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Parasitological diseases

Section edited by Honorine Ward & Laith Yakob 

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of parasitological diseases in humans, as well as related studies on molecular and cellular biology, pathophysiology, and epidemiology.

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  1. Content type: Research article

    Improved understanding of the molecular mechanisms involved in pediatric severe malarial anemia (SMA) pathogenesis is a crucial step in the design of novel therapeutics. Identification of host genetic suscepti...

    Authors: Elly O. Munde, Evans Raballah, Winnie A. Okeyo, John M. Ong’echa, Douglas J. Perkins and Collins Ouma

    Citation: BMC Infectious Diseases 2017 17:291

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  2. Content type: Technical advance

    Analysis of the stool samples is an essential part of routine diagnostics of the helminthes infections. However, the standard methods such Kato and Kato-Katz utilize only a fraction of the information availabl...

    Authors: Sarantos Kostidis, Daria Kokova, Natalia Dementeva, Irina V. Saltykova, Hye Kyong Kim, Young Hae Choi and Oleg A. Mayboroda

    Citation: BMC Infectious Diseases 2017 17:275

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  3. Content type: Research article

    While the macrophage polarization is well characterized in helminth infections, the natural heterogeneity of monocytes with multiple cell phenotypes might influence the outcome of neglected diseases, such hook...

    Authors: Lívia Silva Araújo Passos, Pedro Henrique Gazzinelli-Guimarães, Tiago Antônio de Oliveira Mendes, Ana Clara Gazzinelli Guimarães, Denise da Silveira Lemos, Natasha Delaqua Ricci, Ricardo Gonçalves, Daniella Castanheira Bartholomeu, Ricardo Toshio Fujiwara and Lilian Lacerda Bueno

    Citation: BMC Infectious Diseases 2017 17:253

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  4. Content type: Research article

    Low-dose primaquine is a key candidate for use in malaria transmission reduction and elimination campaigns such as mass drug administration (MDA). Uncertainty about the therapeutic dose range (TDR) required fo...

    Authors: Daniel Joseph Hayes, Clifford George Banda, Alexandra Chipasula-Teleka and Dianne Janette Terlouw

    Citation: BMC Infectious Diseases 2017 17:254

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  5. Content type: Research article

    Schistosomiasis, one of the neglected tropical diseases, is endemic in more than 70 countries. However, the clinical diagnosis of patients with a low degree of infection is an unsolved...

    Authors: Kongzhen Gu, Yuesheng Li, Patrick Driguez, Qingren Zeng, Xinlin Yu, Hui Sun, Liting Cai, Yongkang He, Wenyang Wang and Donald P. McManus

    Citation: BMC Infectious Diseases 2017 17:244

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  6. Content type: Research article

    Leishmaniasis is a spectrum of diseases with great relevance to public health. Conventional diagnostic methods are time consuming, needing trained personnel. A robust, rapid and cost effective diagnostic test ...

    Authors: Sandeep Verma, Ruchi Singh, Vanila Sharma, Ram Avtar Bumb, Narendra Singh Negi, V Ramesh and Poonam Salotra

    Citation: BMC Infectious Diseases 2017 17:223

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  7. Content type: Research article

    Chagas disease is caused by the protozoan Trypanosoma cruzi and is characterized by heart failure and sudden death. Identifying which factors are involved in evolution and treatment response is actually challengi...

    Authors: Héctor Rodríguez-Angulo, Juan Marques, Ivan Mendoza, Marco Villegas, Alfredo Mijares, Núria Gironès and Manuel Fresno

    Citation: BMC Infectious Diseases 2017 17:221

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  8. Content type: Research article

    Very little is known about the link of T. gondii infection and depression. Through an age-, gender-, and month of pregnancy-matched case-control study, we determined the association of T. gondii infection and dep...

    Authors: Cosme Alvarado-Esquivel, Ana Liliana Martínez-Martínez, Luis Francisco Sánchez-Anguiano, Jesús Hernández-Tinoco, Juan Manuel Castillo-Orona, Carlos Salas-Martínez, Antonio Sifuentes-Álvarez, Ada Agustina Sandoval-Carrillo, José M. Salas-Pacheco, Oliver Liesenfeld and Elizabeth Irasema Antuna-Salcido

    Citation: BMC Infectious Diseases 2017 17:190

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  9. Content type: Research article

    Clinical manifestations of cutaneous leishmaniasis (CL) caused by Leishmania (Viannia) range from asymptomatic infection to self-limited, or chronic (non-healing) cutaneous lesions. Given the critical role of the...

    Authors: Angélica Mera-Ramírez, Andrés Castillo, Yenifer Orobio, María Adelaida Gómez and Carolina Gallego-Marin

    Citation: BMC Infectious Diseases 2017 17:177

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  10. Content type: Research article

    Visceral leishmaniasis (VL) is an important and potentially fatal neglected tropical disease. The aim of this study was to investigate hyponatremia and risk factors for death among VL patients.

    Authors: Elizabeth De Francesco Daher, Douglas de Sousa Soares, Sérgio Luiz Arruda Parente Filho, Gdayllon Cavalcante Meneses, Tainá Veras de Sandes Freitas, Tacyano Tavares Leite and Geraldo Bezerra da Silva Junior

    Citation: BMC Infectious Diseases 2017 17:168

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  11. Content type: Research article

    Current diagnostic methods for Schistosoma japonicum infection are insensitive for low-density infections. Therefore, a new diagnostic assay based on recombinase polymerase amplification (RPA) technology was esta...

    Authors: Weiwei Xing, Xinling Yu, Jingtao Feng, Kui Sun, Wenliang Fu, Yuanyuan Wang, Minji Zou, Wenrong Xia, Zhihong Luo, Hongbin He, Yuesheng Li and Donggang Xu

    Citation: BMC Infectious Diseases 2017 17:164

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  12. Content type: Research article

    Early rising asexual parasitaemia (ERAP), initially defined as ‘an increase in the parasite count over the baseline pre-treatment level during the first 24 h of treatment’ of falciparum malaria with artemisini...

    Authors: Akintunde Sowunmi, Kazeem Akano, Adejumoke I. Ayede, Elsie O. Adewoye, Godwin Ntadom, Bayo Fatunmbi, Grace O. Gbotosho, Onikepe A. Folarin and Christian T. Happi

    Citation: BMC Infectious Diseases 2017 17:110

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  13. Content type: Case report

    Neurocysticercosis is endemic in most countries of Central and South America but has rarely been described in the French West Indies. We aimed to better understand the clinical and radiological presentation of...

    Authors: R. Blaizot, B. Melot, K. Schepers, M. Nicolas, S. Gaumond, P. Poullain, L. Belaye, A. Lannuzel and B. Hoen

    Citation: BMC Infectious Diseases 2017 17:106

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  14. Content type: Case report

    Mucocutaneous leishmaniasis (MCL), a protozoan infectious disease, is very rare in Iran despite the endemicity of both cutaneous and visceral forms. It is transmitted by the Phlebotomus sand fly. The lip is consi...

    Authors: Iraj Mohammadpour, Mohammad Hossein Motazedian, Farhad Handjani and Gholam Reza Hatam

    Citation: BMC Infectious Diseases 2017 17:96

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  15. Content type: Case report

    Visceral leishmaniasis (VL) is a protozoan disease, which is responsible for 200.000–400.000 yearly infections worldwide. If left untreated, the fatality rate can be as high as 100% within 2 years. 90% of case...

    Authors: Anna Eichenberger, Annina E. Buechi, Andreas Neumayr, Chistroph Hatz, Andri Rauch, Marc Huguenot, Eva Diamantis-Karamitopoulou and Cornelia Staehelin

    Citation: BMC Infectious Diseases 2017 17:81

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  16. Content type: Research article

    Toxoplasma gondii (T. gondii) is an obligate intracellular protozoan parasite with a broad host range including most warm-blooded animals, including humans. T. gondii surface antigen 1...

    Authors: Yali Han, Aihua Zhou, Gang Lu, Guanghui Zhao, Lin Wang, Jingjing Guo, Pengxia Song, Jian Zhou, Huaiyu Zhou, Hua Cong and Shenyi He

    Citation: BMC Infectious Diseases 2017 17:59

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  17. Content type: Debate

    Bidirectional signalling between the brain and the gastrointestinal tract is regulated at neural, hormonal, and immunological levels. Recent studies have shown that helminth infections can alter the normal gut...

    Authors: Vanina Guernier, Bradley Brennan, Laith Yakob, Gabriel Milinovich, Archie C. A. Clements and Ricardo J. Soares Magalhaes

    Citation: BMC Infectious Diseases 2017 17:58

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  18. Content type: Research article

    Sri Lanka achieved the WHO certificate as a malaria free country in September 2016, thus monitoring of malaria transmission using sensitive and effective tools is an important need. Use of age-specific antibod...

    Authors: Rajika Lasanthi Dewasurendra, Janaka Nandana Dias, Nuno Sepulveda, Geethika Sharmini Abayaweera Gunawardena, Naduviladath Chandrasekharan, Chris Drakeley and Nadira Dharshani Karunaweera

    Citation: BMC Infectious Diseases 2017 17:49

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  19. Content type: Research article

    Toxoplasmosis is a neglected zoonotic disease which is prevalent among pregnant women especially in Africa. This study aimed to determine the seroprevalence and determinants of the disease among pregnant women...

    Authors: Christiana Frimpong, Mpundu Makasa, Lungowe Sitali and Charles Michelo

    Citation: BMC Infectious Diseases 2017 17:10

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