transmission. Vaccination, early case fin...

    Authors: Connie GM Erkens, Gerard de Vries, Sytze T Keizer, Erika Slump and Susan van den Hof

    Citation: BMC Infectious Diseases 2014 14:295

    Content type: Research article

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  41. Uptake of isoniazid preventive therapy (IPT) to prevent tuberculosis has been poor, particularly in the highest risk populations. Interventions to improve IPT delivery could promote implementation. The large n...

    Authors: Lisa V Adams, Elizabeth A Talbot, Karen Odato, Heather Blunt and Karen R Steingart

    Citation: BMC Infectious Diseases 2014 14:281

    Content type: Research article

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  42. The epidemiology of infections with nontuberculous mycobacteria (NTM) has been changing and the incidence has been increasing in some settings. The main route of transmission to humans is considered to be from...

    Authors: Michael P Chou, Archie CA Clements and Rachel M Thomson

    Citation: BMC Infectious Diseases 2014 14:279

    Content type: Research article

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  43. Health promotion for prevention and control of Tuberculosis (TB) is implemented worldwide because of its importance, but few reports have evaluated its impact on behavior due to a lack of standard outcome indi...

    Authors: Ying Li, John Ehiri, Daiyu Hu, Yanqi Zhang, Qingya Wang, Shun Zhang and Jia Cao

    Citation: BMC Infectious Diseases 2014 14:268

    Content type: Research article

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  44. Neutrophils (PMN) are the first cells to infiltrate the lung after infection, and they play a significant protective role in the elimination of pathogen, by releasing preformed oxidants and proteolytic enzymes...

    Authors: María Mercedes Romero, Juan Ignacio Basile, Beatriz López, Viviana Ritacco, Lucía Barrera, María del Carmen Sasiain and Mercedes Alemán

    Citation: BMC Infectious Diseases 2014 14:262

    Content type: Research article

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  45. The aim of the study was to assess the correlation between the tuberculin skin test (TST) and in vitro interferon-gamma released assays (IGRAs) with risk factors for the spread of infection in smear positive pulm...

    Authors: Maria Luiza de Souza-Galvão, Irene Latorre, Neus Altet-Gómez, María Ángeles Jiménez-Fuentes, Celia Milà, Jordi Solsona, Maria Asunción Seminario, Adela Cantos, Juan Ruiz-Manzano and José Domínguez

    Citation: BMC Infectious Diseases 2014 14:258

    Content type: Research article

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  46. Genetic factors are involved in susceptibility or protection to tuberculosis (TB). Apart from gene polymorphisms and mutations, changes in levels of gene expression, induced by non-genetic factors, may also de...

    Authors: Adane Mihret, Andre G Loxton, Yonas Bekele, Stefan HE Kaufmann, Martin Kidd, Mariëlle C Haks, Tom HM Ottenhoff, Abraham Aseffa, Rawleigh Howe and Gerhard Walzl

    Citation: BMC Infectious Diseases 2014 14:257

    Content type: Research article

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  47. Bacterial infection is a well-known risk of breast implant surgery. It is typically caused by bacterial skin flora, specifically Staphylococcus aureus and the coagulase negative staphylococci. There have been inf...

    Authors: David Atallah, Nadine El Kassis, George Araj, Marwan Nasr, Roy Nasnas, Nicolas Veziris and Dolla Sarkis

    Citation: BMC Infectious Diseases 2014 14:238

    Content type: Case report

    Published on:

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