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Parasitological diseases

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of parasitological diseases in humans, as well as related studies on molecular and cellular biology, pathophysiology, and epidemiology.

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  1. Skin ulcers in American cutaneous leishmaniasis (ACL) may heal spontaneously after months/years. However, few cases may present quick heal even during diagnosis procedure (early spontaneous healing- ESH). The ...

    Authors: Carla Oliveira-Ribeiro, Maria Inês Fernandes Pimentel, Raquel de Vasconcellos Carvalhaes Oliveira, Aline Fagundes, Maria de Fatima Madeira, Cintia Xavier Mello, Eliame Mouta-Confort, Claudia Maria Valete-Rosalino, Erica de Camargo Ferreira Vasconcellos, Marcelo Rosandiski Lyra, Leonardo Pereira Quintella, Liliane de Fatima Antonio, Armando Schubach and Fatima Conceição-Silva

    Citation: BMC Infectious Diseases 2017 17:559

    Content type: Research article

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  2. Leishmaniasis and melioidosis are frequently reported from the North Central Province of Sri Lanka. However, only one case of co-infection of the two diseases has been reported to date over the world. This is ...

    Authors: Isuru Chamika Indeewara Kahandawaarachchi, Gayani Samadara Premawansa, Wipula Warnasuriya, Malka Dassanayake and Enoka Corea

    Citation: BMC Infectious Diseases 2017 17:533

    Content type: Case report

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  3. Primary amoebic meningoencephalitis (PAM) is a fulminant disease of the brain caused by Naegleria fowleri. Although the disease is rare, the case fatality rate is very high. In this report, we describe the first ...

    Authors: Mashina Chomba, Luchenga A. Mucheleng’anga, Sombo Fwoloshi, Joseph Ngulube and Mable M. Mutengo

    Citation: BMC Infectious Diseases 2017 17:532

    Content type: Case report

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  4. Hepatic iron overload has been implicated in many liver diseases; however, whether it is involved in clonorchiasis remains unknown. The purpose of this study is to investigate whether Clonorchis sinensis (C. sine...

    Authors: Su Han, Qiaoran Tang, Rui Chen, Yihong Li, Jing Shu and Xiaoli Zhang

    Citation: BMC Infectious Diseases 2017 17:531

    Content type: Research article

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  5. Anisakiasis is a fish-borne zoonosis caused by Anisakis spp. larvae. One challenging issue in the diagnosis of anisakiasis is the molecular detection of the etiological agent even at very low quantity, such as in...

    Authors: Simonetta Mattiucci, Michela Paoletti, Alessandra Colantoni, Antonella Carbone, Raffaele Gaeta, Agnese Proietti, Stefano Frattaroli, Paolo Fazii, Fabrizio Bruschi and Giuseppe Nascetti

    Citation: BMC Infectious Diseases 2017 17:530

    Content type: Technical advance

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  6. In the wake of a decline in global malaria, it is imperative to describe the epidemiology of malaria in a country to inform control policies. The purpose of this study was to describe the epidemiological and c...

    Authors: Tebit Emmanuel Kwenti, Tayong Dizzle Bita Kwenti, Andreas Latz, Longdoh Anna Njunda and Theresa Nkuo-Akenji

    Citation: BMC Infectious Diseases 2017 17:499

    Content type: Research article

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  7. Schistosomiasis is a disease of public health importance with long term complications mostly common among children, rural dwellers, poor and migrant workers. Studies have not documented the burden among migran...

    Authors: Obioma Uchendu, Victoria Oladoyin, Michael Idowu, Oluwapelumi Adeyera, Oluwatosin Olabisi, Oluwafisayomi Oluwatosin and Gbemisola Leigh

    Citation: BMC Infectious Diseases 2017 17:487

    Content type: Research article

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  8. Giardia is a leading but neglected cause of infectious gastroenteritis worldwide and is treatable. There is a substantial burden of undetected Giardia in the UK and for every one case ...

    Authors: Alison Waldram, Roberto Vivancos, Catherine Hartley and Kenneth Lamden

    Citation: BMC Infectious Diseases 2017 17:486

    Content type: Research article

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  9. Toxoplasmosis is one of the common worldwide parasitic zoonosis due to Toxoplasma gondii (T. gondii). Toxoplasmosis during pregnancy can result in fetal and neonatal death or various congenital defects. The aim o...

    Authors: Sanata Bamba, Mamoudou Cissé, Ibrahim Sangaré, Adama Zida, Souleymane Ouattara and Robert T. Guiguemdé

    Citation: BMC Infectious Diseases 2017 17:482

    Content type: Research article

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  10. Leishmaniasis is a protozoan disease caused by parasites of the genus Leishmania, transmitted to humans by sandflies. The diagnosis of leishmaniasis is often challenging as it mimics many other infectious or mali...

    Authors: Gilles Darcis, Gert Van der Auwera, Jean-Baptiste Giot, Marie-Pierre Hayette, Françoise Tassin, Jorge Arrese Estrada, Lieselotte Cnops, Michel Moutschen, Laurence de Leval and Philippe Leonard

    Citation: BMC Infectious Diseases 2017 17:478

    Content type: Case report

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  11. We present one unusual case of anophthalmia and craniofacial cleft, probably due to congenital toxoplasmosis only.

    Authors: Gabriel Emmanuel Arce-Estrada, Valeria Gómez-Toscano, Carlos Cedillo-Peláez, Ana Luisa Sesman-Bernal, Vanessa Bosch-Canto, José Luis Mayorga-Butrón, José Antonio Vargas-Villavicencio and Dolores Correa

    Citation: BMC Infectious Diseases 2017 17:459

    Content type: Case report

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  12. The neglected zoonotic diseases (NZD) are an understudied group that are a major cause of illness throughout the developing world. In general, little is known about the prevalence and burden of NZDs in affecte...

    Authors: Eric M. Fèvre, William A. de Glanville, Lian F. Thomas, Elizabeth A. J. Cook, Samuel Kariuki and Claire N. Wamae

    Citation: BMC Infectious Diseases 2017 17:457

    Content type: Research article

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  13. Cystic echinococcosis (CE) is a chronic, complex and neglected zoonotic disease. CE occurs worldwide. In humans, it may result in a wide spectrum of clinical manifestations, ranging from asymptomatic infection...

    Authors: Virginia Velasco-Tirado, Ángela Romero-Alegría, Moncef Belhassen-García, Montserrat Alonso-Sardón, Carmen Esteban-Velasco, Amparo López-Bernús, Adela Carpio-Perez, Marcelo Fernando Jimenez López, Juan Luis Muñoz Bellido, Antonio Muro, Miguel Cordero-Sanchez, Javier Pardo-Lledias and Luis Muñoz-Bellvis

    Citation: BMC Infectious Diseases 2017 17:455

    Content type: Research article

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  14. Plasmodium falciparum infection can progress unpredictably to severe forms including respiratory distress and cerebral malaria. The mechanisms underlying the variable natural course of...

    Authors: Jean Claude Biteghe Bi Essone, Nadine N’Dilimabaka, Julien Ondzaga, Jean Bernard Lekana-Douki, Dieudonné Nkoghe Mba, Philippe Deloron, Dominique Mazier, Frédrérick Gay and Fousseyni S. Touré Ndouo

    Citation: BMC Infectious Diseases 2017 17:454

    Content type: Research article

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  15. Anaemia is common in malaria. It is important to quantitate the risk of anaemia and to distinguish factors related to the natural history of disease from potential drug toxicity.

    Authors: Julien Zwang, Umberto D’Alessandro, Jean-Louis Ndiaye, Abdoulaye A Djimdé, Grant Dorsey, Andreas A Mårtensson, Corine Karema and Piero L. Olliaro

    Citation: BMC Infectious Diseases 2017 17:443

    Content type: Research article

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  16. This paper studies the effect of mosquito abundance and malaria incidence in the last 3 weeks, and their interaction, on the hazard of time to malaria in a previously studied cohort of children in Ethiopia.

    Authors: Denekew Bitew Belay, Yehenew Getachew Kifle, Ayele Taye Goshu, Jon Michael Gran, Delenasaw Yewhalaw, Luc Duchateau and Arnoldo Frigessi

    Citation: BMC Infectious Diseases 2017 17:415

    Content type: Research Article

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  17. Rapid diagnostic tests (RDTs) are alternative methods for microscopy in the diagnosis of malaria in resource limited settings. Among commercially available RDTs, CareStart™ Malaria test was found to show relia...

    Authors: Daniel Getacher Feleke, Shambel Tarko and Haftom Hadush

    Citation: BMC Infectious Diseases 2017 17:399

    Content type: Research article

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  18. Anisakis and Pseudoterranova are the main genera involved in human infections caused by nematodes of the Anisakidae family. Species identification is complicated due to the lack of dif...

    Authors: Julie Brunet, Bernard Pesson, Maude Royant, Jean-Philippe Lemoine, Alexander W. Pfaff, Ahmed Abou-Bacar, Hélène Yera, Emilie Fréalle, Jean Dupouy-Camet, Gema Merino-Espinosa, Magdalena Gómez-Mateos, Joaquina Martin-Sanchez and Ermanno Candolfi

    Citation: BMC Infectious Diseases 2017 17:397

    Content type: Case report

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  19. In Vietnam, no systematic prenatal toxoplasmosis screening is in place, and only few studies have assessed the prevalence and importance of this zoonotic parasite infection. In addition, no studies have been c...

    Authors: G. Suzanne A. Smit, Thi Lam Binh Vu, Trung Dung Do, Niko Speybroeck, Brecht Devleesschauwer, Elizaveta Padalko, Ellen Roets and Pierre Dorny

    Citation: BMC Infectious Diseases 2017 17:364

    Content type: Study protocol

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  20. Intestinal parasitic infections are still one of the major health concerns in developing countries. Monitoring of intestinal parasitic infection and associated risk factors are essential for intervention strat...

    Authors: Tamirat Hailegebriel

    Citation: BMC Infectious Diseases 2017 17:362

    Content type: Research article

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  21. Strongyloidiasis is a chronic parasitic infection caused by Strongyloides stercoralis. Severe cases such as, hyperinfection syndrome (HS) and disseminated strongyloidiasis (DS), can involve pulmonary manifestatio...

    Authors: Daijiro Nabeya, Shusaku Haranaga, Gretchen Lynn Parrott, Takeshi Kinjo, Saifun Nahar, Teruhisa Tanaka, Tetsuo Hirata, Akira Hokama, Masao Tateyama and Jiro Fujita

    Citation: BMC Infectious Diseases 2017 17:320

    Content type: Research article

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  22. Faint test bands of Paracheck Pf.® are interpreted as malaria positive according to world health organization (WHO) guideline. However if there are conspicuous number of faint test bands, a performance of Para...

    Authors: Ryoko Makuuchi, Sandy Jere, Nobuchika Hasejima, Thoms Chigeda and January Gausi

    Citation: BMC Infectious Diseases 2017 17:317

    Content type: Research article

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  23. Intravascular hemolysis is an intrinsic feature of severe malaria pathophysiology but the pathogenic role of cell-free hemoglobin-mediated oxidative stress in severe malaria associated acute kidney injury (AKI...

    Authors: Katherine Plewes, Hugh W.F. Kingston, Aniruddha Ghose, Richard J. Maude, M. Trent Herdman, Stije J. Leopold, Haruhiko Ishioka, Md. Mahtab Uddin Hasan, Md. Shafiul Haider, Shamsul Alam, Kim A. Piera, Prakaykaew Charunwatthana, Kamolrat Silamut, Tsin W. Yeo, Md. Abul Faiz, Sue J Lee…

    Citation: BMC Infectious Diseases 2017 17:313

    Content type: Research article

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  24. Following its recent certification as malaria-free, imported infections now pose the greatest threat for maintaining this status in Sri Lanka. Imported infections may also introduce species that are uncommon o...

    Authors: Sharmini Gunawardena, Rachel F. Daniels, Thishan C. Yahathugoda, Mirani V. Weerasooriya, Katelyn Durfee, Sarah K. Volkman, Dyann F. Wirth and Nadira D. Karunaweera

    Citation: BMC Infectious Diseases 2017 17:307

    Content type: Case report

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  25. Improved understanding of the molecular mechanisms involved in pediatric severe malarial anemia (SMA) pathogenesis is a crucial step in the design of novel therapeutics. Identification of host genetic suscepti...

    Authors: Elly O. Munde, Evans Raballah, Winnie A. Okeyo, John M. Ong’echa, Douglas J. Perkins and Collins Ouma

    Citation: BMC Infectious Diseases 2017 17:291

    Content type: Research article

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  26. Naturally-acquired immunity to Plasmodium falciparum malaria develops after several episodes of infection. Fc gamma receptors (FcγRs) bind to immunoglobulin G (IgG) antibodies and mediate phagocytosis of opsonize...

    Authors: Elly O. Munde, Winnie A. Okeyo, Evans Raballah, Samuel B. Anyona, Tom Were, John M. Ong’echa, Douglas J. Perkins and Collins Ouma

    Citation: BMC Infectious Diseases 2017 17:289

    Content type: Research article

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  27. Analysis of the stool samples is an essential part of routine diagnostics of the helminthes infections. However, the standard methods such Kato and Kato-Katz utilize only a fraction of the information availabl...

    Authors: Sarantos Kostidis, Daria Kokova, Natalia Dementeva, Irina V. Saltykova, Hye Kyong Kim, Young Hae Choi and Oleg A. Mayboroda

    Citation: BMC Infectious Diseases 2017 17:275

    Content type: Technical advance

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  28. Low-dose primaquine is a key candidate for use in malaria transmission reduction and elimination campaigns such as mass drug administration (MDA). Uncertainty about the therapeutic dose range (TDR) required fo...

    Authors: Daniel Joseph Hayes, Clifford George Banda, Alexandra Chipasula-Teleka and Dianne Janette Terlouw

    Citation: BMC Infectious Diseases 2017 17:254

    Content type: Research article

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  29. While the macrophage polarization is well characterized in helminth infections, the natural heterogeneity of monocytes with multiple cell phenotypes might influence the outcome of neglected diseases, such hook...

    Authors: Lívia Silva Araújo Passos, Pedro Henrique Gazzinelli-Guimarães, Tiago Antônio de Oliveira Mendes, Ana Clara Gazzinelli Guimarães, Denise da Silveira Lemos, Natasha Delaqua Ricci, Ricardo Gonçalves, Daniella Castanheira Bartholomeu, Ricardo Toshio Fujiwara and Lilian Lacerda Bueno

    Citation: BMC Infectious Diseases 2017 17:253

    Content type: Research article

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  30. Schistosomiasis, one of the neglected tropical diseases, is endemic in more than 70 countries. However, the clinical diagnosis of patients with a low degree of infection is an unsolved...

    Authors: Kongzhen Gu, Yuesheng Li, Patrick Driguez, Qingren Zeng, Xinlin Yu, Hui Sun, Liting Cai, Yongkang He, Wenyang Wang and Donald P. McManus

    Citation: BMC Infectious Diseases 2017 17:244

    Content type: Research article

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  31. Leishmaniasis is a spectrum of diseases with great relevance to public health. Conventional diagnostic methods are time consuming, needing trained personnel. A robust, rapid and cost effective diagnostic test ...

    Authors: Sandeep Verma, Ruchi Singh, Vanila Sharma, Ram Avtar Bumb, Narendra Singh Negi, V Ramesh and Poonam Salotra

    Citation: BMC Infectious Diseases 2017 17:223

    Content type: Research article

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  32. Chagas disease is caused by the protozoan Trypanosoma cruzi and is characterized by heart failure and sudden death. Identifying which factors are involved in evolution and treatment response is actually challengi...

    Authors: Héctor Rodríguez-Angulo, Juan Marques, Ivan Mendoza, Marco Villegas, Alfredo Mijares, Núria Gironès and Manuel Fresno

    Citation: BMC Infectious Diseases 2017 17:221

    Content type: Research article

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  33. Very little is known about the link of T. gondii infection and depression. Through an age-, gender-, and month of pregnancy-matched case-control study, we determined the association of T. gondii infection and dep...

    Authors: Cosme Alvarado-Esquivel, Ana Liliana Martínez-Martínez, Luis Francisco Sánchez-Anguiano, Jesús Hernández-Tinoco, Juan Manuel Castillo-Orona, Carlos Salas-Martínez, Antonio Sifuentes-Álvarez, Ada Agustina Sandoval-Carrillo, José M. Salas-Pacheco, Oliver Liesenfeld and Elizabeth Irasema Antuna-Salcido

    Citation: BMC Infectious Diseases 2017 17:190

    Content type: Research article

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  34. Clinical manifestations of cutaneous leishmaniasis (CL) caused by Leishmania (Viannia) range from asymptomatic infection to self-limited, or chronic (non-healing) cutaneous lesions. Given the critical role of the...

    Authors: Angélica Mera-Ramírez, Andrés Castillo, Yenifer Orobio, María Adelaida Gómez and Carolina Gallego-Marin

    Citation: BMC Infectious Diseases 2017 17:177

    Content type: Research article

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  35. Visceral leishmaniasis (VL) is an important and potentially fatal neglected tropical disease. The aim of this study was to investigate hyponatremia and risk factors for death among VL patients.

    Authors: Elizabeth De Francesco Daher, Douglas de Sousa Soares, Sérgio Luiz Arruda Parente Filho, Gdayllon Cavalcante Meneses, Tainá Veras de Sandes Freitas, Tacyano Tavares Leite and Geraldo Bezerra da Silva Junior

    Citation: BMC Infectious Diseases 2017 17:168

    Content type: Research article

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  36. Current diagnostic methods for Schistosoma japonicum infection are insensitive for low-density infections. Therefore, a new diagnostic assay based on recombinase polymerase amplification (RPA) technology was esta...

    Authors: Weiwei Xing, Xinling Yu, Jingtao Feng, Kui Sun, Wenliang Fu, Yuanyuan Wang, Minji Zou, Wenrong Xia, Zhihong Luo, Hongbin He, Yuesheng Li and Donggang Xu

    Citation: BMC Infectious Diseases 2017 17:164

    Content type: Research article

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  37. Early rising asexual parasitaemia (ERAP), initially defined as ‘an increase in the parasite count over the baseline pre-treatment level during the first 24 h of treatment’ of falciparum malaria with artemisini...

    Authors: Akintunde Sowunmi, Kazeem Akano, Adejumoke I. Ayede, Elsie O. Adewoye, Godwin Ntadom, Bayo Fatunmbi, Grace O. Gbotosho, Onikepe A. Folarin and Christian T. Happi

    Citation: BMC Infectious Diseases 2017 17:110

    Content type: Research article

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  38. Neurocysticercosis is endemic in most countries of Central and South America but has rarely been described in the French West Indies. We aimed to better understand the clinical and radiological presentation of...

    Authors: R. Blaizot, B. Melot, K. Schepers, M. Nicolas, S. Gaumond, P. Poullain, L. Belaye, A. Lannuzel and B. Hoen

    Citation: BMC Infectious Diseases 2017 17:106

    Content type: Case report

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  39. Mucocutaneous leishmaniasis (MCL), a protozoan infectious disease, is very rare in Iran despite the endemicity of both cutaneous and visceral forms. It is transmitted by the Phlebotomus sand fly. The lip is consi...

    Authors: Iraj Mohammadpour, Mohammad Hossein Motazedian, Farhad Handjani and Gholam Reza Hatam

    Citation: BMC Infectious Diseases 2017 17:96

    Content type: Case report

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  40. Visceral leishmaniasis (VL) is a protozoan disease, which is responsible for 200.000–400.000 yearly infections worldwide. If left untreated, the fatality rate can be as high as 100% within 2 years. 90% of case...

    Authors: Anna Eichenberger, Annina E. Buechi, Andreas Neumayr, Chistroph Hatz, Andri Rauch, Marc Huguenot, Eva Diamantis-Karamitopoulou and Cornelia Staehelin

    Citation: BMC Infectious Diseases 2017 17:81

    Content type: Case report

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  42. Toxoplasma gondii (T. gondii) is an obligate intracellular protozoan parasite with a broad host range including most warm-blooded animals, including humans. T. gondii surface antigen 1...

    Authors: Yali Han, Aihua Zhou, Gang Lu, Guanghui Zhao, Lin Wang, Jingjing Guo, Pengxia Song, Jian Zhou, Huaiyu Zhou, Hua Cong and Shenyi He

    Citation: BMC Infectious Diseases 2017 17:59

    Content type: Research article

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  43. Bidirectional signalling between the brain and the gastrointestinal tract is regulated at neural, hormonal, and immunological levels. Recent studies have shown that helminth infections can alter the normal gut...

    Authors: Vanina Guernier, Bradley Brennan, Laith Yakob, Gabriel Milinovich, Archie C. A. Clements and Ricardo J. Soares Magalhaes

    Citation: BMC Infectious Diseases 2017 17:58

    Content type: Debate

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  44. Sri Lanka achieved the WHO certificate as a malaria free country in September 2016, thus monitoring of malaria transmission using sensitive and effective tools is an important need. Use of age-specific antibod...

    Authors: Rajika Lasanthi Dewasurendra, Janaka Nandana Dias, Nuno Sepulveda, Geethika Sharmini Abayaweera Gunawardena, Naduviladath Chandrasekharan, Chris Drakeley and Nadira Dharshani Karunaweera

    Citation: BMC Infectious Diseases 2017 17:49

    Content type: Research article

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  45. Toxoplasmosis is a neglected zoonotic disease which is prevalent among pregnant women especially in Africa. This study aimed to determine the seroprevalence and determinants of the disease among pregnant women...

    Authors: Christiana Frimpong, Mpundu Makasa, Lungowe Sitali and Charles Michelo

    Citation: BMC Infectious Diseases 2017 17:10

    Content type: Research article

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  46. Prevalence studies report Taenia solium cysticercosis in pig and human populations in Uganda. However, the factors influencing occurrence in smallholder pig production systems are not well documented and little i...

    Authors: Joseph M. Kungu, Michel M. Dione, Francis Ejobi, Michael Ocaido and Delia Grace

    Citation: BMC Infectious Diseases 2017 17:1

    Content type: Research article

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  47. Amoebic liver abscess is the most common extra intestinal manifestation of amoebiasis in tropical countries. It usually presents with right hypochondrial pain, fever and anorexia. Amoebic liver abscess has gai...

    Authors: Vithiya Ratnasamy, Kumanan Thirunavukarasu, Kannathasan Selvam and Murugananthan Arumugam

    Citation: BMC Infectious Diseases 2016 16:741

    Content type: Case report

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  48. Clonorchiasis remains an important zoonotic parasitic disease worldwide. The molecular mechanisms of host-parasite interaction are not fully understood. Non-coding microRNAs (miRNAs) are considered to be key r...

    Authors: Su Han, Qiaoran Tang, Xi Lu, Rui Chen, Yihong Li, Jing Shu, Xiaoli Zhang and Jianping Cao

    Citation: BMC Infectious Diseases 2016 16:724

    Content type: Research article

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  49. Parasitic infections are still a significant health problem in rural areas in developing countries including Iran. There is no recent population-based data about the prevalence of human intestinal parasites in...

    Authors: Bahador Sarkari, Ghasem Hosseini, Mohammad Hossein Motazedian, Mohammad Fararouei and Abdolali Moshfe

    Citation: BMC Infectious Diseases 2016 16:703

    Content type: Research article

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