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Tuberculosis and other mycobacterial diseases

Section edited by Edward Graviss and Eyal Oren 

This section aims to publish studies looking at all aspects of of the prevention, diagnosis and management of tuberculosis and other mycobacterial diseases in humans, including HIV-associated tuberculosis, as well as related molecular genetics, pathophysiology, and epidemiology.

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  1. Content type: Research article

    Globally, 40% of all tuberculosis (TB) cases, 65% paediatric cases and 75% multi-drug resistant TB (MDR-TB) cases are missed due to underreporting and/or under diagnosis. A recent Kenyan TB prevalence survey f...

    Authors: J. N. Oliwa, J. Maina, P. Ayieko, D. Gathara, I. A. Kathure, E. Masini, A. H. van’t Hoog, M. B. van Hensbroek and M. English

    Citation: BMC Infectious Diseases 2018 18:328

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  2. Content type: Research article

    The incidence and severity of tuberculosis chemotherapy toxicity is poorly characterised. We used data available from patients in the REMoxTB trial to provide an assessment of the risks associated with the sta...

    Authors: Conor D. Tweed, Angela M. Crook, Evans I. Amukoye, Rodney Dawson, Andreas H. Diacon, Madeline Hanekom, Timothy D. McHugh, Carl M. Mendel, Sarah K. Meredith, Michael E. Murphy, Saraswathi E. Murthy, Andrew J. Nunn, Patrick P. J. Phillips, Kasha P. Singh, Melvin Spigelman, Genevieve H. Wills…

    Citation: BMC Infectious Diseases 2018 18:317

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  3. Content type: Research article

    Indonesia ranking third in the world, regarding leprosy burden. Chemoprophylaxis is effective in reducing risk of developing leprosy among contacts. ‘Blanket approach’ is an operational strategy for leprosy po...

    Authors: Anuj Tiwari, Steaven Dandel, Rita Djupuri, Liesbeth Mieras and Jan Hendrik Richardus

    Citation: BMC Infectious Diseases 2018 18:324

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  4. Content type: Research article

    Nontuberculous mycobacteria (NTM) infections in patients with cystic fibrosis (CF) is increasing globally. However, the related epidemiology, comorbidities, and clinical impact of NTM infection remains unclear...

    Authors: Maxine S. Eikani, Melodee Nugent, Arash Poursina, Pippa Simpson and Hara Levy

    Citation: BMC Infectious Diseases 2018 18:311

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  5. Content type: Case report

    Although paradoxical reactions (PRs) to anti-tuberculosis (anti-TB) therapy during treatment are well-established occurrences, PRs presenting as a new lesion after the completion of treatment are extremely rar...

    Authors: Akira Machida, Tasuku Ishihara, Eiichiro Amano and Shinichi Otsu

    Citation: BMC Infectious Diseases 2018 18:313

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  6. Content type: Research article

    Female genital tuberculosis (FGTB) is known to cause severe tubal disease leading to infertility and its incidence closely parallels with the overall prevalence of tuberculosis (TB) in a community. Its magnitu...

    Authors: Sileshi Abdissa, Tamrat Abebe, Gobena Ameni, Sisay Teklu, Yonas Bekuretsion, Markos Abebe and Adane Mihret

    Citation: BMC Infectious Diseases 2018 18:304

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  7. Content type: Research article

    We have previously shown that 8 weeks’ treatment with phenylbutyrate (PBA) (500mgx2/day) with or without vitamin D3 (vitD3) (5000 IU/day) as host-directed therapy (HDT) accelerated clinical recovery, sputum cultu...

    Authors: Rokeya Sultana Rekha, Akhirunnesa Mily, Tajnin Sultana, Ahsanul Haq, Sultan Ahmed, S. M. Mostafa Kamal, Annemarie van Schadewijk, Pieter S. Hiemstra, Gudmundur H. Gudmundsson, Birgitta Agerberth and Rubhana Raqib

    Citation: BMC Infectious Diseases 2018 18:303

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  8. Content type: Research article

    Efficient and effective strategies for identifying cases of active tuberculosis (TB) in rural sub-Saharan Africa are lacking. Household contact tracing offers a potential approach to diagnose more TB cases, an...

    Authors: Kristen M. Little, Reginah Msandiwa, Neil Martinson, Jonathan Golub, Richard Chaisson and David Dowdy

    Citation: BMC Infectious Diseases 2018 18:299

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  9. Content type: Case report

    Tuberculous (TB) pneumonia can induce acute respiratory distress syndrome (ARDS). Although TB pneumonia is one of the causes of disease and death among children worldwide, the literature on TB pneumonia-induce...

    Authors: Dong Tien Ngo, Phuc Huu Phan, Shoji Kawachi, Noriko Nakajima, Naoyuki Hirata, Akira Ainai, Thuy Thi Bich Phung, Dien Minh Tran and Hai Thanh Le

    Citation: BMC Infectious Diseases 2018 18:294

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  10. Content type: Case report

    Although intravesical bacille Calmette-Guérin (BCG) therapy is accepted as an effective treatment for bladder cancer, serious complications may occur in rare cases. To date, only 4 cases have been reported in ...

    Authors: Takuya Kusakabe, Kenji Endo, Itaru Nakamura, Hidekazu Suzuki, Hirosuke Nishimura, Shinji Fukushima and Kengo Yamamoto

    Citation: BMC Infectious Diseases 2018 18:290

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  11. Content type: Research article

    Tuberculosis (TB) case finding is an important component of TB control because it can reduce transmission of Mycobacterium tuberculosis (MTB) through prompt detection and treatment of infectious patients.

    Authors: Godfrey Bigogo, Kevin Cain, Diana Nyole, Geoffrey Masyongo, Joshua Auko Auko, Newton Wamola, Albert Okumu, Janet Agaya, Joel Montgomery, Martien Borgdorff and Deron Burton

    Citation: BMC Infectious Diseases 2018 18:262

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  12. Content type: Research article

    Limited treatment options of extensive drug-resistant tuberculosis (XDR-TB) have led to its high mortality worldwide. Relevant data about mortality of XDR-TB patients in literature are limited and likely under...

    Authors: Chengli Bei, Manjiao Fu, Yao Zhang, Hebin Xie, Ke Yin, Yanke Liu, Li Zhang, Bangruan Xie, Fang Li, Hua Huang, Yuhong Liu, Li Yang and Jing Zhou

    Citation: BMC Infectious Diseases 2018 18:261

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  13. Content type: Research article

    The recurrence of tuberculosis (TB) disease in treated patients can serve as a marker of the efficacy of TB control programs. Recurrent disease represents either endogenous reactivation with the same strain of My...

    Authors: Laila Parvaresh, Taryn Crighton, Elena Martinez, Andrea Bustamante, Sharon Chen and Vitali Sintchenko

    Citation: BMC Infectious Diseases 2018 18:265

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  14. Content type: Research article

    Tuberculosis is among the top ten cause of death (9th) from a single infectious agent worldwide. It even ranks above HIV/AIDS. It is among the top 10 causes of death among children. Globally there are estimate...

    Authors: Bereket Gebremichael, Tsega-Ab Abebaw, Tsedey Moges, Admas Abera Abaerei and Nadia Worede

    Citation: BMC Infectious Diseases 2018 18:252

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  15. Content type: Research article

    Ethiopia is one of the world health organization defined higher tuberculosis (TB) burden countries where the disease remains a massive public health threat. This study aimed to identify the prevalence and asso...

    Authors: Biresaw Demile, Amare Zenebu, Haile Shewaye, Siqing Xia and Awoke Guadie

    Citation: BMC Infectious Diseases 2018 18:249

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  16. Content type: Research article

    Prior to clinical trials of new TB drugs or therapeutic vaccines, it is necessary to develop monitoring tools to predict treatment outcomes in TB patients. Urine interferon gamma inducible protein 10 (IP-10) i...

    Authors: Song Yee Kim, Jungho Kim, Deok Ryun Kim, Young Ae Kang, Sungyoung Bong, Jonghee Lee, Suyeon Kim, Nam Suk Lee, Bora Sim, Sang-Nae Cho, Young Sam Kim and Hyejon Lee

    Citation: BMC Infectious Diseases 2018 18:240

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  17. Content type: Research article

    With the widespread use of rifampicin and isoniazid, bacterial resistance has become a growing problem. Additionally, the lack of relevant baseline information for the frequency of drug-resistant tuberculosis ...

    Authors: Ming-Jin Zhang, Wen-Zhi Ren, Xue-Juan Sun, Yang Liu, Ke-Wei Liu, Zhong-Hao Ji, Wei Gao and Bao Yuan

    Citation: BMC Infectious Diseases 2018 18:234

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  18. Content type: Case report

    Mycobacterium Avium Complex (MAC) is an established microbiologic cause of pulmonary disease, lymphadenitis, and disseminated disease in cases of advanced immune suppression. However, MAC manifesting as vertebral...

    Authors: Megan E. Gray, Peter W. Liu and Brian Wispelwey

    Citation: BMC Infectious Diseases 2018 18:235

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  19. Content type: Case report

    Mycobacterium arupense, first identified in 2006, is a slow-growing nontuberculous mycobacterium (NTM) and an emerging cause of tenosynovitis, potentially associated with immunosuppression. However, unlike the di...

    Authors: Xian Zhou, Qiaoling Ruan, Weimin Jiang, Xinyu Wang, Yuan Jiang, Shenglei Yu, Yu Xu, Jing Li, Yangyi Zhang, Wenhong Zhang and Yuekai Hu

    Citation: BMC Infectious Diseases 2018 18:221

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