Tuberculosis and other mycobacterial diseases

Section edited by Edward Graviss, Eyal Oren & Anna Vassall

This section aims to publish studies looking at all aspects of of the prevention, diagnosis and management of tuberculosis and other mycobacterial diseases in humans, including HIV-associated tuberculosis, as well as related molecular genetics, pathophysiology, and epidemiology.

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  1. Research article

    Immunological recovery in tuberculosis/HIV co-infected patients on antiretroviral therapy: implication for tuberculosis preventive therapy

    Understanding the immune response to combination antiretroviral therapy (cART) is essential for a clear approach to tuberculosis (TB) preventive therapy. We investigated the immunological recovery in cART-trea...

    Basel Karo, Gérard Krause, Stefanie Castell, Christian Kollan, Osamah Hamouda and Walter Haas

    BMC Infectious Diseases 2017 17:517

    Published on: 25 July 2017

  2. Research article

    Validity and reliability of the tuberculosis-related stigma scale version for Brazilian Portuguese

    Stigma associated with tuberculosis (TB) has been an object of interest in several regions of the world. The behaviour presented by patients as a result of social discrimination has contributed to delays in di...

    Juliane de Almeida Crispim, Laís Mara Caetano da Silva, Mellina Yamamura, Marcela Paschoal Popolin, Antônio Carlos Vieira Ramos, Luiz Henrique Arroyo, Ana Angélica Rêgo de Queiroz, Aylana de Souza Belchior, Danielle Talita dos Santos, Flávia Meneguetti Pieri, Ludmila Barbosa Bandeira Rodrigues, Simone Terezinha Protti, Ione Carvalho Pinto, Pedro Fredemir Palha and Ricardo Alexandre Arcêncio

    BMC Infectious Diseases 2017 17:510

    Published on: 21 July 2017

  3. Research article

    Pyrazinamide resistance-conferring mutations in pncA and the transmission of multidrug resistant TB in Georgia

    The ongoing epidemic of multidrug-resistant tuberculosis (MDR-TB) in Georgia highlights the need for more effective control strategies. A new regimen to treat MDR-TB that includes pyrazinamide (PZA) is current...

    Sarah Sengstake, Indra L Bergval, Anja R Schuitema, Jessica L de Beer, Jody Phelan, Rina de Zwaan, Taane G Clark, Dick van Soolingen and Richard M Anthony

    BMC Infectious Diseases 2017 17:491

    Published on: 12 July 2017

  4. Research article

    Evaluation of the relationship between MARCO and CD36 single-nucleotide polymorphisms and susceptibility to pulmonary tuberculosis in a Chinese Han population

    Gene polymorphisms impact greatly on a person’s susceptibility to pulmonary tuberculosis (PTB). Macrophage receptor with collagenous structure (MARCO) and CD36 are two scavenger receptors (SRs) that can recogn...

    Wenting Lao, Hui Kang, Guojiang Jin, Li Chen, Yang Chu, Jiao Sun and Bingqi Sun

    BMC Infectious Diseases 2017 17:488

    Published on: 11 July 2017

  5. Research article

    Treatment delay and fatal outcomes of pulmonary tuberculosis in advanced age: a retrospective nationwide cohort study

    Studies focusing on pulmonary tuberculosis in advanced age (≥80 years) are lacking. This study aimed to explore treatment delay, outcomes and their predictors in this group.

    Chih-Hsin Lee, Jann-Yuan Wang, Hsien-Chun Lin, Pai-Yang Lin, Jer-Hwa Chang, Chi-Won Suk, Li-Na Lee, Chou-Chin Lan and Kuan-Jen Bai

    BMC Infectious Diseases 2017 17:449

    Published on: 24 June 2017

  6. Research article

    Development and validation of a prognostic scoring model for Mycobacterium avium complex lung disease: an observational cohort study

    Patients with Mycobacterium avium complex (MAC) lung disease (LD) have a heterogeneous prognosis. This study aimed to develop and validate a prognostic scoring model for these patients using independent risk fact...

    Shogo Kumagai, Akihiro Ito, Toru Hashimoto, Satoshi Marumo, Hironobu Tokumasu, Aya Kotani, Haruka Yamaki, Masahiro Shirata, Koji Furuuchi, Motonari Fukui and Tadashi Ishida

    BMC Infectious Diseases 2017 17:436

    Published on: 19 June 2017

  7. Study protocol

    Efficacy of ultra-short course chemotherapy for new smear positive drug susceptible pulmonary tuberculosis: study protocol of a multicenter randomized controlled clinical trial

    Shortening the standard 6-month treatment for drug-susceptible pulmonary tuberculosis (DS-PTB) would be a major improvement for TB case management and disease control.

    Mengqiu Gao, Jingtao Gao, Jian Du, Yuhong Liu, Yao Zhang, Liping Ma, Fengling Mi, Liang Li and Shenjie Tang

    BMC Infectious Diseases 2017 17:435

    Published on: 19 June 2017

  8. Research article

    Using genotyping to delineate tuberculosis transmission in long-term care facilities: single facility 4-year experience

    Residents in long-term care facilities (LTCFs) are vulnerable to tuberculosis (TB) transmission; however, to delineate possible routes of TB transmission in LTCFs is difficult. This study aimed to address the ...

    Wen-Cheng Chao, Pei-Chun Chuang, Don-Han Wu, Chieh-Liang Wu, Po-Yu Liu, Chi-Chang Shieh and Ruwen Jou

    BMC Infectious Diseases 2017 17:421

    Published on: 13 June 2017

  9. Case report

    Peripheral neuropathy in a diabetic child treated with linezolid for multidrug-resistant tuberculosis: a case report and review of the literature

    Extensively drug-resistant (XDR) tuberculosis (TB) and multidrug resistant (MDR)-TB with additional resistance to injectable agents or fluoroquinolones are challenging to treat due to lack of available, effect...

    Aravind Swaminathan, Philipp du Cros, James A. Seddon, Shamsiya Mirgayosieva, Rajabov Asladdin and Zulfiya Dusmatova

    BMC Infectious Diseases 2017 17:417

    Published on: 12 June 2017

  10. Research article

    Diagnostic accuracy of nucleic acid amplification tests (NAATs) in urine for genitourinary tuberculosis: a systematic review and meta-analysis

    Genitourinary tuberculosis is the third most common form of extrapulmonary tuberculosis. Diagnosis is difficult because of unspecific clinical manifestations and low accuracy of conventional tests. Unfortunate...

    Carlos Altez-Fernandez, Victor Ortiz, Majid Mirzazadeh, Luis Zegarra, Carlos Seas and Cesar Ugarte-Gil

    BMC Infectious Diseases 2017 17:390

    Published on: 5 June 2017

  11. Research article

    Tuberculosis screening among persons with diabetes mellitus in Pune, India

    Diabetes mellitus (DM) increases tuberculosis (TB) risk, and there is increasing concern over the public health implications of the convergence of these two epidemics. Screening for TB among people with DM is ...

    Vidya Mave, Smita Nimkar, Haridas Prasad, Dileep Kadam, Sushant Meshram, Rahul Lokhande, Nikhil Gupte, Divyashri Jain, Amita Gupta and Jonathan E. Golub

    BMC Infectious Diseases 2017 17:388

    Published on: 2 June 2017

  12. Research article

    Diagnostic accuracy and usefulness of the Genotype MTBDRplus assay in diagnosing multidrug-resistant tuberculosis in Cameroon: a cross-sectional study

    Drug-resistant tuberculosis, especially multidrug-resistant tuberculosis (MDR-TB), is a major public health problem. Effective management of MDR-TB relies on accurate and rapid diagnosis. In this study, we ass...

    Ngu Njei Abanda, Josiane Yvonne Djieugoué, Eunjung Lim, Eric Walter Pefura-Yone, Wilfred Fon Mbacham, Guy Vernet, Veronique Mbeng Penlap, Sara Irene Eyangoh, Diane Wallace Taylor and Rose Gana Fomban Leke

    BMC Infectious Diseases 2017 17:379

    Published on: 31 May 2017

  13. Correspondence

    A user-friendly mathematical modelling web interface to assist local decision making in the fight against drug-resistant tuberculosis

    Multidrug-resistant and rifampicin-resistant tuberculosis (MDR/RR-TB) represent an important challenge for global tuberculosis (TB) control. The high rates of MDR/RR-TB observed among re-treatment cases can ar...

    Romain Ragonnet, James M. Trauer, Justin T. Denholm, Ben J. Marais and Emma S. McBryde

    BMC Infectious Diseases 2017 17:374

    Published on: 30 May 2017

  14. Research article

    Genetic diversity of Mycobacterium tuberculosis isolates from Tochigi prefecture, a local region of Japan

    Foreign-born patients with tuberculosis (TB) may introduce globally disseminated isolates of Mycobacterium tuberculosis into large cities in Japan. The risk of dissemination of these isolates into local regions, ...

    Fuminori Mizukoshi, Tohru Miyoshi-Akiyama, Hiroki Iwai, Takako Suzuki, Reiko Kiritani, Teruo Kirikae and Keiji Funatogawa

    BMC Infectious Diseases 2017 17:365

    Published on: 25 May 2017

  15. Research article

    Comparison of antibody responses against Mycobacterium tuberculosis antigen Rv0679c in tuberculosis patients from the endemic and non-endemic regions of the Beijing genotype: a case control study

    Strains of the Beijing genotype of Mycobacterium tuberculosis (MTB) are reportedly associated with the virulence of tuberculosis (TB) infection, unfavorable outcomes of anti-TB treatment, and the global TB pandem...

    Jingge Zhao, Takashi Matsuba, Xiaoyan Zhang, Susan Leano, Chie Nakajima, Haorile Chagan-Yasutan, Elizabeth Freda Telan, Yasuhiko Suzuki and Toshio Hattori

    BMC Infectious Diseases 2017 17:344

    Published on: 15 May 2017

  16. Research article

    Early morning urine collection to improve urinary lateral flow LAM assay sensitivity in hospitalised patients with HIV-TB co-infection

    Urine LAM testing has been approved by the WHO for use in hospitalised patients with advanced immunosuppression. However, sensitivity remains suboptimal. We therefore examined the incremental diagnostic sensit...

    Phindile Gina, Philippa J. Randall, Tapuwa E. Muchinga, Anil Pooran, Richard Meldau, Jonny G. Peter and Keertan Dheda

    BMC Infectious Diseases 2017 17:339

    Published on: 12 May 2017

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