Sexually transmitted diseases

Section edited by Stefan Baral & Joseph Tucker

This section aims to publish studies looking at all aspects of of the prevention, diagnosis and management of sexually transmitted diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. HIV and HIV-associated infections are considered in a separate section.

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  1. Research article

    Effects on preventing mother-to-child transmission of syphilis and associated adverse pregnant outcomes: a longitudinal study from 2001 to 2015 in Shanghai, China

    Maternal syphilis is a health threat to both the pregnant women and the children. This study aimed to delineate the longitudinal trend of maternal syphilis and burden of associated adverse pregnant outcomes (A...

    Yang Li, Liping Zhu, Li Du, Lingxiao Qu, Weili Jiang and Biao Xu

    BMC Infectious Diseases 2017 17:626

    Published on: 18 September 2017

  2. Research article

    Factors associated with syphilis treatment failure and reinfection: a longitudinal cohort study in Shenzhen, China

    The treatment failure and reinfection rates among syphilis patients are high, and relevant studies in China are limited. The aim of this study was to detect the rates of treatment failure and reinfection after...

    Zhenzhou Luo, Lin Zhu, Yi Ding, Jun Yuan, Wu Li, Qiuhong Wu, Lishan Tian, Li Zhang, Guomao Zhou, Tao Zhang, Jianping Ma, Zhongwei Chen, Tubao Yang, Tiejian Feng and Min Zhang

    BMC Infectious Diseases 2017 17:620

    Published on: 13 September 2017

  3. Research article

    Overall Low Extended-Spectrum Cephalosporin Resistance but high Azithromycin Resistance in Neisseria gonorrhoeae in 24 European Countries, 2015

    Surveillance of Neisseria gonorrhoeae antimicrobial susceptibility in Europe is performed through the European Gonococcal Antimicrobial Surveillance Programme (Euro-GASP), which additionally provides data to info...

    Michelle J. Cole, Gianfranco Spiteri, Susanne Jacobsson, Neil Woodford, Francesco Tripodo, Andrew J. Amato-Gauci and Magnus Unemo

    BMC Infectious Diseases 2017 17:617

    Published on: 11 September 2017

  4. Research article

    Clinical care given to victims of sexual assault at Kadoma General Hospital, Zimbabwe: a secondary data analysis, 2016

    Despite the guidelines for managing sexual assault being in place, victims of sexual assault attended to at Kadoma General Hospital consistently raised complaints related to the quality of care offered. Medico...

    Stanley Tapesana, Daniel Chirundu, Gerald Shambira, Notion Tafara Gombe, Tsitsi Patience Juru and Tshimanga Mufuta

    BMC Infectious Diseases 2017 17:602

    Published on: 31 August 2017

  5. Research article

    Seroprevalence of Herpes Simplex Virus type-2 (HSV-2) among pregnant women who participated in a national HIV surveillance activity in Haiti

    Herpes simplex virus type 2 (HSV-2), one the most common causes of genital ulcers, appears to increase both the risk of HIV acquisition and HIV transmission. HSV-2/HIV co-infection among pregnant women may inc...

    Jean Wysler Domercant, Frantz Jean Louis, Erin Hulland, Mark Griswold, Jocelyne Andre-Alboth, Tun Ye and Barbara J. Marston

    BMC Infectious Diseases 2017 17:577

    Published on: 18 August 2017

  6. Research article

    Retesting and repeat positivity following diagnosis of Chlamydia trachomatis and Neisseria gonorrhoea in New Zealand: a retrospective cohort study

    Testing for reinfection at 3 to 6 months following treatment for Chlamydia Trachomatis or Neisseria gonorrhoea is recommended in best practice sexual health management guidelines. This study aimed to describe rat...

    Sally B. Rose, Susan M. Garrett, James Stanley and Susan R. H. Pullon

    BMC Infectious Diseases 2017 17:526

    Published on: 28 July 2017

  7. Case report

    A case report of CT-diagnosed renal infarct secondary to syphilitic aortitis

    Even though reported cases of syphilis have been increasing, cases of tertiary syphilis remain extremely rare. The majority of our knowledge with regard to complications of syphilis such as aortitis was acquir...

    Maaike Spaltenstein, Françoise Humbert, Diem-Lan Vu, Ilker Uçkay and Gregor John

    BMC Infectious Diseases 2017 17:520

    Published on: 26 July 2017

  8. Case report

    Tertiary syphilis in the lumbar spine: a case report

    The incidence of tertiary syphilis involvement in the spinal column with destructive bone lesions is very rare. It is difficult to establish the correct diagnosis from radiographs and histological examination ...

    Yang Bai, Feng Niu, Lidi Liu, Hui Sha, Yimei Wang and Song Zhao

    BMC Infectious Diseases 2017 17:513

    Published on: 24 July 2017

  9. Research article

    Decreasing seroprevalence of herpes simplex virus type 1 and type 2 in Germany leaves many people susceptible to genital infection: time to raise awareness and enhance control

    Herpes simplex infections (HSV1/2) are characterized by recurrent symptoms, a risk of neonatal herpes, and the facilitation of HIV transmission. In Germany, HSV1/2 infections are not notifiable and data are sc...

    Gerit Korr, Michael Thamm, Irina Czogiel, Christina Poethko-Mueller, Viviane Bremer and Klaus Jansen

    BMC Infectious Diseases 2017 17:471

    Published on: 6 July 2017

  10. Study protocol

    A multicentre double-blind randomised controlled trial evaluating the efficacy of daily use of antibacterial mouthwash against oropharyngeal gonorrhoea among men who have sex with men: the OMEGA (Oral Mouthwash use to Eradicate GonorrhoeA) study protocol

    Gonorrhoea is one of the most common sexually transmissible infections in men who have sex with men (MSM). Gonorrhoea rates have increased substantially in recent years. There is concern that increasing gonorr...

    Eric P. F. Chow, Sandra Walker, Jane S. Hocking, Catriona S. Bradshaw, Marcus Y. Chen, Sepehr N. Tabrizi, Benjamin P. Howden, Matthew G. Law, Kate Maddaford, Tim R. H. Read, David A. Lewis, David M. Whiley, Lei Zhang, Andrew E. Grulich, John M. Kaldor, Vincent J. Cornelisse…

    BMC Infectious Diseases 2017 17:456

    Published on: 28 June 2017

  11. Study protocol

    Comparing self- and provider-collected swabbing for HPV DNA testing in female-to-male transgender adult patients: a mixed-methods biobehavioral study protocol

    Cervical cancer, nearly all cases of which are caused by one of several high-risk strains of the human papillomavirus (hr-HPV), leads to significant morbidity and mortality in individuals with a cervix. Trans ...

    Sari L. Reisner, Madeline B. Deutsch, Sarah M. Peitzmeier, Jaclyn M. White Hughto, Timothy Cavanaugh, Dana J. Pardee, Sarah McLean, Elliot J. Marrow, Matthew J. Mimiaga, Lori Panther, Marcy Gelman, Jamison Green and Jennifer Potter

    BMC Infectious Diseases 2017 17:444

    Published on: 23 June 2017

  12. Research article

    Clinical characteristics of acute hepatitis A outbreak in Taiwan, 2015–2016: observations from a tertiary medical center

    Acute hepatitis A is a fecal-oral transmitted disease related to inadequate sanitary conditions. In addition to its traditional classification, several outbreaks in the men who have sex with men (MSM) populati...

    Nan-Yu Chen, Zhuo-Hao Liu, Shian-Sen Shie, Tsung-Hsing Chen and Ting-Shu Wu

    BMC Infectious Diseases 2017 17:441

    Published on: 20 June 2017

  13. Study protocol

    Design of a syndemic based intervention to facilitate care for men who have sex with men with high risk behaviour: the randomized controlled trial

    Men who have sex with men (MSM) constitute a risk group for sexual transmitted infections (STIs), including HIV. Despite counselling interventions, risk behaviour remains high. Syndemic theory holds that psych...

    Roel C. A. Achterbergh, Jannie J. van der Helm, Wim van den Brink and Henry J. C. de Vries

    BMC Infectious Diseases 2017 17:398

    Published on: 6 June 2017

  14. Research article

    Prevalence and distribution of Gardnerella vaginalis subgroups in women with and without bacterial vaginosis

    Bacterial vaginosis (BV) is one of the leading causes of vaginal complaints among women of childbearing age. The role of Gardnerella vaginalis remains controversial due to its presence in healthy and BV-type vagi...

    Migle Janulaitiene, Virginija Paliulyte, Svitrigaile Grinceviciene, Jolita Zakareviciene, Alma Vladisauskiene, Agne Marcinkute and Milda Pleckaityte

    BMC Infectious Diseases 2017 17:394

    Published on: 5 June 2017

  15. Research article

    Analysis of epidemiological trends in human papillomavirus infection among gynaecological outpatients in Hangzhou, China, 2011–2015

    HPV infection is the major pathogenic factor underlying cervical cancer and precancerous lesions. The cervical HPV infection rates in gynaecological outpatients from Hangzhou, China, were studied in the period...

    Lili Qian, Yu Zhang, Dawei Cui, Bin Lou, Yimin Chen, Ying Yu, Yonglin Liu and Yu Chen

    BMC Infectious Diseases 2017 17:393

    Published on: 5 June 2017

  16. Research article

    Independent prognostic role of human papillomavirus genotype in cervical cancer

    Although the correlation of HPV genotype with cervical precursor lesions and invasive cancer has been confirmed, the role of HPV genotype in cervical cancer prognosis is less conclusive. This study aims to sys...

    Dong Hang, Meiqun Jia, Hongxia Ma, Jing Zhou, Xiaoshuang Feng, Zhangyan Lyu, Jian Yin, Hong Cui, Yin Yin, Guangfu Jin, Zhibin Hu, Hongbing Shen, Kai Zhang, Ni Li and Min Dai

    BMC Infectious Diseases 2017 17:391

    Published on: 5 June 2017

  17. Research article

    Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from Hefei (2014–2015): genetic characteristics of antimicrobial resistance

    Antimicrobial resistance (AMR) and genetic determinants of resistance of N. gonorrhoeae isolates from Hefei, China, were characterized adding a breadth of information to the molecular epidemiology of gonococcal r...

    Fa-Xing Jiang, Qian Lan, Wen-Jing Le and Xiao-Hong Su

    BMC Infectious Diseases 2017 17:366

    Published on: 25 May 2017

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