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Tuberculosis and other mycobacterial diseases

Section edited by Edward Graviss and Eyal Oren 

This section aims to publish studies looking at all aspects of of the prevention, diagnosis and management of tuberculosis and other mycobacterial diseases in humans, including HIV-associated tuberculosis, as well as related molecular genetics, pathophysiology, and epidemiology.

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  1. Content type: Research article

    The introduction of Bedaquiline, the first new antimycobacterial drug in over 40 years, has highlighted the critical importance of medication adherence in drug-resistant tuberculosis (DR-TB) treatment to preve...

    Authors: N. Bionghi, A. Daftary, B. Maharaj, Z. Msibi, K. R. Amico, G. Friedland, C. Orrell, N. Padayatchi and M. R. O’Donnell

    Citation: BMC Infectious Diseases 2018 18:171

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  2. Content type: Research article

    Characterization of the Mycobacterium leprae genome has made possible the development of Polymerase Chain Reaction (PCR) systems that can amplify different genomic regions. Increased reliability and technical eff...

    Authors: Rafael Silva Gama, Thalisson Artur Ribeiro Gomides, Chaiana Fróes Magalhães Gama, Suelen Justo Maria Moreira, Fernanda Saloum de Neves Manta, Lorena Bruna P. de Oliveira, Pedro Henrique Ferreira Marçal, Euzenir Nunes Sarno, Milton Ozório Moraes, Raúl Marcel González Garcia and Lucia Alves de Oliveira Fraga

    Citation: BMC Infectious Diseases 2018 18:153

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  3. Content type: Research article

    Mycobacterium tuberculosis drug resistance is a major challenge to the use of standardized regimens for tuberculosis (TB) therapy, especially among previously treated patients. We aimed to investigate the frequen...

    Authors: Audrey Forson, Awewura Kwara, Samuel Kudzawu, Michael Omari, Jacob Otu, Florian Gehre, Bouke de Jong and Martin Antonio

    Citation: BMC Infectious Diseases 2018 18:149

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  4. Content type: Research article

    Pretreatment loss to follow-up (PTLFU) is a barrier to tuberculosis (TB) control in India’s Revised National TB Control Programme (RNTCP). PTLFU studies have not been conducted in India’s mega-cities, where pa...

    Authors: Beena E. Thomas, Ramnath Subbaraman, Senthil Sellappan, Chandra Suresh, J. Lavanya, Savari Lincy, Agnes Lawrence Raja, B. Javeed, S. Kokila, S. Arumugam, Soumya Swaminathan and Kenneth H. Mayer

    Citation: BMC Infectious Diseases 2018 18:142

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  5. Content type: Research article

    Since 2006, the Peruvian National TB program (NTP) recommends voluntary counseling and testing (VCT) for all tuberculosis (TB) patients. Responding to the differential burden of both diseases in Peru, TB is ma...

    Authors: Suzanne Ramírez, Fernando Mejía, Marlene Rojas, Carlos Seas, Patrick Van der Stuyft, Eduardo Gotuzzo and Larissa Otero

    Citation: BMC Infectious Diseases 2018 18:136

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  6. Content type: Research article

    Precise designation of high risk forms of latent Mycobacterium tuberculosis-M.tb infections (LTBI) is impossible. Delineation of high-risk LTBI can, however, allow for chemoprophylaxis and curtail majority cases ...

    Authors: Misaki Wayengera, David P. Kateete, Benon Asiimwe and Moses L. Joloba

    Citation: BMC Infectious Diseases 2018 18:133

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  7. Content type: Research article

    Drug resistant tuberculosis (TB) is increasing in prevalence worldwide. Treatment failure and relapse is known to be high for patients with isoniazid resistant TB treated with standard first line regimens. How...

    Authors: Phan Vuong Khac Thai, Dang Thi Minh Ha, Nguyen Thi Hanh, Jeremy Day, Sarah Dunstan, Nguyen Thi Quynh Nhu, Vo Sy Kiet, Nguyen Huu Lan, Nguyen Huy Dung, Nguyen Thi Ngoc Lan, Nguyen Thuong Thuong, Nguyen Ngoc Lan, Phạm Thị Thúy Liễu, Nguyễn Thị Hồng, Đào Công Điệp, Nguyễn Thị Kim Thanh…

    Citation: BMC Infectious Diseases 2018 18:112

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  8. Content type: Research article

    Tuberculosis (TB) contact tracing is a key strategy for containing TB and provides addition to the passive case finding approach. However, this practice has not been implemented in Tanzania, where there is una...

    Authors: Medard Beyanga, Benson R. Kidenya, Lisa Gerwing-Adima, Eleanor Ochodo, Stephen E. Mshana and Christa Kasang

    Citation: BMC Infectious Diseases 2018 18:110

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  9. Content type: Research article

    Few prospective cohort studies, none in China, have investigated the relationship between treatment outcomes of multidrug-resistant tuberculosis (MDR-TB) patients and sputum culture conversion. Factors affecti...

    Authors: Qiao Liu, Peng Lu, Leonardo Martinez, Haitao Yang, Wei Lu, Xiaoyan Ding and Limei Zhu

    Citation: BMC Infectious Diseases 2018 18:114

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  10. Content type: Research article

    Monitoring the treatment outcomes of tuberculosis and determining the specific factors associated with unsuccessful treatment outcome are essential to evaluate the effectiveness of tuberculosis control program...

    Authors: Yufeng Wen, Zhiping Zhang, Xianxiang Li, Dan Xia, Jun Ma, Yuanyuan Dong and Xinwei Zhang

    Citation: BMC Infectious Diseases 2018 18:104

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  11. Content type: Research article

    In 2012, the World Health Organization launched guidelines for systematically investigating contacts of persons with infectious tuberculosis (TB) in low- and middle-income countries. As such, it is necessary t...

    Authors: Gladys Kigozi, Michelle Engelbrecht, Christo Heunis and André Janse van Rensburg

    Citation: BMC Infectious Diseases 2018 18:106

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  12. Content type: Case report

    Mycobacterium tuberculosis (M. tuberculosis) disease is a generally well-known problem among immunocompromised adults and children. In pediatric oncology, only few cases of M. tuberculosis disease are reported so...

    Authors: Karoline van de Loo, Stefan Balzer, Colin R. MacKenzie, Thomas M. Boemers, Monika Ortmann, Jörg Schaper, Arndt Borkhardt, Hans-Jürgen Laws and Michaela Kuhlen

    Citation: BMC Infectious Diseases 2018 18:105

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  13. Content type: Research article

    Growth-based drug susceptibility testing (DST) is the reference standard for diagnosing drug-resistant tuberculosis (TB), but standard time to result (TTR) is typically ≥ 3 weeks. Rapid tests can reduce that T...

    Authors: Erik J. Groessl, Theodore G. Ganiats, Naomi Hillery, Andre Trollip, Roberta L. Jackson, Donald G. Catanzaro, Timothy C. Rodwell, Richard S. Garfein, Camilla Rodrigues, Valeriu Crudu, Thomas C. Victor and Antonino Catanzaro

    Citation: BMC Infectious Diseases 2018 18:102

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  14. Content type: Research article

    The emergence of extensively drug-resistant tuberculosis (XDR-TB) has raised public health concern for global TB control. Although multi drug-resistant tuberculosis (MDR- TB) prevalence and associated genetic ...

    Authors: Amal Oudghiri, Hind Karimi, Fouad Chetioui, Fathiah Zakham, Jamal Eddine Bourkadi, My Driss Elmessaoudi, Amin Laglaoui, Imane Chaoui and Mohammed El Mzibri

    Citation: BMC Infectious Diseases 2018 18:98

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  15. Content type: Research article

    Tuberculosis (TB) recurrence represents a challenge to control programs. In low incidence countries, the prevailing risk factors leading to recurrence are poorly characterised.

    Authors: Andrew Rosser, Matthew Richardson, Martin J. Wiselka, Robert C. Free, Gerrit Woltmann, Galina V. Mukamolova and Manish Pareek

    Citation: BMC Infectious Diseases 2018 18:94

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  16. Content type: Research article

    Smear microscopy lacks sensitivity especially in HIV co-infection, resulting in undiagnosed tuberculosis (TB) and high mortality. The loop-mediated isothermal amplification (TB-LAMP) assay can be staged with m...

    Authors: Lydia Nakiyingi, Prossy Nakanwagi, Jessica Briggs, Tifu Agaba, Frank Mubiru, Mark Mugenyi, Willy Ssengooba, Moses L. Joloba and Yukari C. Manabe

    Citation: BMC Infectious Diseases 2018 18:87

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  17. Content type: Research article

    Tuberculosis (TB) transmission is influenced by patient-related risk, environment and bacteriological factors. We determined the risk factors associated with cluster size of IS6110 RFLP based genotypes of Mycobac...

    Authors: Renata Lyrio Peres, Solange Alves Vinhas, Fabíola Karla Correa Ribeiro, Moisés Palaci, Thiago Nascimento do Prado, Bárbara Reis-Santos, Eliana Zandonade, Philip Noel Suffys, Jonathan E. Golub, Lee W. Riley and Ethel Leonor Maciel

    Citation: BMC Infectious Diseases 2018 18:71

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  18. Content type: Case report

    Although atypical mycobacteria had been increasingly found in various ocular infections in the past decades, a slow-growing Mycobacterium haemophilum (M. haemophilum) was scarcely reported. Similar to tuberculous...

    Authors: Warinyupa Pinitpuwadol, Sucheera Sarunket, Sutasinee Boonsopon, Nattaporn Tesavibul and Pitipol Choopong

    Citation: BMC Infectious Diseases 2018 18:70

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